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GB1425238A - Azetidine n-oxides - Google Patents

Azetidine n-oxides

Info

Publication number
GB1425238A
GB1425238A GB1659373A GB1659373A GB1425238A GB 1425238 A GB1425238 A GB 1425238A GB 1659373 A GB1659373 A GB 1659373A GB 1659373 A GB1659373 A GB 1659373A GB 1425238 A GB1425238 A GB 1425238A
Authority
GB
United Kingdom
Prior art keywords
oxides
azetidine
general formula
group
hydrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1659373A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3512472A external-priority patent/JPS48103571A/ja
Priority claimed from JP47035123A external-priority patent/JPS48103563A/ja
Priority claimed from JP2893173A external-priority patent/JPS49116060A/ja
Application filed by Teikoku Hormone Manufacturing Co Ltd filed Critical Teikoku Hormone Manufacturing Co Ltd
Publication of GB1425238A publication Critical patent/GB1425238A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1425238 Azetidine N-oxides TEIKOKU HORMONE MFG CO Ltd 6 April 1973 [10 April 1972 (2) 14 March 1973] 16593/73 Heading C2C Azetidine N-oxides of the general formula or their hydrogen peroxide salts or hydrates, are prepared by oxidizing compounds of general formula wherein R is a saturated or unsaturated substituted or unsubstituted hydrocarbyl group, R 1 is a substituent which is stable to the oxidation, n=0, 1, 2 or 3, and, when n=2 or 3, the R 1 groups may be the same or different. Particular azetidine N-oxides have the general formula wherein Z is an alkyl or aralkyl group and Y is a hydrogen atom or a substituent which is stable to the oxidation. Azetidine N-oxides of the first formula above, or their hydrogen peroxide salts or hydrates, in which R is a saturated or unsaturated substituted or unsubstituted hydrocarbyl group of 1 to 30 carbon atoms and R 1 is a halogen atom or an oxo, alkyl, alkoxy, alkoxyalkyl, alkoxyalkoxy, aryl, aryloxy, aralkyl, aralkoxy, acyloxy, alkoxycarbonyl, aroyloxycarbonyl, aralkoxycarbonyl or organic sulphonyloxy group are claimed as novel. The compounds can be prepared using conventional oxidizing agents.
GB1659373A 1972-04-10 1973-04-06 Azetidine n-oxides Expired GB1425238A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3512472A JPS48103571A (en) 1972-04-10 1972-04-10
JP47035123A JPS48103563A (en) 1972-04-10 1972-04-10
JP2893173A JPS49116060A (en) 1973-03-14 1973-03-14

Publications (1)

Publication Number Publication Date
GB1425238A true GB1425238A (en) 1976-02-18

Family

ID=27286374

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1659373A Expired GB1425238A (en) 1972-04-10 1973-04-06 Azetidine n-oxides

Country Status (3)

Country Link
DE (2) DE2317980A1 (en)
FR (2) FR2179951A1 (en)
GB (1) GB1425238A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379151A (en) 1978-03-14 1983-04-05 A. H. Robins Company, Inc. 3-Phenoxyazetidines for anorexigenic activity
AU661711B2 (en) * 1991-08-20 1995-08-03 Merck Sharp & Dohme Limited Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2280370A1 (en) * 1974-08-01 1976-02-27 Castaigne Sa 1-Acetylene-substd. - azetidines - with sedative antitussive, hypotensive and antiinflammatory activity
DE3418395A1 (en) * 1984-05-17 1985-11-21 Bayer Ag, 5090 Leverkusen BIOLOGICALLY ACTIVE SUBSTITUTES ISOXAZOLIDINE AND NEW ISOXAZOLIDINE AND THEIR PRODUCTION

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379151A (en) 1978-03-14 1983-04-05 A. H. Robins Company, Inc. 3-Phenoxyazetidines for anorexigenic activity
AU661711B2 (en) * 1991-08-20 1995-08-03 Merck Sharp & Dohme Limited Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
FR2179951A1 (en) 1973-11-23
DE2365391A1 (en) 1974-09-26
DE2317980A1 (en) 1973-10-31
FR2213286B3 (en) 1977-01-07
FR2213286A1 (en) 1974-08-02

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Legal Events

Date Code Title Description
CSNS Application of which complete specification have been accepted and published, but patent is not sealed