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GB201112607D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
GB201112607D0
GB201112607D0 GBGB1112607.5A GB201112607A GB201112607D0 GB 201112607 D0 GB201112607 D0 GB 201112607D0 GB 201112607 A GB201112607 A GB 201112607A GB 201112607 D0 GB201112607 D0 GB 201112607D0
Authority
GB
United Kingdom
Prior art keywords
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1112607.5A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GBGB1112607.5A priority Critical patent/GB201112607D0/en
Publication of GB201112607D0 publication Critical patent/GB201112607D0/en
Priority to PCT/EP2011/068085 priority patent/WO2012052390A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB1112607.5A 2010-10-19 2011-07-22 Novel compounds Ceased GB201112607D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1112607.5A GB201112607D0 (en) 2011-07-22 2011-07-22 Novel compounds
PCT/EP2011/068085 WO2012052390A1 (en) 2010-10-19 2011-10-17 N-2-(2-pyridinyl)-4-pyrimidinyl-beta-alanine derivatives as inhibitors of histone demethylase jmjd3

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1112607.5A GB201112607D0 (en) 2011-07-22 2011-07-22 Novel compounds

Publications (1)

Publication Number Publication Date
GB201112607D0 true GB201112607D0 (en) 2011-09-07

Family

ID=44652147

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1112607.5A Ceased GB201112607D0 (en) 2010-10-19 2011-07-22 Novel compounds

Country Status (2)

Country Link
GB (1) GB201112607D0 (en)
WO (1) WO2012052390A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5941546B2 (en) 2011-09-02 2016-06-29 パーデュー、ファーマ、リミテッド、パートナーシップ Pyrimidines as sodium channel blockers
PE20151417A1 (en) * 2012-12-21 2015-10-10 Quanticel Pharmaceuticals Inc HISTONE DESMETILASE INHIBITORS
CN103524535B (en) * 2013-10-16 2016-07-13 苏州云轩医药科技有限公司 There is the Amido thiazole-pyridine heterocycle compound of activity of hedgehog path antagonist
CN103588771B (en) * 2013-01-15 2016-01-27 苏州云轩医药科技有限公司 There is the miazines antineoplastic compound of activity of hedgehog path antagonist
SI2961736T1 (en) * 2013-02-27 2018-06-29 Gilead Sciences, Inc. Inhibitors of histone demethylases
US9133166B2 (en) 2013-03-14 2015-09-15 Quanticel Pharmaceuticals, Inc. Histone demethylase inhibitors
SI2970211T1 (en) * 2013-03-15 2017-12-29 Quanticel Pharmaceuticals Inc. Histone demethylase inhibitors
WO2014190035A2 (en) * 2013-05-21 2014-11-27 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of cancer using histone h3k27me2 biomarkers and modulators
JP6521535B2 (en) 2014-06-25 2019-05-29 セルジーン クオンティセル リサーチ,インク. Histone demethylase inhibitors
US10206930B2 (en) 2015-08-14 2019-02-19 New York University Methods for treating T-cell acute lymphoblastic leukemia
CN106608869B (en) * 2015-10-27 2020-08-04 中国科学院上海药物研究所 Histone demethylase JMJD3 inhibitor and preparation method and application thereof
CN106854181A (en) * 2015-12-08 2017-06-16 湖南华腾制药有限公司 A kind of preparation method of pyrimidine compound
CN120661674A (en) 2016-03-15 2025-09-19 奥莱松基因组股份有限公司 Combination of LSD1 inhibitors for the treatment of solid tumors
WO2018058034A1 (en) 2016-09-23 2018-03-29 Thomas Jefferson University Drug-induced epigenetic remodeling to prevent fibrosis
MA51507A (en) 2016-12-09 2020-11-11 Constellation Pharmaceuticals Inc MARKERS FOR PERSONALIZED CANCER TREATMENT WITH LSD1 INHIBITORS
CN106810538A (en) * 2017-01-09 2017-06-09 湖南华腾制药有限公司 A kind of preparation method of 2 pyrrole radicals pyrimidine derivatives
US20190374525A1 (en) * 2017-02-10 2019-12-12 Temple Otorongo Llc Treatment of diabetes and associated metabolic conditions with epigenetic modulators
US11524011B2 (en) * 2017-09-01 2022-12-13 The Johns Hopkins University H3K27 demethylase inhibitors in pediatric and juvenile osteoporosis
TWI815887B (en) * 2018-05-15 2023-09-21 美商愛彼特生物製藥股份有限公司 Substituted 2,2'-bipyrimidinyl compounds, analogues thereof, and methods using same
CN113387938B (en) * 2020-03-11 2023-08-18 上海科技大学 A kind of substituted pyrimidine compound, its preparation method, intermediate and application
EP4281447A4 (en) * 2021-01-25 2025-06-04 Athos Therapeutics, Inc. Triazine compounds and processes for their preparation and use
CN115466245B (en) * 2022-06-29 2024-04-16 深圳大学 A hydroxamic acid derivative of pyrimidine bipyridine and its preparation method and application

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU570439B2 (en) 1983-03-28 1988-03-17 Compression Labs, Inc. A combined intraframe and interframe transform coding system
US5681835A (en) 1994-04-25 1997-10-28 Glaxo Wellcome Inc. Non-steroidal ligands for the estrogen receptor
GB9716557D0 (en) 1997-08-06 1997-10-08 Glaxo Group Ltd Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity
WO2009087224A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
WO2009114011A1 (en) 2008-03-11 2009-09-17 President And Fellows Of Harvard College Histone demethylation proteins and methods of use thereof
GB0818907D0 (en) * 2008-10-15 2008-11-19 Isis Innovation Histone lysine demethylase inhibitors
LT2349324T (en) 2008-10-17 2017-12-27 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist

Also Published As

Publication number Publication date
WO2012052390A1 (en) 2012-04-26

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)