GB838759A - 5-(ú¤-substituted-phenoxy-methyl)-2-oxazolidone compounds and their preparation - Google Patents
5-(ú¤-substituted-phenoxy-methyl)-2-oxazolidone compounds and their preparationInfo
- Publication number
- GB838759A GB838759A GB16615/58A GB1661558A GB838759A GB 838759 A GB838759 A GB 838759A GB 16615/58 A GB16615/58 A GB 16615/58A GB 1661558 A GB1661558 A GB 1661558A GB 838759 A GB838759 A GB 838759A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- preparation
- phenoxy
- substituted
- oxazolid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 abstract 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical class CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000881 depressing effect Effects 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 o - tolyloxy - methyl Chemical group 0.000 abstract 1
- 239000008188 pellet Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 235000013772 propylene glycol Nutrition 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
The invention comprises 5-(o-methoxyphenoxymethyl)- and 5-(o-tolyloxymethyl)-oxazolid-2-one, and the preparation thereof by reacting the corresponding substituted propane-1,2-diols with urethane in the presence of a metallic alcoholate.ALSO:Pharmaceutical compositions comprise 5-(o-methoxyphenoxymethyl) - or 5 - (o - tolyloxy - methyl)-oxazolid-2-one in admixture with an inert carrier, for example, a 1% sodium carboxymethyl cellulose solution. They may be used in any of the pharmaceutical forms employed for oral administration, for example capsules, granules, pellets, pills, powders, suspensions, solutions and tablets. The compositions are central relaxing agents having a depressing action.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH838759X | 1957-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB838759A true GB838759A (en) | 1960-06-22 |
Family
ID=4540995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB16615/58A Expired GB838759A (en) | 1957-06-11 | 1958-05-23 | 5-(ú¤-substituted-phenoxy-methyl)-2-oxazolidone compounds and their preparation |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB838759A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3251836A (en) * | 1961-09-26 | 1966-05-17 | Szabo Hnos Kessler & Cia S R L | Oxazolidone derivatives and their preparation |
-
1958
- 1958-05-23 GB GB16615/58A patent/GB838759A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3251836A (en) * | 1961-09-26 | 1966-05-17 | Szabo Hnos Kessler & Cia S R L | Oxazolidone derivatives and their preparation |
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