GR3000026T3 - Amino alcohols, process for their preparation and their applications, in particular for therepeutical use - Google Patents
Amino alcohols, process for their preparation and their applications, in particular for therepeutical useInfo
- Publication number
- GR3000026T3 GR3000026T3 GR89400002T GR890400002T GR3000026T3 GR 3000026 T3 GR3000026 T3 GR 3000026T3 GR 89400002 T GR89400002 T GR 89400002T GR 890400002 T GR890400002 T GR 890400002T GR 3000026 T3 GR3000026 T3 GR 3000026T3
- Authority
- GR
- Greece
- Prior art keywords
- alkyl
- compound
- nitrogen
- cycle
- carbon atoms
- Prior art date
Links
- 150000001414 amino alcohols Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 14
- 150000001875 compounds Chemical class 0.000 abstract 14
- 229910052757 nitrogen Inorganic materials 0.000 abstract 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 6
- 125000003342 alkenyl group Chemical group 0.000 abstract 5
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 5
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 5
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 4
- 239000005864 Sulphur Substances 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 4
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 4
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 4
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 4
- 229910052760 oxygen Inorganic materials 0.000 abstract 4
- 239000001301 oxygen Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 3
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 3
- 229910000091 aluminium hydride Inorganic materials 0.000 abstract 3
- 229910010277 boron hydride Inorganic materials 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 3
- 229920006395 saturated elastomer Polymers 0.000 abstract 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 2
- 235000019253 formic acid Nutrition 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Heat Treatment Of Sheet Steel (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8601295A FR2593499B1 (fr) | 1986-01-30 | 1986-01-30 | Aminoalcools, leur procede de preparation et leurs applications, notamment en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3000026T3 true GR3000026T3 (en) | 1990-01-19 |
Family
ID=9331637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR89400002T GR3000026T3 (en) | 1986-01-30 | 1989-07-26 | Amino alcohols, process for their preparation and their applications, in particular for therepeutical use |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4994617A (el) |
| EP (1) | EP0237366B1 (el) |
| JP (1) | JPH089580B2 (el) |
| KR (1) | KR950006891B1 (el) |
| AT (1) | ATE42540T1 (el) |
| AU (1) | AU590664B2 (el) |
| BR (1) | BR1100977A (el) |
| CA (1) | CA1294961C (el) |
| DE (1) | DE3760117D1 (el) |
| DK (1) | DK169538B1 (el) |
| ES (1) | ES2008109B3 (el) |
| FI (1) | FI87068C (el) |
| FR (1) | FR2593499B1 (el) |
| GR (1) | GR3000026T3 (el) |
| IE (1) | IE59448B1 (el) |
| NZ (1) | NZ218988A (el) |
| PT (1) | PT84223B (el) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939133A (en) * | 1985-10-01 | 1990-07-03 | Warner-Lambert Company | N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade |
| US5482947A (en) * | 1990-11-19 | 1996-01-09 | Talley; John J. | Retroviral protease inhibitors |
| US5472970A (en) * | 1992-05-05 | 1995-12-05 | Institut De Recherche Jouveinal S.A. | Allylaminoesters and their application in therapeutics |
| FR2690917B1 (fr) * | 1992-05-05 | 1994-06-17 | Jouveinal Inst Rech | Aminoesters, leur procede de preparation et leur application en therapeutique. |
| FR2690916B1 (fr) * | 1992-05-05 | 1994-06-17 | Jouveinal Inst Rech | Nouveaux enantiomeres derives du (s)-amino-2-(dichloro-3,4-benzyl)-2-propanol-1. |
| US5367094A (en) * | 1993-06-04 | 1994-11-22 | Yukong, Ltd. | Convenient process for the preparation of chiral or racemic phenylalaninols and their N-blocked derivatives |
| FR2761686B1 (fr) * | 1997-04-07 | 1999-05-14 | Sipsy Sa | Nouveau procede de preparation du (+/-)3-(3,4- dichlorophenyl)-2-dimethylamino-2-methyl-propan-1-ol ou cericlamine (inn) |
| US7216702B2 (en) * | 2003-02-28 | 2007-05-15 | Yates Petroleum Corporation | Methods of evaluating undersaturated coalbed methane reservoirs |
| EP2343073A3 (en) | 2003-12-11 | 2011-10-12 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| US7467260B2 (en) * | 2004-10-08 | 2008-12-16 | International Business Machines Corporation | Method and apparatus to purge remote node cache lines to support hot node replace in a computing system |
| CZ2009385A3 (cs) * | 2009-06-16 | 2010-07-28 | Zentiva, K. S. | Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3132179A (en) * | 1959-08-27 | 1964-05-05 | Sterling Drug Inc | Ethers of alpha-hydroxymethyl-beta-monocarbocyclic aryl ethyl amines and their preparation |
| US3193581A (en) * | 1961-03-01 | 1965-07-06 | Yamanouchi Pharma Co Ltd | Process of preparing 1-phenyl-2-aminopropane |
| US3573304A (en) * | 1968-12-03 | 1971-03-30 | Delalande Sa | 1-dimethylamino - 3 - methyl-2(pyridyl or pyridazinyl) pentane and the corresponding non-toxic acid addition salts thereof |
| US3706764A (en) * | 1969-04-16 | 1972-12-19 | Yoshitomi Pharmaceutical | Phenethylaminomethyl-chromanones and- thiochromanones |
| US3896166A (en) * | 1970-05-06 | 1975-07-22 | Hoffmann La Roche | Formyl-substituted tyrosine |
| NL7112938A (el) * | 1970-09-30 | 1972-04-05 | ||
| ES399820A1 (es) * | 1971-02-17 | 1975-07-01 | Sandoz Ag | Procedimiento para la obtencion de derivados de amino pro- panol. |
| GB1346401A (en) * | 1971-05-12 | 1974-02-13 | Lepetit Spa | Cardioactive arylaminobutanols |
| US4058642A (en) * | 1973-10-11 | 1977-11-15 | Boehringer Ingelheim Gmbh | 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof |
| GB1434826A (en) * | 1973-11-14 | 1976-05-05 | Gallardo Antonio Sa | Esters and carbamates of aminoalkanols |
| US4536601A (en) * | 1982-09-28 | 1985-08-20 | Dainippon Pharmaceutical Co., Ltd. | Optically active N-substituted phenylalaninols and use thereof |
-
1986
- 1986-01-30 FR FR8601295A patent/FR2593499B1/fr not_active Expired
-
1987
- 1987-01-09 IE IE6287A patent/IE59448B1/en not_active IP Right Cessation
- 1987-01-19 DE DE8787400116T patent/DE3760117D1/de not_active Expired
- 1987-01-19 ES ES87400116T patent/ES2008109B3/es not_active Expired
- 1987-01-19 EP EP87400116A patent/EP0237366B1/fr not_active Expired
- 1987-01-19 AT AT87400116T patent/ATE42540T1/de not_active IP Right Cessation
- 1987-01-20 NZ NZ218988A patent/NZ218988A/xx unknown
- 1987-01-23 AU AU67959/87A patent/AU590664B2/en not_active Ceased
- 1987-01-26 DK DK040687A patent/DK169538B1/da not_active IP Right Cessation
- 1987-01-28 CA CA000528425A patent/CA1294961C/en not_active Expired - Lifetime
- 1987-01-29 PT PT84223A patent/PT84223B/pt not_active IP Right Cessation
- 1987-01-30 KR KR1019870000797A patent/KR950006891B1/ko not_active Expired - Fee Related
- 1987-01-30 JP JP62018769A patent/JPH089580B2/ja not_active Expired - Fee Related
- 1987-01-30 FI FI870418A patent/FI87068C/fi not_active IP Right Cessation
-
1989
- 1989-07-26 GR GR89400002T patent/GR3000026T3/el unknown
- 1989-12-26 US US07/456,743 patent/US4994617A/en not_active Expired - Lifetime
-
1997
- 1997-05-14 BR BR1100977-2A patent/BR1100977A/pt active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DK169538B1 (da) | 1994-11-28 |
| FI87068B (fi) | 1992-08-14 |
| US4994617A (en) | 1991-02-19 |
| BR1100977A (pt) | 1999-10-13 |
| IE870062L (en) | 1987-07-30 |
| FI870418A0 (fi) | 1987-01-30 |
| EP0237366A1 (fr) | 1987-09-16 |
| CA1294961C (en) | 1992-01-28 |
| FI870418L (fi) | 1987-07-31 |
| JPH089580B2 (ja) | 1996-01-31 |
| FI87068C (fi) | 1992-11-25 |
| IE59448B1 (en) | 1994-02-23 |
| FR2593499B1 (fr) | 1988-08-12 |
| DK40687D0 (da) | 1987-01-26 |
| EP0237366B1 (fr) | 1989-04-26 |
| AU590664B2 (en) | 1989-11-09 |
| KR950006891B1 (ko) | 1995-06-26 |
| ATE42540T1 (de) | 1989-05-15 |
| KR870007101A (ko) | 1987-08-14 |
| PT84223B (pt) | 1989-05-31 |
| PT84223A (fr) | 1987-02-01 |
| DK40687A (da) | 1987-07-31 |
| AU6795987A (en) | 1987-08-06 |
| JPS62190150A (ja) | 1987-08-20 |
| NZ218988A (en) | 1990-02-26 |
| FR2593499A1 (fr) | 1987-07-31 |
| DE3760117D1 (en) | 1989-06-01 |
| ES2008109B3 (es) | 1989-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3760117D1 (en) | Amino alcohols, process for their preparation and their applications, in particular for therepeutical use | |
| DE3276114D1 (en) | Novel (2-haloergolinyl)-n'-n'-diethylurea derivatives, process for the preparation thereof, and use thereof as medicinal agents | |
| EP0237084A3 (en) | 1,3-dioxolen-2-one derivative, 4-bromomethyl-5-methyl-1,3-dioxolen-2-one, and a process for the production thereof | |
| HUT48583A (en) | Process for production of derivatives of substituated indolinon | |
| Hassner et al. | Cycloaddition of vinyl aziridines with unsaturated substrates. A novel rearrangement of an unsaturated nitro compound. | |
| IN167606B (el) | ||
| FI953673A0 (fi) | Menetelmä tioamidien valmistamiseksi | |
| EP0217736A3 (en) | 1,2-disubstituted ergoline derivatives | |
| YU40388A (en) | Process for making imidazole derivatives | |
| DE3276905D1 (en) | Process for the preparation of 3,4-dihydro-alpha-pyrones | |
| ES514256A0 (es) | "procedimiento de preparar compuestos 6,7-dietoxi-1-(4-etoxi-3-hidroxibencil)-384-dihidroisoquinolinicos". | |
| DE69007203D1 (de) | Imidazolderivate, Verfahren zu deren Herstellung und diese enthaltende Antiulkusmittel. | |
| IL58311A0 (en) | Isomerisation of 3-azabicyvlo (3.1.0)hexane derivatives | |
| DE3760058D1 (en) | 3,4-dihydro-2,5,7,8-tetramethyl-2h-1-benzopyran derivatives and processes for their preparation | |
| HUT50760A (en) | New process for production of substituated guanil-tio-carbamides | |
| DE3060292D1 (en) | Imidazo and pyrimido-pyrido indoles, their preparation and medicines containing them | |
| RO99496B1 (ro) | Procedeu pentru prepararea unor derivati de pirazolsulfonamida | |
| PL237696A1 (en) | Process for preparing derivatives of 5/6/-thiocyanatebenzimidazole | |
| DE3760334D1 (en) | Process for the preparation of a 6-halogen-3-methyl-1-trialkylsilyloxy-1,3,5-hexatriene | |
| KR900012924A (ko) | 피리돈 카르복시산 유도체의 제조방법 | |
| RO85554B1 (ro) | Procedeu pentru prepararea unor derivati de aminoacizi | |
| RO95817B1 (ro) | Procedeu pentru prepararea unor derivati de benzamida |