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GB2101070A - Deformable container for liquid pharmaceuticals - Google Patents

Deformable container for liquid pharmaceuticals Download PDF

Info

Publication number
GB2101070A
GB2101070A GB08216489A GB8216489A GB2101070A GB 2101070 A GB2101070 A GB 2101070A GB 08216489 A GB08216489 A GB 08216489A GB 8216489 A GB8216489 A GB 8216489A GB 2101070 A GB2101070 A GB 2101070A
Authority
GB
United Kingdom
Prior art keywords
container
outlet
throttle
liquid
breaking point
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08216489A
Inventor
Rainer Conrad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rowenta Werke GmbH
Original Assignee
Rowenta Werke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rowenta Werke GmbH filed Critical Rowenta Werke GmbH
Publication of GB2101070A publication Critical patent/GB2101070A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/067Flexible ampoules, the contents of which are expelled by squeezing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Closures For Containers (AREA)
  • Tubes (AREA)

Abstract

A container 1 for liquid pharmaceuticals particular for use in an ultrasonic inhaler comprises a deformable bellows 3 and a tubular outlet 2. A throttle 4 is provided in the outlet, which also has a pre-set breaking point 5. A pin 7 formed on the base wall 6 ruptures the top wall 8 on deformation of the container to prevent re-use. <IMAGE>

Description

SPECIFICATION Container for liquid pharmaceuticals This invention relates to a container with deformable walls and an outlet for liquid pharmaceuticals particularly for inhalants and for use in ultrasonic inhalers or similar pressuretype metering devices.
it is known to pack liquid pharmaceuticals, such as, for example, liquid inhalers, in dosage-unit packages and supply then in this form. The packages are opened at the place of use and the active substance contained therein is then administered. A disadvantage of the known packages is that it is impossible to empty them totally of their contents, even if the package has elastically deformable walls.
A certain residual amount is always left in the package. Not only is this very costly since the pharmaceutical contained in the container is sometimes extremely expensive, but also it is not entirely safe if residual amounts are left in the container, as these residues often have highly toxic properties.
According to the invention there is provided a container for liquid pharmaceuticals and for use in ultrasonic inhalers or similar pressuretype metering devices, in which the wall or walls of the container is/are constructed as a deformable concertina-like bellows and including a tubular outlet in which is provided a throttle, said outlet has a preset breaking point such a container does not have the disadvantages mentioned above and the contents can readily be conveyed through an outlet to the place of use, in a pressure-type metering device.
This makes it possible to empty out all the liquid pharmaceutical product contained in the container in a pressure-type metering device.
The piston or plunger of the metering device presses against the base of the container in such a way that the wall collapses, under the effect of the bellows. The throttle provided in the tubular outlet and either made of a feltlike material acting as a wick or made of ceramic material or the like prevents the liquid contained in the package from flowing out when the pressure-type metering device is not in operation.
The pharmaceutical liquid may be sealed in the container during transportation, and at the place of use the outlet is snapped off at the breaking point provided and in this way the outlet is opened. Preferably, the outlet and throttle are heat-resistant up to + 90"C. The advantageous choice of a material which is heat-resistant up to + 90"C for both the outlet and the choke also makes it possible to heat the contents of the container before use, e.g. by placing the outlet in an electrically heated channel.
It is additionally particularly advantageous to have a pin formed or injection-moulded on the inside of the base of the container. This ensures that, once the container has been emptied, the pin permanently damages the wall of the container so that it cannot be reused and possibly refilled with the wrong, possible highly toxic inhalants by a layman.
According to a further preferred feature of the invention, half a press-stud may be formed on the inside of the base of the container whilst the matching other half of the press-stud is fixed to the inside of the opposite end of the container. This means that, when the container is totally empty, the two halves of the press-stud on the two inner surfaces of the container engage with each other and thus make it impossible to refill the container. The two end surface are held together by the press-stud and the bellows of the container cannot move back.
An embodiment by way of example of the invention is shown in the Figure and described more fully hereinafter.The container according to the invention consists of the actual container 1 with deformable walls and the outlet 2. The walls of the container 1 are constructed in the form of a concertina-bellows 3. The outlet 2 has a pre-set breaking point 5. Between the breaking point 5 and the container 1, a throttle 4 is inserted in the upper portion of the outlet 2. The throttle 4 may consist of natural or artificial fibers. However, it is also possible to use a mineral raw material for the throttle 4. A pin 7 is formed on the container base 6 inside the container 1. When the container 1 according to the invention is used, first the outlet 2 is broken off or severed at the breaking point 5.It is possible to have a blade provided in the administration apparatus to open the outlet 2 at the breaking point 5. As a result of the compression of the container 1 from the container base 6 upwards, the contents of the container 1 are delivered to the place of use.
The bellows 3 are compressed. As the container 1 is totally emptied, the pin 7 is pushed against the end 8 of the container and penetrates this end 8. This permanently damages the end 8 of the container so that the container according to the invention cannot be reused.
1. A container for liquid pharmaceuticals and for use in ultrasonic inhalers or similar pressure-type metering devices, in which the wall or of the container is/are constructed as a deformable concertina-like bellows and including a tubular outlet in which is provided said outlet has a preset breaking point.
2. A container according to claim 1, in which the outlet and the throttle are heatresistant up to + 90"C.
3. A container according to claim 1 or 2 in which a pin is formed or injection-moulded on the inside of the base of the container.
**WARNING** end of DESC field may overlap start of CLMS **.

Claims (5)

**WARNING** start of CLMS field may overlap end of DESC **. SPECIFICATION Container for liquid pharmaceuticals This invention relates to a container with deformable walls and an outlet for liquid pharmaceuticals particularly for inhalants and for use in ultrasonic inhalers or similar pressuretype metering devices. it is known to pack liquid pharmaceuticals, such as, for example, liquid inhalers, in dosage-unit packages and supply then in this form. The packages are opened at the place of use and the active substance contained therein is then administered. A disadvantage of the known packages is that it is impossible to empty them totally of their contents, even if the package has elastically deformable walls. A certain residual amount is always left in the package. Not only is this very costly since the pharmaceutical contained in the container is sometimes extremely expensive, but also it is not entirely safe if residual amounts are left in the container, as these residues often have highly toxic properties. According to the invention there is provided a container for liquid pharmaceuticals and for use in ultrasonic inhalers or similar pressuretype metering devices, in which the wall or walls of the container is/are constructed as a deformable concertina-like bellows and including a tubular outlet in which is provided a throttle, said outlet has a preset breaking point such a container does not have the disadvantages mentioned above and the contents can readily be conveyed through an outlet to the place of use, in a pressure-type metering device. This makes it possible to empty out all the liquid pharmaceutical product contained in the container in a pressure-type metering device. The piston or plunger of the metering device presses against the base of the container in such a way that the wall collapses, under the effect of the bellows. The throttle provided in the tubular outlet and either made of a feltlike material acting as a wick or made of ceramic material or the like prevents the liquid contained in the package from flowing out when the pressure-type metering device is not in operation. The pharmaceutical liquid may be sealed in the container during transportation, and at the place of use the outlet is snapped off at the breaking point provided and in this way the outlet is opened. Preferably, the outlet and throttle are heat-resistant up to + 90"C. The advantageous choice of a material which is heat-resistant up to + 90"C for both the outlet and the choke also makes it possible to heat the contents of the container before use, e.g. by placing the outlet in an electrically heated channel. It is additionally particularly advantageous to have a pin formed or injection-moulded on the inside of the base of the container. This ensures that, once the container has been emptied, the pin permanently damages the wall of the container so that it cannot be reused and possibly refilled with the wrong, possible highly toxic inhalants by a layman. According to a further preferred feature of the invention, half a press-stud may be formed on the inside of the base of the container whilst the matching other half of the press-stud is fixed to the inside of the opposite end of the container. This means that, when the container is totally empty, the two halves of the press-stud on the two inner surfaces of the container engage with each other and thus make it impossible to refill the container. The two end surface are held together by the press-stud and the bellows of the container cannot move back. An embodiment by way of example of the invention is shown in the Figure and described more fully hereinafter.The container according to the invention consists of the actual container 1 with deformable walls and the outlet 2. The walls of the container 1 are constructed in the form of a concertina-bellows 3. The outlet 2 has a pre-set breaking point 5. Between the breaking point 5 and the container 1, a throttle 4 is inserted in the upper portion of the outlet 2. The throttle 4 may consist of natural or artificial fibers. However, it is also possible to use a mineral raw material for the throttle 4. A pin 7 is formed on the container base 6 inside the container 1. When the container 1 according to the invention is used, first the outlet 2 is broken off or severed at the breaking point 5.It is possible to have a blade provided in the administration apparatus to open the outlet 2 at the breaking point 5. As a result of the compression of the container 1 from the container base 6 upwards, the contents of the container 1 are delivered to the place of use. The bellows 3 are compressed. As the container 1 is totally emptied, the pin 7 is pushed against the end 8 of the container and penetrates this end 8. This permanently damages the end 8 of the container so that the container according to the invention cannot be reused. CLAIMS
1. A container for liquid pharmaceuticals and for use in ultrasonic inhalers or similar pressure-type metering devices, in which the wall or of the container is/are constructed as a deformable concertina-like bellows and including a tubular outlet in which is provided said outlet has a preset breaking point.
2. A container according to claim 1, in which the outlet and the throttle are heatresistant up to + 90"C.
3. A container according to claim 1 or 2 in which a pin is formed or injection-moulded on the inside of the base of the container.
4. A container according to any of the preceding claims, in which half a press-stud is formed or injection-moulded on the inside of the base of the container and the cooperating other half of the press-stud is fixed to the inside of the opposite end of the container.
5. A container for liquid pharmaceuticals substantially as herein described with reference to the accompanying drawings.
GB08216489A 1981-06-06 1982-06-07 Deformable container for liquid pharmaceuticals Withdrawn GB2101070A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3122680 1981-06-06

Publications (1)

Publication Number Publication Date
GB2101070A true GB2101070A (en) 1983-01-12

Family

ID=6134182

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08216489A Withdrawn GB2101070A (en) 1981-06-06 1982-06-07 Deformable container for liquid pharmaceuticals

Country Status (4)

Country Link
JP (1) JPS5836561A (en)
FR (1) FR2507085A1 (en)
GB (1) GB2101070A (en)
NL (1) NL8202261A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006067490A3 (en) * 2004-12-23 2006-10-05 Kathleen Amanda Thomson A pack

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0236518Y2 (en) * 1986-05-07 1990-10-04

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006067490A3 (en) * 2004-12-23 2006-10-05 Kathleen Amanda Thomson A pack

Also Published As

Publication number Publication date
JPS5836561A (en) 1983-03-03
FR2507085A1 (en) 1982-12-10
NL8202261A (en) 1983-01-03

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)