GB201210328D0 - Biomarker - Google Patents
BiomarkerInfo
- Publication number
- GB201210328D0 GB201210328D0 GB201210328A GB201210328A GB201210328D0 GB 201210328 D0 GB201210328 D0 GB 201210328D0 GB 201210328 A GB201210328 A GB 201210328A GB 201210328 A GB201210328 A GB 201210328A GB 201210328 D0 GB201210328 D0 GB 201210328D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- patient
- methods
- relates
- tnf
- symptoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000000090 biomarker Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 201000006417 multiple sclerosis Diseases 0.000 abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010054094 Tumour necrosis Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention relates to methods of determining whether or not a patient is suitable for anti-tumour necrosis factor (anti-TNF) therapy. The invention also relates to methods of treating autoimmune diseases and methods of identifying whether or not a patient is at risk of developing multiple sclerosis (MS) or MS-like symptoms or whether or not a patient has MS. The invention further provides novel polypeptide TNF antagonists and related polynucleotides, expression vectors, host cells and antibodies.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201210328A GB201210328D0 (en) | 2012-06-12 | 2012-06-12 | Biomarker |
| PCT/GB2013/051518 WO2013186541A1 (en) | 2012-06-12 | 2013-06-10 | Biomarker for determining the suitability of anti -tumour necrosis factor (anti-tnf) therapy in the treatment of autoimmune diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201210328A GB201210328D0 (en) | 2012-06-12 | 2012-06-12 | Biomarker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201210328D0 true GB201210328D0 (en) | 2012-07-25 |
Family
ID=46605772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB201210328A Ceased GB201210328D0 (en) | 2012-06-12 | 2012-06-12 | Biomarker |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB201210328D0 (en) |
| WO (1) | WO2013186541A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7939634B2 (en) * | 2004-01-27 | 2011-05-10 | Compugen Ltd. | Polynucleotides encoding polypeptides and methods using same |
| US7785834B2 (en) * | 2005-11-10 | 2010-08-31 | Ercole Biotech, Inc. | Soluble TNF receptors and their use in treatment of disease |
| EP2069533B1 (en) * | 2006-07-13 | 2012-11-07 | Life Technologies Corporation | Gene expression profiling for identification, monitoring and treatment of multiple sclerosis |
| WO2008093323A2 (en) * | 2007-01-29 | 2008-08-07 | Compugen Ltd. | Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis |
-
2012
- 2012-06-12 GB GB201210328A patent/GB201210328D0/en not_active Ceased
-
2013
- 2013-06-10 WO PCT/GB2013/051518 patent/WO2013186541A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013186541A1 (en) | 2013-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |