GB2048250B - 2-amino-6-aryl-4-pyrimidinols and their pharmaceutical uses - Google Patents

2-amino-6-aryl-4-pyrimidinols and their pharmaceutical uses

Info

Publication number: GB2048250B
Authority: GB; United Kingdom
Prior art keywords: pyrimidinols; aryl; amino; pharmaceutical uses; pharmaceutical
Prior art date: 1979-03-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB8008979A

Other versions

GB2048250A (en

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pharmacia and Upjohn Co

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-19

Filing date

1980-03-17

Publication date

1983-04-27

1980-03-17 Application filed by Upjohn Co filed Critical Upjohn Co

1980-12-10 Publication of GB2048250A publication Critical patent/GB2048250A/en

1983-04-27 Application granted granted Critical

1983-04-27 Publication of GB2048250B publication Critical patent/GB2048250B/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

GB8008979A 1979-03-19 1980-03-17 2-amino-6-aryl-4-pyrimidinols and their pharmaceutical uses Expired GB2048250B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2220579A	1979-03-19	1979-03-19
US7985079A	1979-09-28	1979-09-28

Publications (2)

Publication Number	Publication Date
GB2048250A GB2048250A (en)	1980-12-10
GB2048250B true GB2048250B (en)	1983-04-27

Family

ID=26695670

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB8008979A Expired GB2048250B (en)	1979-03-19	1980-03-17	2-amino-6-aryl-4-pyrimidinols and their pharmaceutical uses

Country Status (7)

Country	Link
JP (1)	JPH0627070B2 (en)
CH (1)	CH646958A5 (en)
DE (1)	DE3008693A1 (en)
FR (1)	FR2451918A1 (en)
GB (1)	GB2048250B (en)
IT (1)	IT1143012B (en)
NL (1)	NL8001568A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0111440A1 (en) *	1982-10-15	1984-06-20	Ciba-Geigy Ag	2-Aminopyrimidines, their production and use
US4795812A (en) *	1985-02-05	1989-01-03	The Upjohn Company	4-substituted-6-aryl-pyrimidine compounds
GB9012311D0 (en) *	1990-06-01	1990-07-18	Wellcome Found	Pharmacologically active cns compounds
JP2001505911A (en) *	1996-12-12	2001-05-08	ファルマシア・アンド・アップジョン・カンパニー	How to treat multiple sclerosis
US6495558B1 (en)	1999-01-22	2002-12-17	Amgen Inc.	Kinase inhibitors
EP1144390A2 (en) *	1999-01-22	2001-10-17	Amgen Inc.,	Kinase inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2688019A (en) *	1951-08-25	1954-08-31	Burroughs Wellcome Co	6-aryl-2,4-diamino pyrimidines and process of preparing same
US2723977A (en) *	1953-07-29	1955-11-15	Searle & Co	5, 6-disubstituted 2-amino-4-pyrimidols
US2723978A (en) *	1954-01-14	1955-11-15	Searle & Co	2-amino-5-alkenyl-6-phenyl-4-pyrimidols
US2710867A (en) *	1954-03-12	1955-06-14	Searle & Co	New 2-amino-4-pyrimidol derivatives
US2748121A (en) *	1954-06-17	1956-05-29	Searle & Co	6-nitroaryl derivatives of 2-amino-4-pyrimidols
US2704285A (en) *	1954-06-17	1955-03-15	Searle & Co	2-amino-5-(lower alkyl)-6-substituted phenyl-4-pyrimidols
US3281420A (en) *	1966-01-27	1966-10-25	Searle & Co	Carboxylic acid [2-(2-amino-4-azido-6-phenyl-5-pyrimidinyl)-1-methylethylidene] hydrazides and intermediate
US3412094A (en) *	1967-06-21	1968-11-19	Searle & Co	5-alkyl-2-amino-4-azido-6-phenylpyrimidines and congeners
US3932617A (en) *	1974-05-24	1976-01-13	The Upjohn Company	Interferon induction

1980
- 1980-03-06 DE DE19803008693 patent/DE3008693A1/en active Granted
- 1980-03-10 IT IT48119/80A patent/IT1143012B/en active
- 1980-03-14 CH CH204380A patent/CH646958A5/en not_active IP Right Cessation
- 1980-03-17 NL NL8001568A patent/NL8001568A/en active Search and Examination
- 1980-03-17 GB GB8008979A patent/GB2048250B/en not_active Expired
- 1980-03-18 FR FR8006015A patent/FR2451918A1/en active Granted
1991
- 1991-08-12 JP JP3201754A patent/JPH0627070B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0627070B2 (en)	1994-04-13
GB2048250A (en)	1980-12-10
NL8001568A (en)	1980-09-23
FR2451918A1 (en)	1980-10-17
IT1143012B (en)	1986-10-22
CH646958A5 (en)	1984-12-28
IT8048119A0 (en)	1980-03-10
DE3008693A1 (en)	1980-10-02
FR2451918B1 (en)	1984-01-06
JPH0517451A (en)	1993-01-26

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Legal Events

Date	Code	Title	Description
2000-04-05	PE20	Patent expired after termination of 20 years	Effective date: 20000316