GB681904A - Solutions of thiosemicarbazones - Google Patents
Solutions of thiosemicarbazonesInfo
- Publication number
- GB681904A GB681904A GB1150749A GB1150749A GB681904A GB 681904 A GB681904 A GB 681904A GB 1150749 A GB1150749 A GB 1150749A GB 1150749 A GB1150749 A GB 1150749A GB 681904 A GB681904 A GB 681904A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- water
- thiosemicarbazones
- solutions
- methylacetamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940042396 direct acting antivirals thiosemicarbazones Drugs 0.000 title abstract 4
- 150000003584 thiosemicarbazones Chemical class 0.000 title abstract 4
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 4
- -1 glycol ethers Chemical class 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- OHLUUHNLEMFGTQ-UHFFFAOYSA-N N-methylacetamide Chemical compound CNC(C)=O OHLUUHNLEMFGTQ-UHFFFAOYSA-N 0.000 abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- 150000002334 glycols Chemical class 0.000 abstract 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 2
- AFINAILKDBCXMX-PBHICJAKSA-N (2s,3r)-2-amino-3-hydroxy-n-(4-octylphenyl)butanamide Chemical compound CCCCCCCCC1=CC=C(NC(=O)[C@@H](N)[C@@H](C)O)C=C1 AFINAILKDBCXMX-PBHICJAKSA-N 0.000 abstract 1
- 150000008431 aliphatic amides Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- HUMNYLRZRPPJDN-KWCOIAHCSA-N benzaldehyde Chemical group O=[11CH]C1=CC=CC=C1 HUMNYLRZRPPJDN-KWCOIAHCSA-N 0.000 abstract 1
- 150000003935 benzaldehydes Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Thiosemicarbazones are dissolved in water-miscible aliphatic amides containing if necessary some water. Solutions are described of the thiosemicarbazones derived from the 4-acetylamino-, 4-amino-, 4-propionylamino-, 4-benzoyl-amino-, 4-methoxy-, 4-allyloxy-, anisal-4-amino-, and phosphoric acid derivative of 4-amino-benzaldehydes (see Specification 680,142). The solubilities of the latter compounds in formamide and methylacetamide/water are given. Mixtures of the above solvents with glycols and glycol ethers as in Specification 681,905 may be used.ALSO:Solutions of a number of thiosemicarbazones of benzaldehyde derivatives in water-miscible amides of aliphatic acids such as formamide and methylacetamide with water where necessary and mixed if desired, with glycols or glycol ethers (see Specification 681,905) are made for therapeutic use. Substituents in the benzaldehyde residue include amino substituted amino, alkoxy, and a phosphoric acid compound (see Specification 680,142, [Group IV (b)].
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1949P0035247 DE858127C (en) | 1949-04-26 | 1949-04-26 | Process for the preparation of solutions of thiosemicarbazones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB681904A true GB681904A (en) | 1952-10-29 |
Family
ID=40019334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1150749A Expired GB681904A (en) | 1949-04-26 | 1949-04-29 | Solutions of thiosemicarbazones |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE858127C (en) |
| GB (1) | GB681904A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2837509A (en) * | 1953-05-26 | 1958-06-03 | Lasdon Foundation Inc | Thiosemicarbazone compounds |
| WO2007051249A1 (en) * | 2005-11-03 | 2007-05-10 | A & C Chemicals Pty Ltd | Seed dressing |
-
1949
- 1949-04-26 DE DE1949P0035247 patent/DE858127C/en not_active Expired
- 1949-04-29 GB GB1150749A patent/GB681904A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2837509A (en) * | 1953-05-26 | 1958-06-03 | Lasdon Foundation Inc | Thiosemicarbazone compounds |
| WO2007051249A1 (en) * | 2005-11-03 | 2007-05-10 | A & C Chemicals Pty Ltd | Seed dressing |
Also Published As
| Publication number | Publication date |
|---|---|
| DE858127C (en) | 1952-12-04 |
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