GR3019527T3 - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number: GR3019527T3
Authority: GR; Greece
Prior art keywords: lower alkyl; ring; hydrogen; heterocyclic compounds; specified
Prior art date: 1989-10-14

Application number

GR960400917T

Other languages

English (en)

Inventor

Terence James Ward

Janet Christine White

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-14

Filing date

1996-04-02

Publication date

1996-07-31

1989-10-14 Priority claimed from GB898923209A external-priority patent/GB8923209D0/en

1990-05-04 Priority claimed from GB909010085A external-priority patent/GB9010085D0/en

1996-04-02 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1996-07-31 Publication of GR3019527T3 publication Critical patent/GR3019527T3/el

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Earth Drilling (AREA)
Stereophonic System (AREA)
Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Thiazole And Isothizaole Compounds (AREA)
Luminescent Compositions (AREA)

GR960400917T 1989-10-14 1996-04-02 Heterocyclic compounds GR3019527T3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB898923209A GB8923209D0 (en)	1989-10-14	1989-10-14	Heterocyclic compounds
GB909010085A GB9010085D0 (en)	1990-05-04	1990-05-04	Heterocyclic compounds
PCT/GB1990/001561 WO1991005783A1 (en)	1989-10-14	1990-10-10	Heterocyclic compounds

Publications (1)

Publication Number	Publication Date
GR3019527T3 true GR3019527T3 (en)	1996-07-31

Family

ID=26296055

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR960400917T GR3019527T3 (en)	1989-10-14	1996-04-02	Heterocyclic compounds

Country Status (16)

Country	Link
US (2)	US5096901A (el)
EP (1)	EP0494978B1 (el)
JP (1)	JPH05501255A (el)
KR (1)	KR0154316B1 (el)
AT (1)	ATE134631T1 (el)
AU (1)	AU636179B2 (el)
CA (1)	CA2066640C (el)
DE (1)	DE69025621T2 (el)
DK (1)	DK0494978T3 (el)
ES (1)	ES2083464T3 (el)
FI (1)	FI921560L (el)
GB (1)	GB2236751B (el)
GR (1)	GR3019527T3 (el)
IE (1)	IE64455B1 (el)
PT (1)	PT95583B (el)
WO (1)	WO1991005783A1 (el)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
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GB2236751B (en) *	1989-10-14	1993-04-28	Wyeth John & Brother Ltd	Heterocyclic compounds
JP3122671B2 (ja) *	1990-05-23	2001-01-09	協和醗酵工業株式会社	複素環式化合物
JPH05310732A (ja) *	1992-03-12	1993-11-22	Mitsubishi Kasei Corp	シンノリン−３−カルボン酸誘導体
JP2699794B2 (ja) *	1992-03-12	1998-01-19	三菱化学株式会社	チエノ〔３，２−ｂ〕ピリジン誘導体
FR2694005B1 (fr) *	1992-07-21	1994-08-26	Adir	Nouvelles aminoalkylchromones, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
GB9314174D0 (en) *	1993-07-08	1993-08-18	American Home Prod	5-ht3-antagonists
US5663182A (en) *	1993-08-19	1997-09-02	Bymaster; Franklin Porter	Antipsychotic method
DE4424369A1 (de) *	1994-07-11	1996-01-18	Bayer Ag	Pyrido[3,2,1.i,j][3,1]benzoxazinderivate
US5749111A (en)	1996-02-14	1998-05-12	Teksource, Lc	Gelatinous cushions with buckling columns
US5792774A (en) *	1996-02-21	1998-08-11	Chiroscience Limited	Quinolones and their therapeutic use
PE20011349A1 (es)	2000-06-16	2002-01-19	Upjohn Co	1-aril-4-oxo-1,4-dihidro-3-quinolincarboxamidas como agentes antivirales
US6525049B2 (en)	2000-07-05	2003-02-25	Pharmacia & Upjohn Company	Pyrroloquinolones as antiviral agents
AR036040A1 (es)	2001-06-12	2004-08-04	Upjohn Co	Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) *	2001-06-12	2004-08-04	Upjohn Co	Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
WO2003022856A1 (en) *	2001-09-12	2003-03-20	Pharmacia & Upjohn Company	Substituted 7-aza[2.2.1] bicycloheptanes for the treatment of diseases
JP2005510523A (ja)	2001-11-09	2005-04-21	ファルマシアアンドアップジョンカンパニーリミティドライアビリティーカンパニー	アザ二環式フェニル縮合複素環式化合物、及びα７ＮＡＣＨＲリガンドとしての当該化合物の使用
CA2503786A1 (en) *	2002-11-01	2004-05-13	Pharmacia & Upjohn Company Llc	Compounds having both alpha7 nicotinic agonist activity and 5ht, antagonist activity for treatment of cns diseases
PL2489659T3 (pl)	2004-06-24	2018-06-29	Vertex Pharma	Modulatory transporterów posiadających kasetę wiążącą atp
DE602005016446D1 (de) *	2004-11-05	2009-10-15	Theravance Inc	5-HT4-Rezeptoragonistenverbindungen
ES2327142T3 (es) *	2004-11-05	2009-10-26	Theravance, Inc.	Compuestos de quinolinona-carboxamida.
PT1993360T (pt)	2005-12-28	2017-05-25	Vertex Pharma	Formas sólidas de n-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-di-hidro-4-oxoquinolina-3-carboxamida
JP2010208947A (ja) *	2007-06-29	2010-09-24	Dainippon Sumitomo Pharma Co Ltd	キノロン誘導体
US8075981B2 (en)	2007-08-23	2011-12-13	Edizone, Llc	Alternating pattern gel cushioning elements and related methods
US8697722B2 (en) *	2007-11-02	2014-04-15	Sri International	Nicotinic acetylcholine receptor modulators
US20100074949A1 (en)	2008-08-13	2010-03-25	William Rowe	Pharmaceutical composition and administration thereof
US12458635B2 (en)	2008-08-13	2025-11-04	Vertex Pharmaceuticals Incorporated	Pharmaceutical composition and administrations thereof
ES2683633T3 (es)	2009-03-20	2018-09-27	Vertex Pharmaceuticals Incorporated	Moduladores de regulador de conductancia transmembrana de la fibrosis quística
EP3330255B1 (en)	2009-03-20	2020-12-09	Vertex Pharmaceuticals Incorporated	Process for making modulators of cystic fibrosis transmembrane conductance regulator
EP2523562B1 (en) *	2010-01-11	2019-01-02	Astraea Therapeutics, LLC	Nicotinic acetylcholine receptor modulators
IL311180A (en)	2012-02-27	2024-04-01	Vertex Pharma	Pharmaceutical preparations containing a solid dispersion of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and uses thereof
JP6211509B2 (ja)	2012-03-02	2017-10-11	武田薬品工業株式会社	複素環化合物およびその用途
US9777005B2 (en)	2012-11-19	2017-10-03	Takeda Pharmaceutical Company Limited	Bicyclic heterocyclic compound containing a substituted pyrrole ring
RU2020122711A (ru)	2017-12-13	2022-01-17	ПРАКСИС БАЙОТЕК ЭлЭлСи	Ингибиторы пути интегрированной реакции на стресс
SG11202011014VA (en)	2018-06-05	2020-12-30	Praxis Biotech LLC	Inhibitors of integrated stress response pathway
CA3142748A1 (en) *	2019-06-12	2020-12-17	Praxis Biotech LLC	Modulators of integrated stress response pathway

Family Cites Families (11)

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FI74707C (fi)	1982-06-29	1988-03-10	Sandoz Ag	Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
WO1984000381A1 (en) *	1982-07-09	1984-02-02	Thompson Boyce Plant Res	Genetic engineering in procaryotic organism
WO1984003281A1 (en) *	1983-02-19	1984-08-30	Beecham Group Plc	Azabicycloalkyl benzamide and anilide derivatives
DE3429830A1 (de) *	1983-08-26	1985-03-07	Sandoz-Patent-GmbH, 7850 Lörrach	Automatische carbonsaeure- und sulfonsaeureester oder -amide
IL74165A (en)	1984-01-25	1988-11-15	Glaxo Group Ltd	1,2,3,9-tetrahydro-3-(1h-imidazole-1-yl methyl)-4h-carbazol-4-one compounds,their preparation and pharmaceutical compositions containing them
EP0200444B1 (en)	1985-04-27	1992-11-11	Beecham Group Plc	Azabicyclononyl-indazole-carboxamide having 5-ht antagonist activity
DE3827253A1 (de) *	1987-08-20	1989-03-02	Sandoz Ag	Ester und amide von cyclischen carbonsaeuren und cyclischen alkoholen und aminen sowie verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
IE63474B1 (en)	1987-12-24	1995-04-19	Wyeth John & Brother Ltd	Heterocyclic compounds
IT1228293B (it) *	1989-02-06	1991-06-07	Angeli Inst Spa	Benzoderivati di composti eterociclici contenenti azoto.
US5225419A (en) *	1989-10-14	1993-07-06	John Wyeth & Brother, Limited	Certain 1,8-ethano or propano-1,4-dihydro-4-oxo-quinoline-3-carboxamides and derivatives thereof
GB2236751B (en) *	1989-10-14	1993-04-28	Wyeth John & Brother Ltd	Heterocyclic compounds

1990
- 1990-10-05 GB GB9021697A patent/GB2236751B/en not_active Revoked
- 1990-10-09 IE IE361790A patent/IE64455B1/en not_active IP Right Cessation
- 1990-10-10 US US07/595,333 patent/US5096901A/en not_active Expired - Lifetime
- 1990-10-10 EP EP90915801A patent/EP0494978B1/en not_active Expired - Lifetime
- 1990-10-10 AT AT90915801T patent/ATE134631T1/de not_active IP Right Cessation
- 1990-10-10 JP JP2514808A patent/JPH05501255A/ja active Pending
- 1990-10-10 CA CA002066640A patent/CA2066640C/en not_active Expired - Fee Related
- 1990-10-10 DK DK90915801.6T patent/DK0494978T3/da active
- 1990-10-10 AU AU66210/90A patent/AU636179B2/en not_active Ceased
- 1990-10-10 DE DE69025621T patent/DE69025621T2/de not_active Expired - Fee Related
- 1990-10-10 WO PCT/GB1990/001561 patent/WO1991005783A1/en not_active Ceased
- 1990-10-10 KR KR1019920700862A patent/KR0154316B1/ko not_active Expired - Fee Related
- 1990-10-10 FI FI921560A patent/FI921560L/fi unknown
- 1990-10-10 ES ES90915801T patent/ES2083464T3/es not_active Expired - Lifetime
- 1990-10-12 PT PT95583A patent/PT95583B/pt not_active IP Right Cessation
1993
- 1993-02-18 US US08/019,005 patent/US5362734A/en not_active Expired - Lifetime
1996
- 1996-04-02 GR GR960400917T patent/GR3019527T3/el unknown

Also Published As

Publication number	Publication date
EP0494978A1 (en)	1992-07-22
ATE134631T1 (de)	1996-03-15
GB9021697D0 (en)	1990-11-21
KR0154316B1 (ko)	1998-11-16
CA2066640A1 (en)	1991-04-15
AU636179B2 (en)	1993-04-22
JPH05501255A (ja)	1993-03-11
IE64455B1 (en)	1995-08-09
GB2236751A (en)	1991-04-17
WO1991005783A1 (en)	1991-05-02
DE69025621D1 (de)	1996-04-04
EP0494978B1 (en)	1996-02-28
US5362734A (en)	1994-11-08
DE69025621T2 (de)	1996-07-04
IE903617A1 (en)	1991-04-24
CA2066640C (en)	2000-08-01
AU6621090A (en)	1991-05-16
FI921560A0 (fi)	1992-04-08
PT95583B (pt)	1997-08-29
KR927003585A (ko)	1992-12-18
DK0494978T3 (da)	1996-03-18
ES2083464T3 (es)	1996-04-16
FI921560A7 (fi)	1992-04-08
US5096901A (en)	1992-03-17
FI921560L (fi)	1992-04-08
PT95583A (pt)	1991-09-13
GB2236751B (en)	1993-04-28

Publication	Publication Date	Title
GB2236751B (en)	1993-04-28	Heterocyclic compounds
ATE86110T1 (de)	1993-03-15	Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten.
SE7714184L (sv)	1978-06-15	Piperazinderivat
DK0618920T3 (da)	1996-12-30	Hidtil ukendte phosphonravsyrederivater, fremgangsmåde til fremstilling heraf samt lægemidler indeholdende disse forbindelser
DK598688A (da)	1989-04-29	Spiro-oxathiolan/quinuclidin
GR3004250T3 (el)	1993-03-31
ATE2670T1 (de)	1986-03-15	4-phenoxypiperidine, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel.
ATE27806T1 (de)	1987-07-15	Norbornan- und norbornencarbonsaeureamide und verfahren zu deren herstellung.
NO954763L (no)	1996-01-25	Piperidinderivater, deres fremstilling og anvendelse
ATE48994T1 (de)	1990-01-15	Benzimidazol-derivat, verfahren zu seiner herstellung und pharmazeutische zusammensetzung.
ES468127A1 (es)	1979-09-16	Un procedimiento para la preparacion de nuevos derivados de pirido (2,1-b) quinazolina
HUT58086A (en)	1992-01-28	Process for producing new thienloxyalkyl derivatives andpharmaceutical compositions comprising same
HRP940825A2 (en)	1996-04-30	Process for the preparation of basically susbtituted 5-halothienoisothiazol-3(2h)-one-1,1-dioxides
DK0432841T3 (da)	1996-06-24	Spiro-indolin-oxazin-forbindelser med fotokromatiske og fotosensibiliserende egenskaber samt fremgangsmåde til deres fremstilling
GEP19970835B (en)	1997-02-10	Process for obtaining 3-(methyltio, methylsulphinyl or methylsulphonyl)-4-quinolone
DE3068245D1 (en)	1984-07-19	Substituted 2-phenylamino-2-imidazolines, acid addition salts thereof, medicaments containing them and process for preparing them
ES2031921T3 (es)	1993-01-01	Derivados 5-aminoetilados de la oxazolidinona-2, su procedimiento de fabricacion y su aplicacion terapeutica.
JPS5515415A (en)	1980-02-02	Heterocyclic compound and its preparation
ES478143A1 (es)	1980-07-01	Un procedimiento para la fabricacion de compuestos heteroci-clicos nitrogenados.
ZA923502B (en)	1993-10-04	1-amidoocthydropyrido[2,1-c][1,4]oxazine compounds, processes for preparing these and pharmaceutical compositions containing them
SE7901707L (sv)	1979-08-28	2-betoxibensamider
ES8307812A1 (es)	1983-08-01	Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo.
ES247867A1 (es)	1959-09-16	Un procedimiento para la preparacion de compuestos terapeuticos
MY104164A (en)	1994-02-28	Heterocyclic compounds.