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GB201411241D0 - Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders - Google Patents

Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Info

Publication number
GB201411241D0
GB201411241D0 GBGB1411241.1A GB201411241A GB201411241D0 GB 201411241 D0 GB201411241 D0 GB 201411241D0 GB 201411241 A GB201411241 A GB 201411241A GB 201411241 D0 GB201411241 D0 GB 201411241D0
Authority
GB
United Kingdom
Prior art keywords
dihydropyridoisoquinolinones
novel
treatment
pharmaceutical compositions
inflammatory disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1411241.1A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galapagos NV
Original Assignee
Galapagos NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galapagos NV filed Critical Galapagos NV
Priority to GBGB1411241.1A priority Critical patent/GB201411241D0/en
Publication of GB201411241D0 publication Critical patent/GB201411241D0/en
Priority to PCT/EP2015/063965 priority patent/WO2015197550A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1411241.1A 2014-06-25 2014-06-25 Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders Ceased GB201411241D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1411241.1A GB201411241D0 (en) 2014-06-25 2014-06-25 Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders
PCT/EP2015/063965 WO2015197550A1 (en) 2014-06-25 2015-06-22 Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1411241.1A GB201411241D0 (en) 2014-06-25 2014-06-25 Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
GB201411241D0 true GB201411241D0 (en) 2014-08-06

Family

ID=51410058

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1411241.1A Ceased GB201411241D0 (en) 2014-06-25 2014-06-25 Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders

Country Status (2)

Country Link
GB (1) GB201411241D0 (en)
WO (1) WO2015197550A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201506894D0 (en) * 2015-04-23 2015-06-10 Galapagos Nv Novel dihydropyridoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders
JP6918957B2 (en) * 2017-03-06 2021-08-11 上海 インスティテュート オブ マテリア メディカ、チャイニーズ アカデミー オブ サイエンシーズＳｈａｎｇｈａｉ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｍａｔｅｒｉａ Ｍｅｄｉｃａ， Ｃｈｉｎｅｓｅ Ａｃａｄｅｍｙ Ｏｆ Ｓｃｉｅｎｃｅｓ GPR84 receptor antagonist and its use
EP3403649A1 (en) 2017-05-16 2018-11-21 Bayer Pharma Aktiengesellschaft Inhibitors and antagonists of gpr84 for the treatment of endometriosis
JP2021502987A (en) 2017-11-15 2021-02-04 ガラパゴス・ナムローゼ・フェンノートシャップＧａｌａｐａｇｏｓ Ｎ．Ｖ． Compounds and pharmaceutical compositions thereof for use in the treatment of fibrotic diseases
US20230112499A1 (en) 2019-12-19 2023-04-13 Bayer Aktiengesellschaft Furoindazole derivatives
MX2023009059A (en) 2021-02-02 2023-09-15 Liminal Biosciences Ltd GPR84 ANTAGONISTS AND USES OF THESE.
CA3211437A1 (en) 2021-02-23 2022-09-01 Bayer Aktiengesellschaft Furoindazole derivatives as gpr84 antagonists
WO2022194267A1 (en) * 2021-03-18 2022-09-22 武汉人福创新药物研发中心有限公司 Gpr84 antagonist, and preparation method therefor and use thereof
WO2022218372A1 (en) * 2021-04-14 2022-10-20 武汉人福创新药物研发中心有限公司 Dihydropyrimidoisoquinolinone derivative and use thereof
WO2022229061A1 (en) 2021-04-29 2022-11-03 Bayer Aktiengesellschaft Furoindazole derivatives as antagonists or inhibitors of gpr84
US20240287064A1 (en) * 2021-06-21 2024-08-29 Wuhan Humanwell Innovative Drug Research and Development Center Limited Company Tricyclic compound used as gpr84 antagonist
CN115611944A (en) 2021-07-15 2023-01-17 中国科学院上海药物研究所 Asymmetric GPR84 antagonists and uses thereof
WO2024083705A1 (en) 2022-10-18 2024-04-25 Bayer Aktiengesellschaft Furoindazole derivatives for the treatment of pain

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR089284A1 (en) * 2011-12-22 2014-08-13 Galapagos Nv DIHYDROPIRIMIDINOISOQUINOLINONES AND PHARMACEUTICAL COMPOSITIONS OF THE SAME FOR THE TREATMENT OF INFLAMMATORY DISORDERS

Also Published As

Publication number Publication date
WO2015197550A1 (en) 2015-12-30

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)