GB2530521B - Mass spectral analysis of patient samples for the detection of the human chorionic gonadotropin - Google Patents
Mass spectral analysis of patient samples for the detection of the human chorionic gonadotropin Download PDFInfo
- Publication number
- GB2530521B GB2530521B GB1416868.6A GB201416868A GB2530521B GB 2530521 B GB2530521 B GB 2530521B GB 201416868 A GB201416868 A GB 201416868A GB 2530521 B GB2530521 B GB 2530521B
- Authority
- GB
- United Kingdom
- Prior art keywords
- detection
- spectral analysis
- mass spectral
- patient samples
- chorionic gonadotropin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 102000011022 Chorionic Gonadotropin Human genes 0.000 title 1
- 108010062540 Chorionic Gonadotropin Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 229940084986 human chorionic gonadotropin Drugs 0.000 title 1
- 239000013610 patient sample Substances 0.000 title 1
- 238000010183 spectrum analysis Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1416868.6A GB2530521B (en) | 2014-09-24 | 2014-09-24 | Mass spectral analysis of patient samples for the detection of the human chorionic gonadotropin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1416868.6A GB2530521B (en) | 2014-09-24 | 2014-09-24 | Mass spectral analysis of patient samples for the detection of the human chorionic gonadotropin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB201416868D0 GB201416868D0 (en) | 2014-11-05 |
| GB2530521A GB2530521A (en) | 2016-03-30 |
| GB2530521B true GB2530521B (en) | 2020-06-10 |
Family
ID=51869420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1416868.6A Active GB2530521B (en) | 2014-09-24 | 2014-09-24 | Mass spectral analysis of patient samples for the detection of the human chorionic gonadotropin |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2530521B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201808529D0 (en) * | 2018-05-24 | 2018-07-11 | Binding Site Group Ltd | Identification of immunoglobulins usong mass spectrometry |
| CN115684606B (en) * | 2022-10-21 | 2023-11-28 | 南方医科大学珠江医院 | M protein detection method |
| CN116519778A (en) * | 2023-03-29 | 2023-08-01 | 上海交通大学 | A Dried Serum Tablet-Based Cancer Metabolic Diagnosis Device and Its Performance Evaluation Method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2702494A1 (en) * | 1993-03-11 | 1994-09-16 | Lafon Labor | Kit for the diagnosis of a cancer secreting hCG or fragments of hCG and vaccine intended for the immunotherapy of such a cancer |
| WO2006099126A2 (en) * | 2005-03-11 | 2006-09-21 | Ciphergen Biosystems, Inc. | Biomarkers for ovarian cancer and endometrial cancer: hepcidin |
| US20090159793A1 (en) * | 2007-12-21 | 2009-06-25 | Hanas Jay S | Identification of biomarkers in biological samples and methods of using same |
| WO2009138392A1 (en) * | 2008-05-14 | 2009-11-19 | ETH Zürich | Method for biomarker and drug-target discovery for prostate cancer diagnosis and treatment as well as biomarker assays determined therewith |
-
2014
- 2014-09-24 GB GB1416868.6A patent/GB2530521B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2702494A1 (en) * | 1993-03-11 | 1994-09-16 | Lafon Labor | Kit for the diagnosis of a cancer secreting hCG or fragments of hCG and vaccine intended for the immunotherapy of such a cancer |
| WO2006099126A2 (en) * | 2005-03-11 | 2006-09-21 | Ciphergen Biosystems, Inc. | Biomarkers for ovarian cancer and endometrial cancer: hepcidin |
| US20090159793A1 (en) * | 2007-12-21 | 2009-06-25 | Hanas Jay S | Identification of biomarkers in biological samples and methods of using same |
| WO2009138392A1 (en) * | 2008-05-14 | 2009-11-19 | ETH Zürich | Method for biomarker and drug-target discovery for prostate cancer diagnosis and treatment as well as biomarker assays determined therewith |
Non-Patent Citations (4)
| Title |
|---|
| Analytical and Bioanalytical Chemistry, vol. 405 issue 5, 2013, Lund et al, 'Sports drug testing using immuno-MS...' pp. 1569-1576 * |
| Clinical Chemistry, vol. 60 issue 8, 2014, Woldemariam et al, 'Immunoextraction-tandem mass spectrometry method...' pp. 1089-1097 * |
| International Journal of Gynecology & Obstetrics, Vol. 60 No. 1, 1998, Nishimura et al., "Molecular heterogeneity of hCG beta-related glycoproteins and the clinical relevance in trophoblastic and non-trophoblastic tumours" pages 29-32. * |
| Tumor Biology, vol. 35, 2014, Lund et al, 'Epitope analysis and detection of human chorionic gonadotropin (hCG) variants...' pp. 1013-1022 * |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2530521A (en) | 2016-03-30 |
| GB201416868D0 (en) | 2014-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) |
Free format text: REGISTERED BETWEEN 20160503 AND 20160504 |
|
| 732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) |
Free format text: REGISTERED BETWEEN 20240829 AND 20240904 |