GB2543713B - Polymeric proteins and uses thereof - Google Patents

Polymeric proteins and uses thereof

Info

Publication number: GB2543713B
Authority: GB; United Kingdom
Prior art keywords: polymeric proteins; proteins; polymeric
Prior art date: 2014-07-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

GB1702637.8A

Other versions

GB201702637D0 (en

GB2543713A (en

Inventor

Pleass Richard

Blundell Patricia

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Liverpool School of Tropical Medicine

Original Assignee

Liverpool School of Tropical Medicine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-07-18

Filing date

2015-07-20

Publication date

2019-03-27

2015-07-20 Application filed by Liverpool School of Tropical Medicine filed Critical Liverpool School of Tropical Medicine

2017-04-05 Publication of GB201702637D0 publication Critical patent/GB201702637D0/en

2017-04-26 Publication of GB2543713A publication Critical patent/GB2543713A/en

2019-03-27 Application granted granted Critical

2019-03-27 Publication of GB2543713B publication Critical patent/GB2543713B/en

Status Active legal-status Critical Current

2035-07-20 Anticipated expiration legal-status Critical

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

GB1702637.8A 2014-07-18 2015-07-20 Polymeric proteins and uses thereof Active GB2543713B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB1412821.9A GB201412821D0 (en)	2014-07-18	2014-07-18	Polymeric proteins and uses thereof
PCT/GB2015/052098 WO2016009232A1 (en)	2014-07-18	2015-07-20	Polymeric proteins and uses thereof

Publications (3)

Publication Number	Publication Date
GB201702637D0 GB201702637D0 (en)	2017-04-05
GB2543713A GB2543713A (en)	2017-04-26
GB2543713B true GB2543713B (en)	2019-03-27

Family

ID=51494824

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
GBGB1412821.9A Ceased GB201412821D0 (en)	2014-07-18	2014-07-18	Polymeric proteins and uses thereof
GB1702637.8A Active GB2543713B (en)	2014-07-18	2015-07-20	Polymeric proteins and uses thereof

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
GBGB1412821.9A Ceased GB201412821D0 (en)	2014-07-18	2014-07-18	Polymeric proteins and uses thereof

Country Status (2)

Country	Link
GB (2)	GB201412821D0 (en)
WO (1)	WO2016009232A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX394116B (en)	2015-07-24	2025-03-19	Gliknik Inc	FUSION PROTEINS OF HUMAN PROTEIN FRAGMENTS TO CREATE ORDERED MULTIMERIZED IMMUNOGLOBULIN FC COMPOSITIONS WITH ENHANCED COMPLEMENT BINDING.
AU2017279538A1 (en)	2016-06-07	2019-01-03	Gliknik Inc.	Cysteine-optimized stradomers
EP3487534A4 (en)	2016-07-22	2020-03-25	Gliknik Inc.	Fusion proteins of human protein fragments to create orderly multimerized immunoglobulin fc compositions with enhanced fc receptor binding
CN110022898B (en)	2016-12-09	2023-07-04	格利克尼克股份有限公司	Methods of treating inflammatory diseases with multivalent Fc compounds
CN112236449A (en) *	2018-03-16	2021-01-15	利物浦热带医学院	Chimeric FC receptor binding proteins and uses thereof
CN116769042A (en) *	2021-06-17	2023-09-19	东莞市朋志生物科技有限公司	Chimeric immunoglobulins

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011073692A1 (en) *	2009-12-18	2011-06-23	The University Of Nottingham	Proteins, nucleic acid molecules and compositions

2014
- 2014-07-18 GB GBGB1412821.9A patent/GB201412821D0/en not_active Ceased
2015
- 2015-07-20 WO PCT/GB2015/052098 patent/WO2016009232A1/en not_active Ceased
- 2015-07-20 GB GB1702637.8A patent/GB2543713B/en active Active

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011073692A1 (en) *	2009-12-18	2011-06-23	The University Of Nottingham	Proteins, nucleic acid molecules and compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
COLOMA M J, CLIFT A, WIMS L, MORRISON S L: "The role of carbohydrate in the assembly and function of polymeric IgG.", MOLECULAR IMMUNOLOGY., PERGAMON, GB, vol. 37, no. 18, 1 December 2000 (2000-12-01), GB, pages 1081 - 1090, XP002745729, ISSN: 0161-5890, DOI: 10.1016/S0161-5890(01)00024-4 *
Nature Biotech., Vol.12, 1994, Smith, R. I. et al., "Recombinant polymeric IgG...", pp.683-688 *

Also Published As

Publication number	Publication date
GB201702637D0 (en)	2017-04-05
GB2543713A (en)	2017-04-26
GB201412821D0 (en)	2014-09-03
WO2016009232A1 (en)	2016-01-21

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