GB1300291A - Multiple analysis hematology control - Google Patents
Multiple analysis hematology controlInfo
- Publication number
- GB1300291A GB1300291A GB3466570A GB3466570A GB1300291A GB 1300291 A GB1300291 A GB 1300291A GB 3466570 A GB3466570 A GB 3466570A GB 3466570 A GB3466570 A GB 3466570A GB 1300291 A GB1300291 A GB 1300291A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cells
- suspension
- fowl
- saline
- red blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000004027 cell Anatomy 0.000 abstract 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
- 239000011780 sodium chloride Substances 0.000 abstract 4
- 239000000725 suspension Substances 0.000 abstract 4
- 210000003743 erythrocyte Anatomy 0.000 abstract 3
- 239000012530 fluid Substances 0.000 abstract 2
- 239000000644 isotonic solution Substances 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 abstract 1
- 241000272525 Anas platyrhynchos Species 0.000 abstract 1
- 241000272814 Anser sp. Species 0.000 abstract 1
- 239000001263 FEMA 3042 Substances 0.000 abstract 1
- 241000287828 Gallus gallus Species 0.000 abstract 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 abstract 1
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127219 anticoagulant drug Drugs 0.000 abstract 1
- 239000006285 cell suspension Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 210000005260 human cell Anatomy 0.000 abstract 1
- 229960002523 mercuric chloride Drugs 0.000 abstract 1
- LWJROJCJINYWOX-UHFFFAOYSA-L mercury dichloride Chemical compound Cl[Hg]Cl LWJROJCJINYWOX-UHFFFAOYSA-L 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 230000003019 stabilising effect Effects 0.000 abstract 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 abstract 1
- 229940033123 tannic acid Drugs 0.000 abstract 1
- 235000015523 tannic acid Nutrition 0.000 abstract 1
- 229920002258 tannic acid Polymers 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2496/00—Reference solutions for assays of biological material
- G01N2496/05—Reference solutions for assays of biological material containing blood cells or plasma
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
1300291 Haematology control fluid; stabilising fowl red cells PFIZER Inc 17 July 1970 34665/70 Heading B1X Fowl red blood cells are stabilized by a process comprising mixing an 8% suspension of the cells in 0.45% saline with an equal volume of 1% mercuric chloride in 0.45% saline, heating the resulting mixture at 37‹C for about 19 hours, centrifuging and resuspending the cells as a 4% suspension in saline, combining with the cell suspension an equal volume of a 0.0025% solution of tannic acid in 0.45% saline buffered at pH 7.2, incubating for 30 to 60 minutes at about 50‹C, centrifuging, incubating at 0.01 to 20% suspension of the cells in 5.0% glutaraldehyde in an isotonic solution buffered at pH 7.2 at 37‹C for 16-20 hours and washing the cells 3 or 4 times with the buffered isotonic solution, separating the cells by centrifugation after each washing. A hematology control fluid comprises a suspension of fresh human red blood cells and the tanned fowl red blood cells prepared as above in a volume of anticoagulant-containing serologically compatible human plasma medium which is approximately equal to the packed volume of the human cells, the concentration of the fowl cells being 5,000-10,000 per cubic millimeter. The fowl cells may be goose, chicken, duck or (preferably) turkey cells. Reference has been directed by the Comptroller to Specifications 1,131,690 and 1,215,662.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3466570A GB1300291A (en) | 1970-07-17 | 1970-07-17 | Multiple analysis hematology control |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3466570A GB1300291A (en) | 1970-07-17 | 1970-07-17 | Multiple analysis hematology control |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1300291A true GB1300291A (en) | 1972-12-20 |
Family
ID=10368454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3466570A Expired GB1300291A (en) | 1970-07-17 | 1970-07-17 | Multiple analysis hematology control |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1300291A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0317085A3 (en) * | 1987-10-20 | 1989-09-20 | Sumitomo Seika Chemicals Co., Ltd. | Processed red blood cells and process for producing the same |
| CN101374410A (en) * | 2006-01-27 | 2009-02-25 | Bio-Rad实验室公司 | Storage stable cellular whole blood compositions containing elevated amounts of D-dimers |
-
1970
- 1970-07-17 GB GB3466570A patent/GB1300291A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0317085A3 (en) * | 1987-10-20 | 1989-09-20 | Sumitomo Seika Chemicals Co., Ltd. | Processed red blood cells and process for producing the same |
| CN101374410A (en) * | 2006-01-27 | 2009-02-25 | Bio-Rad实验室公司 | Storage stable cellular whole blood compositions containing elevated amounts of D-dimers |
| EP1976375A4 (en) * | 2006-01-27 | 2013-05-01 | Bio Rad Laboratories | WHOLE BLOOD CELL COMPOSITION, STORAGE-STABLE, THAT CONTAINS HIGH QUANTITIES OF D-DIMER |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |