GB1509778A - Pharmaceutical composition and dosage units thereof - Google Patents
Pharmaceutical composition and dosage units thereofInfo
- Publication number
- GB1509778A GB1509778A GB4467775A GB4467775A GB1509778A GB 1509778 A GB1509778 A GB 1509778A GB 4467775 A GB4467775 A GB 4467775A GB 4467775 A GB4467775 A GB 4467775A GB 1509778 A GB1509778 A GB 1509778A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pharmaceutical composition
- dosage units
- bendroflumethazide
- timolol
- antihypertensive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 2
- HDWIHXWEUNVBIY-UHFFFAOYSA-N bendroflumethiazidum Chemical compound C1=C(C(F)(F)F)C(S(=O)(=O)N)=CC(S(N2)(=O)=O)=C1NC2CC1=CC=CC=C1 HDWIHXWEUNVBIY-UHFFFAOYSA-N 0.000 abstract 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N isopropyl alcohol Natural products CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 2
- 229960004605 timolol Drugs 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229960004592 isopropanol Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
1509778 Antihypertensive compositions LEO PHARMACEUTICAL PRODUCTS Ltd AS 12 Oct 1976 [7 Nov 1975] 44677/75 Heading A5B Pharmaceutical compositions having antihypertensive activity comprise bendroflumethazide and S-(-)-1-tert-butylamino-3-(4-morpholino-1, 2, 5-thiadiazol-3-yloxy) - 2 - propanol (timolol) or an acid addition salt thereof, optionally together with a pharmaceutically acceptable carrier, the ratio by weight of the bendroflumethazide to the timolol being between 1:5 and 5:1.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4467775A GB1509778A (en) | 1975-10-29 | 1975-10-29 | Pharmaceutical composition and dosage units thereof |
| IE224076A IE43955B1 (en) | 1975-10-29 | 1976-10-12 | Pharmaceutical composition and dosage units thereof |
| NL7611731A NL187048C (en) | 1975-10-29 | 1976-10-22 | METHOD FOR PREPARING A MEDICINE FOR THE TREATMENT OF EXCESSIVE BLOOD PRESSURE |
| FR7632413A FR2329283A1 (en) | 1975-10-29 | 1976-10-27 | PREPARATION AND PHARMACEUTICAL UNIT FORMS AND THEIR PREPARATION PROCESS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4467775A GB1509778A (en) | 1975-10-29 | 1975-10-29 | Pharmaceutical composition and dosage units thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1509778A true GB1509778A (en) | 1978-05-04 |
Family
ID=10434314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4467775A Expired GB1509778A (en) | 1975-10-29 | 1975-10-29 | Pharmaceutical composition and dosage units thereof |
Country Status (4)
| Country | Link |
|---|---|
| FR (1) | FR2329283A1 (en) |
| GB (1) | GB1509778A (en) |
| IE (1) | IE43955B1 (en) |
| NL (1) | NL187048C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4327080A (en) | 1981-07-13 | 1982-04-27 | E. R. Squibb & Sons, Inc. | Novel Bendroflumethiazide formulations and method |
| EP0154009A1 (en) * | 1983-12-09 | 1985-09-11 | Euro-Celtique S.A. | Use of a thiazide diuretic for the manufacture of a non-diuretic antihypertensive medicament |
-
1975
- 1975-10-29 GB GB4467775A patent/GB1509778A/en not_active Expired
-
1976
- 1976-10-12 IE IE224076A patent/IE43955B1/en not_active IP Right Cessation
- 1976-10-22 NL NL7611731A patent/NL187048C/en not_active IP Right Cessation
- 1976-10-27 FR FR7632413A patent/FR2329283A1/en active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4327080A (en) | 1981-07-13 | 1982-04-27 | E. R. Squibb & Sons, Inc. | Novel Bendroflumethiazide formulations and method |
| AU602899B2 (en) * | 1983-12-07 | 1990-11-01 | Euro-Celtique S.A. | Treatment of hypertension, compounds and compositions for antihypertension and diuresis |
| EP0154009A1 (en) * | 1983-12-09 | 1985-09-11 | Euro-Celtique S.A. | Use of a thiazide diuretic for the manufacture of a non-diuretic antihypertensive medicament |
Also Published As
| Publication number | Publication date |
|---|---|
| IE43955L (en) | 1977-04-29 |
| NL187048B (en) | 1990-12-17 |
| FR2329283A1 (en) | 1977-05-27 |
| NL187048C (en) | 1991-05-16 |
| NL7611731A (en) | 1977-05-03 |
| IE43955B1 (en) | 1981-07-15 |
| FR2329283B1 (en) | 1978-11-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK12184A (en) | Substituted ortho-anisamides, methods of preparing them, compositions containing them and their application as psychotropic agents | |
| ES8500739A1 (en) | Extended action controlled release compositions. | |
| IE45256L (en) | Quinazolone derivatives | |
| DE2862419D1 (en) | Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates | |
| GB1298494A (en) | Phenylethanolamine derivatives | |
| ES485067A1 (en) | Amino or acylamino-substituted pyrimidinyl cephalosporanic acid derivatives and pharmaceutical compositions thereof | |
| IE792241L (en) | Hydroxypropyltriazoles | |
| AU528098B2 (en) | Analgesic tablet | |
| GB1271466A (en) | Thiocarbamic acid derivatives | |
| GB1457546A (en) | Pharmaceutical preparations comprising cephalosporin derivatives | |
| GB1509778A (en) | Pharmaceutical composition and dosage units thereof | |
| GB1525971A (en) | Deodorant composition | |
| GB1421589A (en) | Salicylanilide derivatives | |
| IE34590L (en) | Phenylethanolamine derivatives | |
| GB1500300A (en) | Pharmaceutical preparation for the treatment of circulatory disorders | |
| GB1449404A (en) | N-arylsulphonyl urea derivatives | |
| IE35492B1 (en) | 2-benzylphenols their preparation and compositions containing them | |
| GB1359044A (en) | Quinoline derivatives | |
| ES8303297A1 (en) | New peptide, process for preparation thereof and use thereof. | |
| GB1465771A (en) | Pharmaceutical composition and use thereofd | |
| GB1437788A (en) | Therapeutic compositions | |
| GB1470747A (en) | Pyridazine derivative | |
| GB1287433A (en) | Pharmaceutical compositions | |
| ES8304924A1 (en) | Peptide, process for preparation thereof and use thereof. | |
| GB1471371A (en) | Cyclopenteno-b-pyridine derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 701A | Proceeding under schedule 1 paragraph 4a of the patents act 1977 ** application made to the patents court | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19951012 |