GB202114105D0 - Nucleotide synthesis - Google Patents
Nucleotide synthesisInfo
- Publication number
- GB202114105D0 GB202114105D0 GBGB2114105.6A GB202114105A GB202114105D0 GB 202114105 D0 GB202114105 D0 GB 202114105D0 GB 202114105 A GB202114105 A GB 202114105A GB 202114105 D0 GB202114105 D0 GB 202114105D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- nucleotide synthesis
- nucleotide
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 239000002773 nucleotide Substances 0.000 title 1
- 125000003729 nucleotide group Chemical group 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2114105.6A GB202114105D0 (en) | 2021-10-01 | 2021-10-01 | Nucleotide synthesis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB2114105.6A GB202114105D0 (en) | 2021-10-01 | 2021-10-01 | Nucleotide synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB202114105D0 true GB202114105D0 (en) | 2021-11-17 |
Family
ID=78497817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB2114105.6A Ceased GB202114105D0 (en) | 2021-10-01 | 2021-10-01 | Nucleotide synthesis |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB202114105D0 (en) |
Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005797A1 (en) | 1992-09-01 | 1994-03-17 | Vsevolod Kiselev | Synthesis of dna molecules in vitro |
| US5714320A (en) | 1993-04-15 | 1998-02-03 | University Of Rochester | Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides |
| EP0823479A2 (en) | 1996-08-06 | 1998-02-11 | F. Hoffmann-La Roche Ag | Modified thermostable DNA polymerase |
| WO2000015779A2 (en) | 1998-09-15 | 2000-03-23 | Yale University | Molecular cloning using rolling circle amplification |
| WO2002057487A2 (en) | 2001-01-19 | 2002-07-25 | Amersham Biosciences Uk Limited | Suppression of non-specific nucleic acid amplification |
| WO2004057010A2 (en) | 2002-12-23 | 2004-07-08 | Scinopharm Singapore Pte Ltd | Deoxyribonucleotides manufacturing by enzymatic reduction of ribonucleotides |
| WO2005030983A2 (en) | 2003-09-26 | 2005-04-07 | Circleamp, Inc. | Amplification of polynucleotides by rolling circle amplification |
| WO2006119066A2 (en) | 2005-04-29 | 2006-11-09 | The J. Craig Venter Institute | Amplification and cloning of single dna molecules using rolling circle amplification |
| WO2010086626A1 (en) | 2009-01-30 | 2010-08-05 | Touchlight Genetics Limited | Production of closed linear dna |
| WO2011123021A1 (en) | 2010-03-31 | 2011-10-06 | Fredrik Tholander | Method for determining the amount of dntp |
| WO2012017210A1 (en) | 2010-08-04 | 2012-02-09 | Touchlight Genetics Limited | Production of closed linear dna using a palindromic sequence |
| WO2014018675A1 (en) | 2012-07-24 | 2014-01-30 | President And Fellows Of Harvard College | Self-assembly of nucleic acid nanostructures |
| WO2014135859A1 (en) | 2013-03-05 | 2014-09-12 | Touchlight Genetics Limited | Synthesis apparatus and method |
| WO2015079042A1 (en) | 2013-11-29 | 2015-06-04 | Q-Linea Ab | Rolling circle amplification method |
| US9125845B2 (en) | 2008-07-09 | 2015-09-08 | General Electric Company | DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same |
| WO2016034849A1 (en) | 2014-09-05 | 2016-03-10 | Touchlight Genetics Limited | Synthesis of dna |
| WO2016132129A1 (en) | 2015-02-17 | 2016-08-25 | Touchlight Genetics Limited | Method of dna synthesis |
| WO2019075167A1 (en) | 2017-10-11 | 2019-04-18 | Greenlight Biosciences, Inc. | Methods and compositions for nucleoside triphosphate and ribonucleic acid production |
| WO2021156619A1 (en) | 2020-02-04 | 2021-08-12 | FabricNano Limited | Nucleic acid nanostructures |
-
2021
- 2021-10-01 GB GBGB2114105.6A patent/GB202114105D0/en not_active Ceased
Patent Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005797A1 (en) | 1992-09-01 | 1994-03-17 | Vsevolod Kiselev | Synthesis of dna molecules in vitro |
| US5714320A (en) | 1993-04-15 | 1998-02-03 | University Of Rochester | Rolling circle synthesis of oligonucleotides and amplification of select randomized circular oligonucleotides |
| EP0823479A2 (en) | 1996-08-06 | 1998-02-11 | F. Hoffmann-La Roche Ag | Modified thermostable DNA polymerase |
| WO2000015779A2 (en) | 1998-09-15 | 2000-03-23 | Yale University | Molecular cloning using rolling circle amplification |
| WO2002057487A2 (en) | 2001-01-19 | 2002-07-25 | Amersham Biosciences Uk Limited | Suppression of non-specific nucleic acid amplification |
| WO2004057010A2 (en) | 2002-12-23 | 2004-07-08 | Scinopharm Singapore Pte Ltd | Deoxyribonucleotides manufacturing by enzymatic reduction of ribonucleotides |
| WO2005030983A2 (en) | 2003-09-26 | 2005-04-07 | Circleamp, Inc. | Amplification of polynucleotides by rolling circle amplification |
| WO2006119066A2 (en) | 2005-04-29 | 2006-11-09 | The J. Craig Venter Institute | Amplification and cloning of single dna molecules using rolling circle amplification |
| US9125845B2 (en) | 2008-07-09 | 2015-09-08 | General Electric Company | DNA vaccines, uses for unprocessed rolling circle amplification product and methods for making the same |
| WO2010086626A1 (en) | 2009-01-30 | 2010-08-05 | Touchlight Genetics Limited | Production of closed linear dna |
| WO2011123021A1 (en) | 2010-03-31 | 2011-10-06 | Fredrik Tholander | Method for determining the amount of dntp |
| WO2012017210A1 (en) | 2010-08-04 | 2012-02-09 | Touchlight Genetics Limited | Production of closed linear dna using a palindromic sequence |
| WO2014018675A1 (en) | 2012-07-24 | 2014-01-30 | President And Fellows Of Harvard College | Self-assembly of nucleic acid nanostructures |
| WO2014135859A1 (en) | 2013-03-05 | 2014-09-12 | Touchlight Genetics Limited | Synthesis apparatus and method |
| WO2015079042A1 (en) | 2013-11-29 | 2015-06-04 | Q-Linea Ab | Rolling circle amplification method |
| WO2016034849A1 (en) | 2014-09-05 | 2016-03-10 | Touchlight Genetics Limited | Synthesis of dna |
| WO2016132129A1 (en) | 2015-02-17 | 2016-08-25 | Touchlight Genetics Limited | Method of dna synthesis |
| WO2019075167A1 (en) | 2017-10-11 | 2019-04-18 | Greenlight Biosciences, Inc. | Methods and compositions for nucleoside triphosphate and ribonucleic acid production |
| WO2021156619A1 (en) | 2020-02-04 | 2021-08-12 | FabricNano Limited | Nucleic acid nanostructures |
Non-Patent Citations (52)
| Title |
|---|
| ACS CHEM. BIOL., vol. 11, no. 12, 2016, pages 3289 - 3293 |
| APP. BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 190, no. 4, 2020, pages 1271 - 1288 |
| BAO, J.RYU, D. D.: "Total biosynthesis of deoxynucleoside triphosphates using deoxynucleoside monophosphate kinases for PCR application", BIOTECHNOLOGY AND BIOENGINEERING, vol. 98, no. 1, 2007, pages 1 - 11, XP071113807, DOI: 10.1002/bit.21498 |
| BARNES, GENE, vol. 112, 1992, pages 29 - 35 |
| BIOTECHNIQUES, vol. 54, June 2013 (2013-06-01), pages 337 - 343 |
| BURKE ET AL.: "DNA synthesis from diphosphate substrates by DNA polymerases", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 115, no. 5, 2018, pages 980 - 985, XP055768590, DOI: 10.1073/pnas.1712193115 |
| BURKELUPTAK, PNAS, vol. 115, no. 5, 30 January 2018 (2018-01-30), pages 980 - 985 |
| CAS , no. 9025-82-5 |
| CHAMBERS, R. W.KHORANA, H. G.: "Nucleoside Polyphosphates. V. 1 Syntheses of Guanosine 5'-Di-and Triphosphates", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 79, no. 14, 1957, pages 3752 - 3755, XP002222553, DOI: 10.1021/ja01571a037 |
| CRANS, D. C.WHITESIDES, G. M.: "A convenient synthesis of disodium acetyl phosphate for use in in situ ATP cofactor regeneration", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 48, no. 18, 1983, pages 3130 - 3132 |
| DUCANI ET AL., NATURE METHODS, 2013 |
| DUCANI ET AL., NATURE METHODS, vol. 10, no. 7, 2013, pages 647 |
| ESTEBAN ET AL., J BIOL CHEM., vol. 268, no. 4, 5 February 1993 (1993-02-05), pages 2719 - 26 |
| FAIRMAN, J. W.WIJERATHNA, S. R.AHMAD, M. F.XU, H.NAKANO, R.JHA, S.NORDLUND, P.: "Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization", NATURE STRUCTURAL & MOLECULAR BIOLOGY, vol. 18, no. 3, 2011, pages 316 |
| FU ET AL., J. AM. CHEM. SOC., vol. 134, no. 12, 2012, pages 5516 - 5519 |
| FU, INTERENZYME SUBSTRATE DIFFUSION FOR AN ENZYME CASCADE ORGANIZED ON SPATIALLY ADDRESSABLE DNA NANOSTRUCTURES, 2012 |
| FUJIMOTO, M.KUNINAKA, A.YOSHINO, H., AGRIC. BIOL. CHEM., vol. 38, 1974, pages 777 - 783 |
| GENOME RES, vol. 11, 2001, pages 1095 - 1099 |
| GERRARD ET AL., ACS NANO, vol. 6, no. 10, 2012, pages 9221 - 9228 |
| GILLGHAEMI, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, vol. 27, 2008, pages 224 - 243 |
| HAFNER ET AL., BIOTECHNIQUES, vol. 30, April 2001 (2001-04-01), pages 852 - 867 |
| HAMADA, SCIENCE ROBOTICS, vol. 4, 10 April 2019 (2019-04-10) |
| HUANG, Z. ET AL., BIOTECHNIQUES, vol. 20, 1996, pages 1012 - 1020 |
| JONEJA, A.HUANG, X.: "Linear nicking endonuclease-mediated strand-displacement DNA amplification", ANALYTICAL BIOCHEMISTRY, vol. 414, no. 1, 2011, pages 58 - 69, XP028384447, DOI: 10.1016/j.ab.2011.02.025 |
| JONEJAHUANG, ANALYTICAL CHEMISTRY, vol. 414, 2011, pages 48 - 69 |
| JONG ET AL., JOURNAL OF BIOMEDICAL SCIENCE, vol. 5, 1998, pages 62 - 68 |
| KEARNEY ET AL.: "DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior", ADVANCED MATERIALS, vol. 28, no. 27, February 2016 (2016-02-01) |
| KNIERIM, E.LUCKE, B.SCHWARZ, J. M.SCHUELKE, M.SEELOW, D.: "Systematic comparison of three methods for fragmentation of long-range PCR products for next generation sequencing", PLOS ONE, vol. 6, no. 11, 2011, pages e28240, XP055236211, DOI: 10.1371/journal.pone.0028240 |
| KUMARCHERNAYA, BIOTECHNIQUES, vol. 47, July 2009 (2009-07-01), pages 637 - 639 |
| KUNKEL, T.A.TINDALL, K.R., BIOCHEMISTRY, vol. 27, 1988, pages 6008 - 6013 |
| LADNER, W. E.WHITESIDES, G. M.: "Enzymic synthesis of deoxyATP using DNA as starting material", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 50, no. 7, 1985, pages 1076 - 1079 |
| LENGSFELD, C. S.ANCHORDOQUY, T. J.: "Shear-induced degradation of plasmid DNA", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 91, no. 7, 2002, pages 1581 - 1589 |
| LI, L.JIN, M.SUN, C.WANG, X.XIE, S.ZHOU, G.SHUI, L.: "High efficiency hydrodynamic DNA fragmentation in a bubbling system", SCIENTIFIC REPORTS, vol. 7, no. 1, 2017, pages 1 - 9 |
| LITTLE, J.W., GENE AMPLIF. ANAL., vol. 2, 1981, pages 135 - 145 |
| LIU, A THREE-ENZYME PATHWAY WITH AN OPTIMISED GEOMETRIC ARRANGEMENT TO FACILITATE SUBSTRATE TRANSFER, 2016 |
| LOAN ET AL., SCIENTIFIC REPORTS, vol. 9, 2019, pages 2019 |
| LOWENTHAL, M. S.QUITTMAN, E.PHINNEY, K. W.: "Absolute quantification of RNA or DNA using acid hydrolysis and mass spectrometry", ANALYTICAL CHEMISTRY, vol. 91, no. 22, 2019, pages 14569 - 14576 |
| MARTH, PRECISION TEMPLATED BOTTOM-UP MULTIPROTEIN NANOASSEMBLY THROUGH DEFINED CLICK CHEMISTRY LINKAGE TO DNA, 2017 |
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| PARK ET AL., THE JOURNAL OF MOLECULAR DIAGNOSTICS, 2020, Retrieved from the Internet <URL:https://doi.ora/10.1016/i.imoldx.2020.03.006> |
| ROSIER, A DNA-BASED SYNTHETIC APOPTOSOME, 2019 |
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| WANG ET AL.: "Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, no. 34, 2012, pages 28215 - 28226 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |