GB1408437A - Vaccines - Google Patents
VaccinesInfo
- Publication number
- GB1408437A GB1408437A GB4762772A GB4762772A GB1408437A GB 1408437 A GB1408437 A GB 1408437A GB 4762772 A GB4762772 A GB 4762772A GB 4762772 A GB4762772 A GB 4762772A GB 1408437 A GB1408437 A GB 1408437A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vaccine
- oil
- antigenic material
- aqueous phase
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960005486 vaccine Drugs 0.000 title abstract 11
- 230000000890 antigenic effect Effects 0.000 abstract 6
- 239000000463 material Substances 0.000 abstract 6
- 239000008346 aqueous phase Substances 0.000 abstract 5
- 241000283690 Bos taurus Species 0.000 abstract 3
- 241000700605 Viruses Species 0.000 abstract 3
- 241000282465 Canis Species 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 208000002606 Paramyxoviridae Infections Diseases 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 239000003995 emulsifying agent Substances 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- 239000002569 water oil cream Substances 0.000 abstract 2
- 241000282472 Canis lupus familiaris Species 0.000 abstract 1
- 206010012735 Diarrhoea Diseases 0.000 abstract 1
- 241000701915 Feline panleukopenia virus Species 0.000 abstract 1
- 241001280522 Feline picornavirus Species 0.000 abstract 1
- 241000282324 Felis Species 0.000 abstract 1
- 241000282326 Felis catus Species 0.000 abstract 1
- 206010051497 Rhinotracheitis Diseases 0.000 abstract 1
- 230000001804 emulsifying effect Effects 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 208000005562 infectious bovine rhinotracheitis Diseases 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 239000007762 w/o emulsion Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
1408437 Vaccines C-VET Ltd 16 Oct 1973 [16 Oct 1972] 47627/72 Heading A5B A vaccine comprises an antigenic material and is in the form of a multiple oil-water emulsion having a continuous aqueous phase and a primary oil phase in which a secondary aqueous phase is disposed, the concentration of oil in the vaccine being less than 20% by volume, and the percentage of antigenic material in the secondary aqueous phase being from 1 to 20%, the remainder of the antigenic material being present in the continuous aqueous phase. The vaccine may be prepared by subjecting to emulsifying conditions a waterin-oil emulsion containing 1 to 20% of the antigenic material in its aqueous phase, an emulsifying agent and an aqueous medium containing the remainder of the antigenic material, to form a multiple oil-water-emulsion, the proportions of water-in-oil emulsion, emulsifying agent and aqueous medium being such that the concentration of oil in the vaccine is less than 20% by volume. The antigenic material is suitable for the immunisation of domestic animals or livestock. The vaccine may be injected or locally administered to the animal. A vaccine suitabel for immunising cats comprises an antigen derived from feline panleucopenia virus, feline rhinotracheitis virus or feline picornavirus. A vaccine suitable for immunising dogs comprises an antigen derived from canine parainfluenza (SV5-like) virus, or canine adeno (1 and 2) viruses. Cattle may be immunised with a vaccine which comprises a mixture of parainfluenza 3, reo, adeno, bovine diarrhoea and infectious bovine rhinotracheitis. The vaccine may be administered to cattle by more than one injection, the second injection being administered after 1 to 6 weeks.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4762772A GB1408437A (en) | 1972-10-16 | 1972-10-16 | Vaccines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4762772A GB1408437A (en) | 1972-10-16 | 1972-10-16 | Vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1408437A true GB1408437A (en) | 1975-10-01 |
Family
ID=10445683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4762772A Expired GB1408437A (en) | 1972-10-16 | 1972-10-16 | Vaccines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1408437A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991000106A1 (en) * | 1989-07-03 | 1991-01-10 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Injectable multi-phase emulsions |
| US7906311B2 (en) | 2002-03-20 | 2011-03-15 | Merial Limited | Cotton rat lung cells for virus culture |
-
1972
- 1972-10-16 GB GB4762772A patent/GB1408437A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991000106A1 (en) * | 1989-07-03 | 1991-01-10 | Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) | Injectable multi-phase emulsions |
| US7906311B2 (en) | 2002-03-20 | 2011-03-15 | Merial Limited | Cotton rat lung cells for virus culture |
| EP1517987B1 (en) * | 2002-03-20 | 2011-06-01 | Merial Limited | Cotton rat lung cells for virus culture |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |