GB2067574B - Microbiologically prepared polypeptide with the amino acid sequence of proinsulin of a primate dna and plasmids which code for this sequence microorganisms which contain this genetic information and processes for their preparation - Google Patents
Microbiologically prepared polypeptide with the amino acid sequence of proinsulin of a primate dna and plasmids which code for this sequence microorganisms which contain this genetic information and processes for their preparationInfo
- Publication number
- GB2067574B GB2067574B GB8101531A GB8101531A GB2067574B GB 2067574 B GB2067574 B GB 2067574B GB 8101531 A GB8101531 A GB 8101531A GB 8101531 A GB8101531 A GB 8101531A GB 2067574 B GB2067574 B GB 2067574B
- Authority
- GB
- United Kingdom
- Prior art keywords
- sequence
- microorganisms
- proinsulin
- preparation
- genetic information
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 241000288906 Primates Species 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title abstract 3
- 239000013612 plasmid Substances 0.000 title abstract 3
- 108010076181 Proinsulin Proteins 0.000 title abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 title abstract 2
- 230000002068 genetic effect Effects 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The process for the preparation of the polypeptide which contains the amino-acid sequence of the proinsulin of primates entails the genetic information for the biosynthesis of the said polypeptide being obtained by means of mRNA from primates, the cDNA being prepared therefrom and inserted into a plasmid, the resulting hybrid plasmid being used to transform microorganisms, and the microorganisms producing the polypeptide being obtained by selection and cultivation.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803001928 DE3001928A1 (en) | 1980-01-19 | 1980-01-19 | GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2067574A GB2067574A (en) | 1981-07-30 |
| GB2067574B true GB2067574B (en) | 1983-10-19 |
Family
ID=6092503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8101531A Expired GB2067574B (en) | 1980-01-19 | 1981-01-19 | Microbiologically prepared polypeptide with the amino acid sequence of proinsulin of a primate dna and plasmids which code for this sequence microorganisms which contain this genetic information and processes for their preparation |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0032675B1 (en) |
| JP (1) | JPS56104897A (en) |
| AT (1) | ATE5151T1 (en) |
| AU (1) | AU545665B2 (en) |
| BE (1) | BE887129A (en) |
| CA (1) | CA1192153A (en) |
| DE (2) | DE3001928A1 (en) |
| ES (3) | ES498451A0 (en) |
| FR (1) | FR2479851A1 (en) |
| GB (1) | GB2067574B (en) |
| IT (1) | IT1136557B (en) |
| NL (1) | NL8100210A (en) |
| SE (1) | SE8100241L (en) |
| ZA (1) | ZA81292B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7066914B2 (en) | 2000-07-12 | 2006-06-27 | Bird Products Corporation | Catheter having a tip with an elongated collar |
| US7976518B2 (en) | 2005-01-13 | 2011-07-12 | Corpak Medsystems, Inc. | Tubing assembly and signal generator placement control device and method for use with catheter guidance systems |
| US9028441B2 (en) | 2011-09-08 | 2015-05-12 | Corpak Medsystems, Inc. | Apparatus and method used with guidance system for feeding and suctioning |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ199391A (en) * | 1981-01-02 | 1985-12-13 | Genentech Inc | Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin |
| ZA824218B (en) * | 1981-06-29 | 1983-04-27 | Cetus Corp | Plasmid for producing human insulin |
| JPS58183659A (en) * | 1982-03-31 | 1983-10-26 | ジェネテイックス、インスチチュ−ト、インコ−ポレ−テッド | Modified proinsulin precursor, dna arrangement for coding same and production thereof |
| EP0098967B1 (en) * | 1982-06-11 | 1989-08-09 | Hoechst Aktiengesellschaft | Process for the preparation of obligate methylotrophic, foreign dna expressing bacteria, and appropriate plasmids and host organisms therefor |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082613A (en) * | 1976-04-23 | 1978-04-04 | The Regents Of The University Of Minnesota | Process for the production of insulin by genetically transformed fungal cells |
| NZ187300A (en) * | 1977-05-27 | 1982-08-17 | Univ California | Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism |
| NL7811041A (en) * | 1977-11-08 | 1979-05-10 | Genentech Inc | IMPROVED METHOD AND MEANS FOR EXPRESSING MICROBIAL POLYPEPTIDE. |
| US4411994A (en) * | 1978-06-08 | 1983-10-25 | The President And Fellows Of Harvard College | Protein synthesis |
| IE48385B1 (en) * | 1978-08-11 | 1984-12-26 | Univ California | Synthesis of a eucaryotic protein by a microorganism |
| GR70279B (en) * | 1979-09-12 | 1982-09-03 | Univ California |
-
1980
- 1980-01-19 DE DE19803001928 patent/DE3001928A1/en not_active Withdrawn
-
1981
- 1981-01-08 AT AT81100069T patent/ATE5151T1/en not_active IP Right Cessation
- 1981-01-08 EP EP81100069A patent/EP0032675B1/en not_active Expired
- 1981-01-08 DE DE8181100069T patent/DE3161251D1/en not_active Expired
- 1981-01-13 ES ES498451A patent/ES498451A0/en active Granted
- 1981-01-16 IT IT8119180A patent/IT1136557B/en active
- 1981-01-16 CA CA000368743A patent/CA1192153A/en not_active Expired
- 1981-01-16 NL NL8100210A patent/NL8100210A/en not_active Application Discontinuation
- 1981-01-16 ZA ZA00810292A patent/ZA81292B/en unknown
- 1981-01-16 SE SE8100241A patent/SE8100241L/en not_active Application Discontinuation
- 1981-01-16 AU AU66280/81A patent/AU545665B2/en not_active Expired
- 1981-01-19 BE BE0/203523A patent/BE887129A/en not_active IP Right Cessation
- 1981-01-19 JP JP524081A patent/JPS56104897A/en active Pending
- 1981-01-19 GB GB8101531A patent/GB2067574B/en not_active Expired
- 1981-01-19 FR FR8100869A patent/FR2479851A1/en not_active Withdrawn
- 1981-02-03 ES ES499053A patent/ES499053A0/en active Granted
- 1981-02-03 ES ES499054A patent/ES499054A0/en active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7066914B2 (en) | 2000-07-12 | 2006-06-27 | Bird Products Corporation | Catheter having a tip with an elongated collar |
| US7976518B2 (en) | 2005-01-13 | 2011-07-12 | Corpak Medsystems, Inc. | Tubing assembly and signal generator placement control device and method for use with catheter guidance systems |
| US9131956B2 (en) | 2005-01-13 | 2015-09-15 | Corpak Medsystems, Inc. | Tubing assembly and signal generator placement control device and method for use with catheter guidance systems |
| US9579488B2 (en) | 2005-01-13 | 2017-02-28 | Corpak Medsystems, Inc. | Tubing assembly and signal generator placement control device and method for use with catheter guidance systems |
| US9028441B2 (en) | 2011-09-08 | 2015-05-12 | Corpak Medsystems, Inc. | Apparatus and method used with guidance system for feeding and suctioning |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2067574A (en) | 1981-07-30 |
| SE8100241L (en) | 1981-07-20 |
| CA1192153A (en) | 1985-08-20 |
| JPS642584A (en) | 1989-01-06 |
| NL8100210A (en) | 1981-08-17 |
| ZA81292B (en) | 1982-02-24 |
| EP0032675A2 (en) | 1981-07-29 |
| FR2479851A1 (en) | 1981-10-09 |
| IT1136557B (en) | 1986-09-03 |
| ES8200722A1 (en) | 1981-11-01 |
| DE3001928A1 (en) | 1981-08-06 |
| ES498451A0 (en) | 1981-11-01 |
| DE3161251D1 (en) | 1984-01-19 |
| JPS56104897A (en) | 1981-08-20 |
| AU545665B2 (en) | 1985-07-25 |
| ES8205427A1 (en) | 1982-06-01 |
| ES8203101A1 (en) | 1982-02-16 |
| AU6628081A (en) | 1981-07-30 |
| ATE5151T1 (en) | 1983-11-15 |
| EP0032675A3 (en) | 1981-11-11 |
| EP0032675B1 (en) | 1983-10-26 |
| ES499053A0 (en) | 1982-02-16 |
| IT8119180A0 (en) | 1981-01-16 |
| ES499054A0 (en) | 1982-06-01 |
| BE887129A (en) | 1981-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2443488A (en) | Dna-molecules coding for fmdh control regions and structured gene for a protein having fmdh-activity and their uses | |
| CZ285453B6 (en) | Dna encoding aspartokinase iii, micro-organism escherichia transformed thereby and process for preparing l-threonine by making use thereof | |
| AU1281495A (en) | Gene coding for adseverins | |
| HUT46061A (en) | Dna sequences encoding hirudin-like protein and process for producing such proteins | |
| HU896613D0 (en) | Process for the preparation of tgf-betal/beta2 chimer | |
| GB2067574B (en) | Microbiologically prepared polypeptide with the amino acid sequence of proinsulin of a primate dna and plasmids which code for this sequence microorganisms which contain this genetic information and processes for their preparation | |
| AU3556784A (en) | A process for preparing vinyl ester resins containing triazine or both triazine and oxazoline groups | |
| AU2795989A (en) | Production of gonorrheal pi proteins and vaccines | |
| EP0139501A3 (en) | The manufacture and expression of genes for thaumatin | |
| EP0002322A3 (en) | Improved triester process for the synthesis of oligonucleotides | |
| ATE89317T1 (en) | PROTEINS, EXPRESSION VECTORS CONTAINING DNA ENCODING FOR SUCH PROTEINS, AND CELLS CONTAINING SUCH EXPRESSION VECTORS. | |
| HUT65492A (en) | Biosynthetic process for the preparation of dedydro-amino acid-remainds and tioether-bridge contaning chemical compounds | |
| EP0063494A3 (en) | Method for producing protein from a microorganism, microorganisms for use in such method and creation thereof, vectors for use in said creation, and protein produced thereby, and transformant culture derived from said microorganisms | |
| EP1123977A4 (en) | GENES ENCODING PROTEINS REGULATING pH OF VACUOLES | |
| EP0644200A4 (en) | Novel cell cortex protein. | |
| AU7880987A (en) | Human B-cell differentiation factor and process of producing said factor | |
| ATE67243T1 (en) | METHOD FOR PRODUCTION OF INSULIN-LIKE GROWTH FACTOR I (IGF-I) AND PLASMID FOR PRODUCTION THEREOF. | |
| KR830005347A (en) | Microbiologically prepared polypeptides having amino acid sequences of proinsulins of primates, DNAs and plasmids coding for microorganisms containing amino acid sequences and genetic information and methods for preparing the same | |
| PT89511A (en) | New growth regulating proteins designated amphiregulin - inhibiting tumours but stimulating some normal cells, also new precursor protein, encoding nucleic acid sequences and antibodies |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |