GB2001963A - Esters of mercaptopropanoic acids - Google Patents
Esters of mercaptopropanoic acidsInfo
- Publication number
- GB2001963A GB2001963A GB7828882A GB7828882A GB2001963A GB 2001963 A GB2001963 A GB 2001963A GB 7828882 A GB7828882 A GB 7828882A GB 7828882 A GB7828882 A GB 7828882A GB 2001963 A GB2001963 A GB 2001963A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lower alkyl
- esters
- mercaptopropanoic
- acids
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PMNLUUOXGOOLSP-UHFFFAOYSA-N 2-mercaptopropanoic acid Chemical class CC(S)C(O)=O PMNLUUOXGOOLSP-UHFFFAOYSA-N 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medical Treatment And Welfare Office Work (AREA)
Abstract
Carboxymethyl esters and salts thereof, have the formula <IMAGE> wherein R is hydrogen or lower alkanoyl; R1 is hydrogen, or lower alkyl; and R2 is hydrogen, lower alkyl, phenyl, phenyl-lower alkyl, 4- hydroxyphenyl-lower alkyl or indolyl- lower alkyl. They may be used as hypotensive agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81547277A | 1977-07-14 | 1977-07-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2001963A true GB2001963A (en) | 1979-02-14 |
| GB2001963B GB2001963B (en) | 1982-02-24 |
Family
ID=25217891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7828882A Expired GB2001963B (en) | 1977-07-14 | 1978-07-05 | Esters of mercaptopropanoic acids |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5419914A (en) |
| AU (1) | AU522452B2 (en) |
| BE (1) | BE869014A (en) |
| CA (1) | CA1090354A (en) |
| CH (1) | CH632490A5 (en) |
| DE (1) | DE2830635A1 (en) |
| DK (1) | DK149770C (en) |
| FR (1) | FR2397401A1 (en) |
| GB (1) | GB2001963B (en) |
| HU (1) | HU177904B (en) |
| IE (1) | IE47423B1 (en) |
| IT (1) | IT1105098B (en) |
| NL (1) | NL7807492A (en) |
| NO (1) | NO146024C (en) |
| SE (1) | SE7807821L (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992000276A3 (en) * | 1990-06-22 | 1992-02-20 | Fisons Plc | Angiotensis converting enzyme inhibitors |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006016517A1 (en) * | 2004-08-13 | 2006-02-16 | Kaneka Corporation | Process for producing optically active 2-substituent-oxy-3-(4-substituent-oxyphenyl)propionic acid derivative |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1527919A (en) * | 1967-03-23 | 1968-06-07 | New derivatives of salicylic acid | |
| BE793887A (en) * | 1972-01-12 | 1973-07-11 | Hoffmann La Roche | ACYLUS DERIVATIVES |
-
1978
- 1978-06-27 CA CA306,339A patent/CA1090354A/en not_active Expired
- 1978-06-28 IE IE1296/78A patent/IE47423B1/en not_active IP Right Cessation
- 1978-06-29 AU AU37588/78A patent/AU522452B2/en not_active Expired
- 1978-07-05 GB GB7828882A patent/GB2001963B/en not_active Expired
- 1978-07-10 IT IT50235/78A patent/IT1105098B/en active
- 1978-07-11 CH CH753578A patent/CH632490A5/en not_active IP Right Cessation
- 1978-07-12 DE DE19782830635 patent/DE2830635A1/en active Granted
- 1978-07-12 HU HU78SU980A patent/HU177904B/en unknown
- 1978-07-12 NL NL7807492A patent/NL7807492A/en not_active Application Discontinuation
- 1978-07-13 DK DK315378A patent/DK149770C/en not_active IP Right Cessation
- 1978-07-13 SE SE7807821A patent/SE7807821L/en unknown
- 1978-07-13 NO NO782429A patent/NO146024C/en unknown
- 1978-07-13 FR FR7821086A patent/FR2397401A1/en active Granted
- 1978-07-14 BE BE189300A patent/BE869014A/en not_active IP Right Cessation
- 1978-07-14 JP JP8668378A patent/JPS5419914A/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992000276A3 (en) * | 1990-06-22 | 1992-02-20 | Fisons Plc | Angiotensis converting enzyme inhibitors |
| US5348978A (en) * | 1990-06-22 | 1994-09-20 | Fisons Plc | Angiotensin converting enzyme inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2001963B (en) | 1982-02-24 |
| DK149770B (en) | 1986-09-29 |
| IT1105098B (en) | 1985-10-28 |
| NO146024B (en) | 1982-04-05 |
| IT7850235A0 (en) | 1978-07-10 |
| AU522452B2 (en) | 1982-06-10 |
| FR2397401A1 (en) | 1979-02-09 |
| FR2397401B1 (en) | 1983-06-17 |
| AU3758878A (en) | 1980-01-03 |
| NO782429L (en) | 1979-01-16 |
| SE7807821L (en) | 1979-01-15 |
| DE2830635C2 (en) | 1988-06-23 |
| BE869014A (en) | 1979-01-15 |
| IE781296L (en) | 1979-01-14 |
| DE2830635A1 (en) | 1979-02-01 |
| CA1090354A (en) | 1980-11-25 |
| NO146024C (en) | 1982-07-14 |
| CH632490A5 (en) | 1982-10-15 |
| NL7807492A (en) | 1979-01-16 |
| DK149770C (en) | 1987-03-09 |
| DK315378A (en) | 1979-01-15 |
| JPS6216943B2 (en) | 1987-04-15 |
| JPS5419914A (en) | 1979-02-15 |
| HU177904B (en) | 1982-01-28 |
| IE47423B1 (en) | 1984-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |