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GB2376024B - The production method of transgenic porcine producing human eryhropoietin and the transgenic porcine - Google Patents

The production method of transgenic porcine producing human eryhropoietin and the transgenic porcine

Info

Publication number
GB2376024B
GB2376024B GB0220971A GB0220971A GB2376024B GB 2376024 B GB2376024 B GB 2376024B GB 0220971 A GB0220971 A GB 0220971A GB 0220971 A GB0220971 A GB 0220971A GB 2376024 B GB2376024 B GB 2376024B
Authority
GB
United Kingdom
Prior art keywords
transgenic porcine
eryhropoietin
production method
producing human
porcine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0220971A
Other versions
GB2376024A (en
GB0220971D0 (en
Inventor
Won-Kyong Chang
Jin-Gi Park
Hwan-Hoo Seong
Kwan-Sik Min
Bo-Seok Yang
Gi-Sun Im
Yun-Keun Lee
Chang-Hyun Lee
Jin-Hoei Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
REPUBLIC KOREA
Original Assignee
REPUBLIC KOREA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by REPUBLIC KOREA filed Critical REPUBLIC KOREA
Publication of GB0220971D0 publication Critical patent/GB0220971D0/en
Publication of GB2376024A publication Critical patent/GB2376024A/en
Application granted granted Critical
Publication of GB2376024B publication Critical patent/GB2376024B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25B—TOOLS OR BENCH DEVICES NOT OTHERWISE PROVIDED FOR, FOR FASTENING, CONNECTING, DISENGAGING OR HOLDING
    • B25B21/00—Portable power-driven screw or nut setting or loosening tools; Attachments for drilling apparatus serving the same purpose
    • B25B21/02—Portable power-driven screw or nut setting or loosening tools; Attachments for drilling apparatus serving the same purpose with means for imparting impact to screwdriver blade or nut socket
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60B—VEHICLE WHEELS; CASTORS; AXLES FOR WHEELS OR CASTORS; INCREASING WHEEL ADHESION
    • B60B29/00—Apparatus or tools for mounting or dismounting wheels
    • B60B29/003—Wrenches, e.g. of the ratchet type
    • B60B29/006—Wrenches, e.g. of the ratchet type with electric or pneumatic drive
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB0220971A 2000-02-14 2000-06-28 The production method of transgenic porcine producing human eryhropoietin and the transgenic porcine Expired - Fee Related GB2376024B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020000006888A KR100358754B1 (en) 2000-02-14 2000-02-14 The production method of transgenic porcine producing human erythropoietin and the transgenic porcine
PCT/KR2000/000675 WO2001059074A1 (en) 2000-02-14 2000-06-28 The production method of transgenic porcine producing human erythropoietin and the transgenic porcine

Publications (3)

Publication Number Publication Date
GB0220971D0 GB0220971D0 (en) 2002-10-23
GB2376024A GB2376024A (en) 2002-12-04
GB2376024B true GB2376024B (en) 2004-09-22

Family

ID=19646330

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0220971A Expired - Fee Related GB2376024B (en) 2000-02-14 2000-06-28 The production method of transgenic porcine producing human eryhropoietin and the transgenic porcine

Country Status (4)

Country Link
KR (1) KR100358754B1 (en)
AU (1) AU2000255759A1 (en)
GB (1) GB2376024B (en)
WO (1) WO2001059074A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100453571B1 (en) * 2001-07-24 2004-10-20 대한민국 Transgenic porcine capable of producing human erythropoietin and preparation method thereof
CN1283785C (en) * 2002-05-20 2006-11-08 上海杰隆生物工程股份有限公司 Method of producing human forcing erythrogenin using transgene animal mammary gland
GB0322196D0 (en) * 2003-09-23 2003-10-22 Cxr Biosciences Ltd Excretable reporter systems
WO2005077404A1 (en) 2004-02-13 2005-08-25 Stem Cell Therapeutics Corp. Use of luteinizing hormone (lh) and chorionic gonadotropin (hcg) for proliferation of neural stem cells and neurogenesis
JP2008527980A (en) * 2005-01-25 2008-07-31 アポロ ライフ サイエンシズ リミテッド Molecule and its chimeric molecule
KR100769291B1 (en) * 2006-02-13 2007-10-24 조아제약주식회사 Mammary gland specific human erythropoietin expression vector, transgenic animal using the same and method for producing human erythropoietin using the same
CA2643502A1 (en) * 2006-03-17 2007-09-27 Stem Cell Therapeutics Corp. Dosing regimes for lh or hcg and epo for treatment of neurological disorders
KR100935335B1 (en) * 2007-09-12 2010-01-07 차의과학대학교 산학협력단 In Vivo Production of Hematopoietic Cells Using Immunosuppressed Erythropoietin-Producing Transgenic Pigs and Animal Bioreactor for Hematopoietic Cell Proliferation
US8420388B2 (en) 2008-06-30 2013-04-16 Cho-A Pharm. Co., Ltd. Gene of porcine beta casein, a promoter of the same and the use thereof
EP2305814B1 (en) 2008-06-30 2015-08-05 Cho-A Pharm Co., Ltd. Gene of porcine alpha-s1 casein, a promoter of the same and use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005796A1 (en) * 1992-09-10 1994-03-17 American Red Cross Long wap promoter for mammary expression of human protein c
US5955422A (en) * 1983-12-13 1999-09-21 Kirin-Amgen, Inc. Production of erthropoietin
US5959171A (en) * 1994-08-17 1999-09-28 Pharming B.V. Method for the production of biologically active polypeptides in a mammal's

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955422A (en) * 1983-12-13 1999-09-21 Kirin-Amgen, Inc. Production of erthropoietin
WO1994005796A1 (en) * 1992-09-10 1994-03-17 American Red Cross Long wap promoter for mammary expression of human protein c
US5959171A (en) * 1994-08-17 1999-09-28 Pharming B.V. Method for the production of biologically active polypeptides in a mammal's

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
Biol. Res., Vol.28, 1995, pp.141-153 *
Blood, Vol.85, 1995, pp.2735-2741 *
DNA Cell Biol., Vol.18, 1999, p.845 *
Eur. J. Biochem., Vol.245, 1997, pp.482-489 *
Mol. Biol. Res., Vol.5, 1989, pp.255-261 *
P.N.A.S., Vol.87, 1990, pp.5178-5182 *
Transgenic Res., Vol.6, 1997, pp.75-84 *
Transgenic Res., Vol.7, 1998, pp.311-317 *

Also Published As

Publication number Publication date
KR20010081456A (en) 2001-08-29
KR100358754B1 (en) 2002-11-07
AU2000255759A1 (en) 2001-08-20
WO2001059074A1 (en) 2001-08-16
GB2376024A (en) 2002-12-04
GB0220971D0 (en) 2002-10-23

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20180628