[go: up one dir, main page]

GB2586201B - A stable powder formulation of racecadotril - Google Patents

A stable powder formulation of racecadotril Download PDF

Info

Publication number
GB2586201B
GB2586201B GB1906754.5A GB201906754A GB2586201B GB 2586201 B GB2586201 B GB 2586201B GB 201906754 A GB201906754 A GB 201906754A GB 2586201 B GB2586201 B GB 2586201B
Authority
GB
United Kingdom
Prior art keywords
racecadotril
powder formulation
stable powder
stable
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1906754.5A
Other versions
GB201906754D0 (en
GB2586201A (en
Inventor
Patel Hetalbahen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orbit Pharmaceuticals
Original Assignee
Orbit Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orbit Pharmaceuticals filed Critical Orbit Pharmaceuticals
Priority to GB1906754.5A priority Critical patent/GB2586201B/en
Publication of GB201906754D0 publication Critical patent/GB201906754D0/en
Publication of GB2586201A publication Critical patent/GB2586201A/en
Application granted granted Critical
Publication of GB2586201B publication Critical patent/GB2586201B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
GB1906754.5A 2019-05-14 2019-05-14 A stable powder formulation of racecadotril Active GB2586201B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1906754.5A GB2586201B (en) 2019-05-14 2019-05-14 A stable powder formulation of racecadotril

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1906754.5A GB2586201B (en) 2019-05-14 2019-05-14 A stable powder formulation of racecadotril

Publications (3)

Publication Number Publication Date
GB201906754D0 GB201906754D0 (en) 2019-06-26
GB2586201A GB2586201A (en) 2021-02-17
GB2586201B true GB2586201B (en) 2023-05-24

Family

ID=67384606

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1906754.5A Active GB2586201B (en) 2019-05-14 2019-05-14 A stable powder formulation of racecadotril

Country Status (1)

Country Link
GB (1) GB2586201B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114469873B (en) * 2022-01-20 2023-01-31 首都医科大学附属北京儿童医院 Pharmaceutical preparation containing racecadotril and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2247163T3 (en) * 2000-06-23 2006-03-01 Bioprojet DRY POWDER FORMULATION THAT RACEDOTRIL INCLUDES.
CN102166197B (en) * 2011-04-25 2012-09-05 四川百利药业有限责任公司 Racecadotril granules and production process thereof
CN106822907B (en) * 2016-12-29 2021-02-09 山东达因海洋生物制药股份有限公司 Two-phase release preparation containing racecadotril and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
GB201906754D0 (en) 2019-06-26
GB2586201A (en) 2021-02-17

Similar Documents

Publication Publication Date Title
IL279464B2 (en) Pharmaceutical formulation of odevixibat
IL273947A (en) Formulations of a compound modulating kinases
PT3795137T (en) Electrostatically sprayable cosmetic formulation
GB201912505D0 (en) Pharmaceutical formulation
IL292682A (en) Oral formulation of x842
SG11202010124SA (en) Stable pharmaceutical formulation
SI3582617T1 (en) Stable formulation of pesticidal pyridazinpyrazolamides
GB2586201B (en) A stable powder formulation of racecadotril
PL422716A1 (en) Inhaler of a single dose of dry powder
IL283593A (en) Oral formulations of branaplam
IL289927A (en) New pharmaceutical formulation
PL4062913T3 (en) Solid oral formulation of utidelone
GB201909280D0 (en) Solid dose formulation
PT4003297T (en) New formulations of amisulpride
EP3687539A4 (en) Stable pharmaceutical compositions of dalfampridine
PT3943070T (en) Long-acting formulations of bedaquiline
GB202311000D0 (en) Powder dispenser
IL253788A0 (en) Pharmaceutical formulation of racecadotril
HK40060761A (en) Formulations of a compound and uses thereof
IL313482A (en) Stable formulations of shr0302
GB201919441D0 (en) A dietary composition comprising an ingredient of interest
HK40081024A (en) Oral formulation of x842
GB202318641D0 (en) Powder dispensers
SG11202110767VA (en) Increasing stability of lc-pufa
GB202404186D0 (en) Highly loaded metalaxyl-m formulations

Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)
S20A Reinstatement of application (sect. 20a/patents act 1977)

Free format text: REQUEST FOR REINSTATEMENT FILED

Effective date: 20220317

S20A Reinstatement of application (sect. 20a/patents act 1977)

Free format text: REQUEST FOR REINSTATEMENT ALLOWED

Effective date: 20220624

732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)

Free format text: REGISTERED BETWEEN 20250605 AND 20250611