GB2034695B - Acylation of 6-apa via silyl intermediates - Google Patents
Acylation of 6-apa via silyl intermediatesInfo
- Publication number
- GB2034695B GB2034695B GB7933614A GB7933614A GB2034695B GB 2034695 B GB2034695 B GB 2034695B GB 7933614 A GB7933614 A GB 7933614A GB 7933614 A GB7933614 A GB 7933614A GB 2034695 B GB2034695 B GB 2034695B
- Authority
- GB
- United Kingdom
- Prior art keywords
- apa
- acylation
- intermediates
- via silyl
- silyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 title 1
- 230000010933 acylation Effects 0.000 title 1
- 238000005917 acylation reaction Methods 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7933614A GB2034695B (en) | 1978-10-06 | 1979-09-27 | Acylation of 6-apa via silyl intermediates |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7839599 | 1978-10-06 | ||
| GB7933614A GB2034695B (en) | 1978-10-06 | 1979-09-27 | Acylation of 6-apa via silyl intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2034695A GB2034695A (en) | 1980-06-11 |
| GB2034695B true GB2034695B (en) | 1982-10-27 |
Family
ID=26269104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7933614A Expired GB2034695B (en) | 1978-10-06 | 1979-09-27 | Acylation of 6-apa via silyl intermediates |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2034695B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2125807B (en) * | 1982-05-26 | 1986-01-08 | Lilly Industries Ltd | Preparation of penicillin and cephalosporin compounds and novel intermediates useful therein |
| HU221200B1 (en) * | 1990-01-22 | 2002-08-28 | Biochemie Gmbh | Process for producing beta-lactames |
| EP0953569A1 (en) * | 1998-04-29 | 1999-11-03 | Gist-Brocades B.V. | Preparation of beta-lactam antibiotics in the presence of urea or amide |
| CN111205305B (en) * | 2020-02-07 | 2021-10-22 | 山东二叶制药有限公司 | The preparation technology of cloxacillin sodium |
-
1979
- 1979-09-27 GB GB7933614A patent/GB2034695B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2034695A (en) | 1980-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |