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GB2580356B - Cell processing unit, cell processing system and methods of use thereof - Google Patents

Cell processing unit, cell processing system and methods of use thereof Download PDF

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Publication number
GB2580356B
GB2580356B GB1900107.2A GB201900107A GB2580356B GB 2580356 B GB2580356 B GB 2580356B GB 201900107 A GB201900107 A GB 201900107A GB 2580356 B GB2580356 B GB 2580356B
Authority
GB
United Kingdom
Prior art keywords
cell processing
methods
processing unit
processing system
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB1900107.2A
Other versions
GB2580356A (en
Inventor
Singh Veraitch Farlan
Collings Simon
Brown Nicholas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oribiotech Ltd
Original Assignee
Oribiotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB1900107.2A priority Critical patent/GB2580356B/en
Application filed by Oribiotech Ltd filed Critical Oribiotech Ltd
Priority to EP20700318.7A priority patent/EP3906298A1/en
Priority to US17/419,182 priority patent/US20220098536A1/en
Priority to JP2021539028A priority patent/JP2022516325A/en
Priority to CA3125253A priority patent/CA3125253A1/en
Priority to JP2021539029A priority patent/JP7659823B2/en
Priority to AU2020204795A priority patent/AU2020204795A1/en
Priority to EP20700316.1A priority patent/EP3906296A1/en
Priority to AU2020204794A priority patent/AU2020204794A1/en
Priority to PCT/GB2020/050009 priority patent/WO2020141327A1/en
Priority to JP2021539027A priority patent/JP2022516324A/en
Priority to EP20700317.9A priority patent/EP3906297A1/en
Priority to US17/419,196 priority patent/US20220064580A1/en
Priority to CN202080007586.8A priority patent/CN113396209A/en
Priority to CA3125256A priority patent/CA3125256A1/en
Priority to US17/419,169 priority patent/US12365858B2/en
Priority to KR1020217024068A priority patent/KR20210111794A/en
Priority to PCT/GB2020/050008 priority patent/WO2020141326A1/en
Priority to AU2020204975A priority patent/AU2020204975A1/en
Priority to US17/419,206 priority patent/US20220073854A1/en
Priority to KR1020217023618A priority patent/KR20210111266A/en
Priority to PCT/GB2020/050010 priority patent/WO2020141328A1/en
Priority to KR1020217024345A priority patent/KR20210111796A/en
Priority to CN202080007625.4A priority patent/CN113396211A/en
Priority to EP20700315.3A priority patent/EP3906295A1/en
Priority to JP2021539030A priority patent/JP2022516186A/en
Priority to AU2020205031A priority patent/AU2020205031B2/en
Priority to CN202080007585.3A priority patent/CN113396208A/en
Priority to PCT/GB2020/050007 priority patent/WO2020141325A1/en
Priority to CA3125254A priority patent/CA3125254A1/en
Priority to CN202080007624.XA priority patent/CN113396210A/en
Priority to CA3125250A priority patent/CA3125250A1/en
Priority to US16/735,626 priority patent/US12024699B2/en
Publication of GB2580356A publication Critical patent/GB2580356A/en
Priority to IL284464A priority patent/IL284464A/en
Priority to IL284467A priority patent/IL284467A/en
Priority to IL284469A priority patent/IL284469A/en
Application granted granted Critical
Publication of GB2580356B publication Critical patent/GB2580356B/en
Priority to JP2024177186A priority patent/JP2025016499A/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/10—Apparatus for enzymology or microbiology rotatably mounted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/005—Incubators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/46—Means for fastening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/48—Holding appliances; Racks; Supports
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/50—Means for positioning or orientating the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/04—Tissue, human, animal or plant cell, or virus culture apparatus with means providing thin layers
    • C12M3/043—Tissue, human, animal or plant cell, or virus culture apparatus with means providing thin layers rotatably mounted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M43/00—Combinations of bioreactors or fermenters with other apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
GB1900107.2A 2019-01-04 2019-01-04 Cell processing unit, cell processing system and methods of use thereof Active GB2580356B (en)

Priority Applications (37)

Application Number Priority Date Filing Date Title
GB1900107.2A GB2580356B (en) 2019-01-04 2019-01-04 Cell processing unit, cell processing system and methods of use thereof
PCT/GB2020/050010 WO2020141328A1 (en) 2019-01-04 2020-01-03 Cell processing platform cell processing system and methods of use thereof
JP2021539028A JP2022516325A (en) 2019-01-04 2020-01-03 Cell processing devices, cell processing systems, and methods of using them
CA3125253A CA3125253A1 (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system and methods of use thereof
JP2021539029A JP7659823B2 (en) 2019-01-04 2020-01-03 CELL PROCESSING UNIT, CELL PROCESSING SYSTEM AND METHOD OF USING SAME - Patent application
AU2020204795A AU2020204795A1 (en) 2019-01-04 2020-01-03 Cell processing platform cell processing system and methods of use thereof
EP20700316.1A EP3906296A1 (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system and methods of use thereof
AU2020204794A AU2020204794A1 (en) 2019-01-04 2020-01-03 Cell processing device cell processing system and methods of use thereof
PCT/GB2020/050009 WO2020141327A1 (en) 2019-01-04 2020-01-03 Cell processing device cell processing system and methods of use thereof
JP2021539027A JP2022516324A (en) 2019-01-04 2020-01-03 Cell processing platform, cell processing system, and how to use it
EP20700317.9A EP3906297A1 (en) 2019-01-04 2020-01-03 Cell processing device cell processing system and methods of use thereof
US17/419,196 US20220064580A1 (en) 2019-01-04 2020-01-03 Cell processing device cell processing system and methods of use thereof
CN202080007586.8A CN113396209A (en) 2019-01-04 2020-01-03 Cell processing apparatus, cell processing system, and method of using the same
CA3125256A CA3125256A1 (en) 2019-01-04 2020-01-03 Cell processing platform cell processing system and methods of use thereof
US17/419,169 US12365858B2 (en) 2019-01-04 2020-01-03 Cell processing unit, cell processing system and methods of use thereof
KR1020217024068A KR20210111794A (en) 2019-01-04 2020-01-03 Cell processing apparatus, cell processing system and method of use thereof
PCT/GB2020/050008 WO2020141326A1 (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system and methods of use thereof
AU2020204975A AU2020204975A1 (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system and methods of use thereof
EP20700318.7A EP3906298A1 (en) 2019-01-04 2020-01-03 Cell processing platform cell processing system and methods of use thereof
KR1020217023618A KR20210111266A (en) 2019-01-04 2020-01-03 Cell processing units, cell processing systems and methods of use thereof
CN202080007625.4A CN113396211A (en) 2019-01-04 2020-01-03 Cell processing unit, cell processing system and method of using the same
US17/419,182 US20220098536A1 (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system and methods of use thereof
KR1020217024345A KR20210111796A (en) 2019-01-04 2020-01-03 Cell processing platforms, cell processing systems and methods of use thereof
EP20700315.3A EP3906295A1 (en) 2019-01-04 2020-01-03 Cell processing unit, cell processing system and methods of use thereof
JP2021539030A JP2022516186A (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system, and how to use it
AU2020205031A AU2020205031B2 (en) 2019-01-04 2020-01-03 Cell processing unit, cell processing system and methods of use thereof
CN202080007585.3A CN113396208A (en) 2019-01-04 2020-01-03 Cell processing platform, cell processing system and use method thereof
PCT/GB2020/050007 WO2020141325A1 (en) 2019-01-04 2020-01-03 Cell processing unit, cell processing system and methods of use thereof
CA3125254A CA3125254A1 (en) 2019-01-04 2020-01-03 Cell processing device cell processing system and methods of use thereof
CN202080007624.XA CN113396210A (en) 2019-01-04 2020-01-03 Cell processing container, cell processing system and method of using the same
CA3125250A CA3125250A1 (en) 2019-01-04 2020-01-03 Cell processing unit, cell processing system and methods of use thereof
US17/419,206 US20220073854A1 (en) 2019-01-04 2020-01-03 Cell processing platform cell processing system and methods of use thereof
US16/735,626 US12024699B2 (en) 2019-01-04 2020-01-06 Systems, devices, and methods for cell processing
IL284464A IL284464A (en) 2019-01-04 2021-06-29 Cell processing unit, cell processing system and methods of use thereof
IL284467A IL284467A (en) 2019-01-04 2021-06-29 Cell processing device, cell processing system and methods of use thereof
IL284469A IL284469A (en) 2019-01-04 2021-06-29 Cell processing platform cell processing system and methods of use thereof
JP2024177186A JP2025016499A (en) 2019-01-04 2024-10-09 CELL PROCESSING UNIT, CELL PROCESSING SYSTEM AND METHOD OF USING SAME - Patent application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1900107.2A GB2580356B (en) 2019-01-04 2019-01-04 Cell processing unit, cell processing system and methods of use thereof

Publications (2)

Publication Number Publication Date
GB2580356A GB2580356A (en) 2020-07-22
GB2580356B true GB2580356B (en) 2022-08-31

Family

ID=71124556

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1900107.2A Active GB2580356B (en) 2019-01-04 2019-01-04 Cell processing unit, cell processing system and methods of use thereof

Country Status (1)

Country Link
GB (1) GB2580356B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202003403D0 (en) * 2020-03-09 2020-04-22 Oribiotech Ltd A system for cell processing
WO2023037086A1 (en) * 2021-09-08 2023-03-16 Oribiotech Ltd Sampling consumable for sampling a fluid from a bioreactor
CN114149918A (en) * 2021-11-29 2022-03-08 深圳中旭生物科技有限公司 Methods and compositions for binding NK immune cells
GB2624632A (en) * 2022-11-22 2024-05-29 Oribiotech Ltd Sampling module for a bioreactor container

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040149776A1 (en) * 2003-01-21 2004-08-05 Ilya Feygin Rotary-drive dispenser
WO2010024906A1 (en) * 2008-08-26 2010-03-04 Wako Pure Chemical Industries, Ltd. Disposable device for automated biological sample preparation
WO2018087558A1 (en) * 2016-11-11 2018-05-17 Oribiotech Ltd Cell culture device system and methods of use thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040149776A1 (en) * 2003-01-21 2004-08-05 Ilya Feygin Rotary-drive dispenser
WO2010024906A1 (en) * 2008-08-26 2010-03-04 Wako Pure Chemical Industries, Ltd. Disposable device for automated biological sample preparation
WO2018087558A1 (en) * 2016-11-11 2018-05-17 Oribiotech Ltd Cell culture device system and methods of use thereof

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