GB8827389D0 - Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide - Google Patents
Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamideInfo
- Publication number
- GB8827389D0 GB8827389D0 GB888827389A GB8827389A GB8827389D0 GB 8827389 D0 GB8827389 D0 GB 8827389D0 GB 888827389 A GB888827389 A GB 888827389A GB 8827389 A GB8827389 A GB 8827389A GB 8827389 D0 GB8827389 D0 GB 8827389D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrrolidineacetamide
- oxo
- alpha
- ethyl
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HPHUVLMMVZITSG-LURJTMIESA-N levetiracetam Chemical compound CC[C@@H](C(N)=O)N1CCCC1=O HPHUVLMMVZITSG-LURJTMIESA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888827389A GB8827389D0 (en) | 1988-11-23 | 1988-11-23 | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| BG090398A BG51041A3 (bg) | 1988-11-23 | 1989-11-20 | Метод за получаване на (s)-алфа-етил-2-оксо-1- пиролидинацетамид |
| GR890100769A GR1000719B (el) | 1988-11-23 | 1989-11-20 | Μεθοδος παρασκευης της (s)-α-εθυλ-2-οξο-1-πυρρολιδινοακεταμιδης. |
| PT92365A PT92365B (pt) | 1988-11-23 | 1989-11-21 | Processo para a preparacao de (s)-alfa-etil-2-oxo-1-pirrolidinoacetamida |
| GB8926244A GB2225322B (en) | 1988-11-23 | 1989-11-21 | A process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| AT2666/89A AT392781B (de) | 1988-11-23 | 1989-11-22 | Verfahren zur herstellung von (s)-alpha-ethyl-2- oxo-1-pyrrolidinacetamid |
| CN89108764A CN1020604C (zh) | 1988-11-23 | 1989-11-22 | 制备(S)-α-乙基-2-氧代-1-吡咯烷基乙酰胺的方法 |
| SU4742434A RU1797607C (ru) | 1988-11-23 | 1989-11-22 | Способ получени /S/- @ -этил-2-оксо-1-пирролидинацетамида |
| NO894649A NO173823C (no) | 1988-11-23 | 1989-11-22 | Fremgangsmaate for fremstilling av (s)- -ethyl-2-oxo-1-pyrrolidinacetamid og mellomprodukt for anvendelse ved fremgangsmaaten |
| ES8903978A ES2023532A6 (es) | 1988-11-23 | 1989-11-22 | Procedimiento de preparacion de (s)-*-etil-2-oxo-1-pirrolidinoacetamida> |
| FI895562A FI91961C (fi) | 1988-11-23 | 1989-11-22 | Menetelmä (S)- -etyyli-2-okso-1-pyrrolidiiniasetamidin valmistamiseksi |
| HU896132A HU204508B (en) | 1988-11-23 | 1989-11-22 | Process for producing (s)-alpha-ethyl-2-oxo-1-pyrrolidin-acetamide |
| PL89282413A PL161781B1 (en) | 1988-11-23 | 1989-11-22 | Method of obtaining (s)-alpha-ethyl-2-keto-1-pyrolidyne acetamide |
| PH39568A PH26332A (en) | 1988-11-23 | 1989-11-23 | A process for the preparation of (S)-ethyl-2-oxo-1-pyrrolidineacetamide |
| KR1019890017038A KR0157610B1 (ko) | 1988-11-23 | 1989-11-23 | (S)-α-에틸-2-옥소-1-피롤리딘아세트 아미드의 제법 |
| SG893/92A SG89392G (en) | 1988-11-23 | 1992-09-05 | A process for the preparation of(s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| HK1024/92A HK102492A (en) | 1988-11-23 | 1992-12-17 | A process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| CY1672A CY1672A (en) | 1988-11-23 | 1993-05-14 | A process for the preparation of(s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888827389A GB8827389D0 (en) | 1988-11-23 | 1988-11-23 | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB8827389D0 true GB8827389D0 (en) | 1988-12-29 |
Family
ID=10647345
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB888827389A Pending GB8827389D0 (en) | 1988-11-23 | 1988-11-23 | Process for preparation of(s)alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| GB8926244A Expired - Lifetime GB2225322B (en) | 1988-11-23 | 1989-11-21 | A process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8926244A Expired - Lifetime GB2225322B (en) | 1988-11-23 | 1989-11-21 | A process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
Country Status (17)
| Country | Link |
|---|---|
| KR (1) | KR0157610B1 (pt) |
| CN (1) | CN1020604C (pt) |
| AT (1) | AT392781B (pt) |
| BG (1) | BG51041A3 (pt) |
| CY (1) | CY1672A (pt) |
| ES (1) | ES2023532A6 (pt) |
| FI (1) | FI91961C (pt) |
| GB (2) | GB8827389D0 (pt) |
| GR (1) | GR1000719B (pt) |
| HK (1) | HK102492A (pt) |
| HU (1) | HU204508B (pt) |
| NO (1) | NO173823C (pt) |
| PH (1) | PH26332A (pt) |
| PL (1) | PL161781B1 (pt) |
| PT (1) | PT92365B (pt) |
| RU (1) | RU1797607C (pt) |
| SG (1) | SG89392G (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9319732D0 (en) | 1993-09-24 | 1993-11-10 | Ucb Sa | Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety |
| US6107492A (en) * | 1998-05-08 | 2000-08-22 | Ucb, S.A. | Process for the preparation of levetiracetam |
| WO2001039779A1 (en) | 1999-12-01 | 2001-06-07 | Ucb, S.A. | A pyrrolidineacetamide derivative alone or in combination for treatment of cns disorders |
| GB0004297D0 (en) | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
| RU2216322C1 (ru) * | 2002-02-28 | 2003-11-20 | Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" | Средство, обладающее антиишемической, гипотензивной, противоаритмической и ноотропной активностью |
| WO2004069796A2 (en) * | 2003-02-03 | 2004-08-19 | Teva Pharmaceutical Industries Ltd. | Process for producing levetiracetam |
| ES2214147B1 (es) * | 2003-02-28 | 2005-10-01 | Farma-Lepori S.A. | Procedimiento de obtencion de un agente antiepileptico. |
| DK1667967T3 (da) | 2003-09-24 | 2012-10-08 | Ucb Pharma Sa | Fremgangsmåde til fremstilling af 2-oxo-1-pyrrolidin-derivater |
| CA2488325C (en) | 2004-11-22 | 2010-08-24 | Apotex Pharmachem Inc. | Improved process for the preparation of (s)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide and (r)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide |
| ES2441178T3 (es) | 2005-06-01 | 2014-02-03 | Ucb Pharma, S.A. | Derivados de 2-oxo-1-pirrolidina, procedimientos para prepararlos y el uso terapéutico de los mismos sobre el sistema nervioso central |
| US8338621B2 (en) | 2005-12-21 | 2012-12-25 | Ucb S.A. | Process for the preparation of 2-oxo-1-pyrrolidine derivatives |
| WO2009050735A1 (en) * | 2007-10-15 | 2009-04-23 | Lupin Limited | A novel polymorph of levetiracetam and a process for its preparation |
| EP2147911A1 (en) | 2008-07-24 | 2010-01-27 | ZaCh System S.p.A. | Process for the preparation of levetiracetam |
| US7939676B2 (en) | 2009-09-17 | 2011-05-10 | Zach System S.P.A. | Process for the preparation of levetiracetam |
| AU2015208233B2 (en) | 2014-01-21 | 2019-08-29 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
| ES2860298T3 (es) | 2014-01-21 | 2021-10-04 | Janssen Pharmaceutica Nv | Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1309692A (en) * | 1970-02-13 | 1973-03-14 | Ucb Sa | N-substituted lactams |
| GB8412358D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
| GB8412357D0 (en) * | 1984-05-15 | 1984-06-20 | Ucb Sa | Pharmaceutical composition |
-
1988
- 1988-11-23 GB GB888827389A patent/GB8827389D0/en active Pending
-
1989
- 1989-11-20 BG BG090398A patent/BG51041A3/bg unknown
- 1989-11-20 GR GR890100769A patent/GR1000719B/el not_active IP Right Cessation
- 1989-11-21 PT PT92365A patent/PT92365B/pt not_active IP Right Cessation
- 1989-11-21 GB GB8926244A patent/GB2225322B/en not_active Expired - Lifetime
- 1989-11-22 RU SU4742434A patent/RU1797607C/ru active
- 1989-11-22 PL PL89282413A patent/PL161781B1/pl unknown
- 1989-11-22 CN CN89108764A patent/CN1020604C/zh not_active Expired - Fee Related
- 1989-11-22 NO NO894649A patent/NO173823C/no unknown
- 1989-11-22 AT AT2666/89A patent/AT392781B/de not_active IP Right Cessation
- 1989-11-22 HU HU896132A patent/HU204508B/hu not_active IP Right Cessation
- 1989-11-22 FI FI895562A patent/FI91961C/fi active IP Right Grant
- 1989-11-22 ES ES8903978A patent/ES2023532A6/es not_active Expired - Lifetime
- 1989-11-23 KR KR1019890017038A patent/KR0157610B1/ko not_active Expired - Fee Related
- 1989-11-23 PH PH39568A patent/PH26332A/en unknown
-
1992
- 1992-09-05 SG SG893/92A patent/SG89392G/en unknown
- 1992-12-17 HK HK1024/92A patent/HK102492A/xx not_active IP Right Cessation
-
1993
- 1993-05-14 CY CY1672A patent/CY1672A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG89392G (en) | 1992-12-04 |
| GB2225322B (en) | 1992-03-25 |
| ES2023532A6 (es) | 1992-01-16 |
| GB2225322A (en) | 1990-05-30 |
| BG51041A3 (bg) | 1993-01-15 |
| NO894649D0 (no) | 1989-11-22 |
| HK102492A (en) | 1992-12-24 |
| NO173823B (no) | 1993-11-01 |
| PH26332A (en) | 1992-04-29 |
| PT92365A (pt) | 1990-05-31 |
| KR900007797A (ko) | 1990-06-02 |
| NO173823C (no) | 1994-02-09 |
| CN1020604C (zh) | 1993-05-12 |
| AT392781B (de) | 1991-06-10 |
| GR890100769A (en) | 1990-12-31 |
| GR1000719B (el) | 1992-11-23 |
| HU204508B (en) | 1992-01-28 |
| KR0157610B1 (ko) | 1998-11-16 |
| HU896132D0 (en) | 1990-02-28 |
| HUT53072A (en) | 1990-09-28 |
| NO894649L (no) | 1990-05-25 |
| FI895562A0 (fi) | 1989-11-22 |
| CN1042904A (zh) | 1990-06-13 |
| RU1797607C (ru) | 1993-02-23 |
| FI91961B (fi) | 1994-05-31 |
| ATA266689A (de) | 1990-11-15 |
| CY1672A (en) | 1993-05-14 |
| PT92365B (pt) | 1995-07-18 |
| FI91961C (fi) | 1994-09-12 |
| PL161781B1 (en) | 1993-07-30 |
| GB8926244D0 (en) | 1990-01-10 |
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