GB8331514D0 - Visualization method - Google Patents
Visualization methodInfo
- Publication number
- GB8331514D0 GB8331514D0 GB838331514A GB8331514A GB8331514D0 GB 8331514 D0 GB8331514 D0 GB 8331514D0 GB 838331514 A GB838331514 A GB 838331514A GB 8331514 A GB8331514 A GB 8331514A GB 8331514 D0 GB8331514 D0 GB 8331514D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- metal particles
- colloidal metal
- visualization method
- spectopho
- tometric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000007794 visualization technique Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000002923 metal particle Substances 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 238000000326 densiometry Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
- G01N33/559—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody through a gel, e.g. Ouchterlony technique
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Details Of Television Scanning (AREA)
- Communication Control (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Conductive Materials (AREA)
Abstract
A method for detecting and/or determining an agglomerate formed by the reaction between a specific binding agent and the corresponding acceptor substance according to the general methodology of blot overlay assays by using colloidal metal particles labelled components which may be visualized as a coloured signal at the surface of the blotting medium characteristic for the colloidal metal particles used or quantitatively determined following art-known spectopho- tometric procedures such as densitometry.
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838331514A GB8331514D0 (en) | 1983-11-25 | 1983-11-25 | Visualization method |
| AT84201559T ATE64468T1 (en) | 1983-11-25 | 1984-10-31 | METHODS FOR VISUAL INDICATION OF THE DIRECT OR INDIRECT DETERMINATION OF THE REACTION BETWEEN A SPECIFIC BINDING AGENT AND THE CORRESPONDING ACCEPTOR SUBSTANCE IN ''BLOT OVERLAY'' ASSAY METHODS. |
| DE8484201559T DE3484710D1 (en) | 1983-11-25 | 1984-10-31 | METHOD FOR THE OPTICAL DISPLAY OF THE DIRECT OR INDIRECT DETERMINATION OF THE REACTION BETWEEN A SPECIFIC BINDING AGENT AND THE CORRESPONDING ACCEPTOR SUBSTANCE IN "BLOT OVERLAY" TEST PROCEDURE. |
| EP84201559A EP0158746B1 (en) | 1983-11-25 | 1984-10-31 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| CA000467203A CA1253422A (en) | 1983-11-25 | 1984-11-07 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| KR1019840007168A KR890001131B1 (en) | 1983-11-25 | 1984-11-15 | Vosialization method for the direct or indirect detection of the reation between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| FI844508A FI80345C (en) | 1983-11-25 | 1984-11-16 | VISUALISERINGSFOERFARANDE FOER DIREKT ELLER INDIREKT DETEKTERING AV ETT AGGLOMERAT BILDAT AV ETT SPECIFIKT BINDANDE AEMNE OCH EN MOTSVARANDE ACCEPTORSUBSTANS VID BLOT OVERLAY-BESTAEMNINGAR OCH I DESSA BESTTAEMNINGAR |
| JP59244692A JPH0643998B2 (en) | 1983-11-25 | 1984-11-21 | Agglomeration detection and / or quantification method |
| PT79533A PT79533A (en) | 1983-11-25 | 1984-11-22 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| NO844672A NO163754C (en) | 1983-11-25 | 1984-11-23 | PROCEDURE FOR DETECTING OR DETERMINING AN AGGLOMERATED AND A METHOD FOR IMPLEMENTING THE PROCEDURE. |
| ZA849182A ZA849182B (en) | 1983-11-25 | 1984-11-23 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| AU35825/84A AU583484B2 (en) | 1983-11-25 | 1984-11-23 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| DK557684A DK160108C (en) | 1983-11-25 | 1984-11-23 | Method and equipment for direct or indirect detection of reaction between a specific binding agent and the corresponding acceptor substance |
| NZ210309A NZ210309A (en) | 1983-11-25 | 1984-11-23 | Blot-overlay immunoassay using colloidal metals |
| IL73607A IL73607A (en) | 1983-11-25 | 1984-11-23 | Detection and/or determination of antibody aggregates by immunospectrometric methods using colloidal metallic particles as indicators |
| ES537926A ES8602255A1 (en) | 1983-11-25 | 1984-11-23 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays. |
| US07/115,652 US4775636A (en) | 1983-11-25 | 1987-10-27 | Blot overlay assay using colloidal metal particles |
| JP5081149A JP2601616B2 (en) | 1983-11-25 | 1993-03-17 | Test kit |
| SG12594A SG12594G (en) | 1983-11-25 | 1994-01-26 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays. |
| HK148/94A HK14894A (en) | 1983-11-25 | 1994-02-24 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays |
| CY175994A CY1759A (en) | 1983-11-25 | 1994-07-15 | Visualization method for the direct or indirect detection of the reaction between a specific binding agent and the corresponding acceptor substance in blot overlay assays. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838331514A GB8331514D0 (en) | 1983-11-25 | 1983-11-25 | Visualization method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB8331514D0 true GB8331514D0 (en) | 1984-01-04 |
Family
ID=10552346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB838331514A Pending GB8331514D0 (en) | 1983-11-25 | 1983-11-25 | Visualization method |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4775636A (en) |
| EP (1) | EP0158746B1 (en) |
| JP (2) | JPH0643998B2 (en) |
| KR (1) | KR890001131B1 (en) |
| AT (1) | ATE64468T1 (en) |
| AU (1) | AU583484B2 (en) |
| CA (1) | CA1253422A (en) |
| CY (1) | CY1759A (en) |
| DE (1) | DE3484710D1 (en) |
| DK (1) | DK160108C (en) |
| ES (1) | ES8602255A1 (en) |
| FI (1) | FI80345C (en) |
| GB (1) | GB8331514D0 (en) |
| HK (1) | HK14894A (en) |
| IL (1) | IL73607A (en) |
| NO (1) | NO163754C (en) |
| NZ (1) | NZ210309A (en) |
| PT (1) | PT79533A (en) |
| ZA (1) | ZA849182B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079172A (en) | 1988-11-04 | 1992-01-07 | Board Of Trustees Operating Michigan State University | Method for detecting the presence of antibodies using gold-labeled antibodies and test kit |
Families Citing this family (118)
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| US5958790A (en) * | 1984-12-20 | 1999-09-28 | Nycomed Imaging As | Solid phase transverse diffusion assay |
| US5512332A (en) * | 1985-10-04 | 1996-04-30 | Immunivest Corporation | Process of making resuspendable coated magnetic particles |
| US5137827A (en) * | 1986-03-25 | 1992-08-11 | Midwest Research Technologies, Inc. | Diagnostic element for electrical detection of a binding reaction |
| US4837145A (en) * | 1986-06-09 | 1989-06-06 | Liotta Lance A | Layered immunoassay using antibodies bound to transport particles to determine the presence of an antigen |
| AU602694B2 (en) * | 1986-06-09 | 1990-10-25 | Ortho Diagnostic Systems Inc. | Improved colloidal gold membrane assay |
| AU7385387A (en) * | 1986-06-09 | 1987-12-10 | Ortho Diagnostic Systems Inc. | Immunoassay using detection of colloidal gold |
| US5514602A (en) * | 1986-06-09 | 1996-05-07 | Ortho Diagnostic Systems, Inc. | Method of producing a metal sol reagent containing colloidal metal particles |
| EP0254081A3 (en) * | 1986-06-30 | 1988-04-20 | Yuko Yoneda | Method of detecting specific protein |
| US5491098A (en) * | 1987-03-09 | 1996-02-13 | Janssen Pharmaceutica N.V. | Method for depositing metal particles on a marker |
| CA1340803C (en) * | 1987-03-09 | 1999-10-26 | Janssen Pharmaceutica N.V. | Method for depositing metal particles on a marker |
| USRE38430E1 (en) | 1987-03-27 | 2004-02-17 | Becton, Dickinson And Company | Solid phase chromatographic immunoassay |
| EP0560410B1 (en) | 1987-04-27 | 2002-10-02 | Inverness Medical Switzerland GmbH | A test device for performing specific binding assays |
| US4962023A (en) * | 1987-06-22 | 1990-10-09 | Louisiana State University, Agricultural And Mechanical College | Single incubation immuno sorbent assay method using particle labels to detect test antigen specific antibodies in presence of other antibodies |
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1984
- 1984-10-31 EP EP84201559A patent/EP0158746B1/en not_active Expired - Lifetime
- 1984-10-31 AT AT84201559T patent/ATE64468T1/en not_active IP Right Cessation
- 1984-10-31 DE DE8484201559T patent/DE3484710D1/en not_active Expired - Lifetime
- 1984-11-07 CA CA000467203A patent/CA1253422A/en not_active Expired
- 1984-11-15 KR KR1019840007168A patent/KR890001131B1/en not_active Expired
- 1984-11-16 FI FI844508A patent/FI80345C/en active IP Right Grant
- 1984-11-21 JP JP59244692A patent/JPH0643998B2/en not_active Expired - Lifetime
- 1984-11-22 PT PT79533A patent/PT79533A/en unknown
- 1984-11-23 DK DK557684A patent/DK160108C/en not_active IP Right Cessation
- 1984-11-23 NZ NZ210309A patent/NZ210309A/en unknown
- 1984-11-23 NO NO844672A patent/NO163754C/en not_active IP Right Cessation
- 1984-11-23 IL IL73607A patent/IL73607A/en not_active IP Right Cessation
- 1984-11-23 AU AU35825/84A patent/AU583484B2/en not_active Expired
- 1984-11-23 ES ES537926A patent/ES8602255A1/en not_active Expired
- 1984-11-23 ZA ZA849182A patent/ZA849182B/en unknown
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1987
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1994
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079172A (en) | 1988-11-04 | 1992-01-07 | Board Of Trustees Operating Michigan State University | Method for detecting the presence of antibodies using gold-labeled antibodies and test kit |
Also Published As
| Publication number | Publication date |
|---|---|
| FI80345B (en) | 1990-01-31 |
| ES537926A0 (en) | 1985-11-01 |
| PT79533A (en) | 1984-12-01 |
| KR850003728A (en) | 1985-06-26 |
| FI844508L (en) | 1985-05-26 |
| DK160108B (en) | 1991-01-28 |
| ES8602255A1 (en) | 1985-11-01 |
| JPS60185160A (en) | 1985-09-20 |
| ZA849182B (en) | 1986-06-25 |
| FI844508A0 (en) | 1984-11-16 |
| DK160108C (en) | 1995-07-24 |
| EP0158746A3 (en) | 1987-09-23 |
| DK557684D0 (en) | 1984-11-23 |
| NZ210309A (en) | 1987-04-30 |
| AU583484B2 (en) | 1989-05-04 |
| JPH0643162A (en) | 1994-02-18 |
| FI80345C (en) | 1992-11-16 |
| NO163754C (en) | 1993-01-12 |
| IL73607A0 (en) | 1985-02-28 |
| DK557684A (en) | 1985-05-26 |
| IL73607A (en) | 1988-12-30 |
| DE3484710D1 (en) | 1991-07-18 |
| EP0158746B1 (en) | 1991-06-12 |
| AU3582584A (en) | 1985-05-30 |
| CA1253422A (en) | 1989-05-02 |
| HK14894A (en) | 1994-03-04 |
| ATE64468T1 (en) | 1991-06-15 |
| KR890001131B1 (en) | 1989-04-24 |
| NO163754B (en) | 1990-04-02 |
| JP2601616B2 (en) | 1997-04-16 |
| US4775636A (en) | 1988-10-04 |
| CY1759A (en) | 1994-07-15 |
| EP0158746A2 (en) | 1985-10-23 |
| JPH0643998B2 (en) | 1994-06-08 |
| NO844672L (en) | 1985-05-28 |
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