GB1380304A - Imidazole derivatives - Google Patents
Imidazole derivativesInfo
- Publication number
- GB1380304A GB1380304A GB504572A GB504572A GB1380304A GB 1380304 A GB1380304 A GB 1380304A GB 504572 A GB504572 A GB 504572A GB 504572 A GB504572 A GB 504572A GB 1380304 A GB1380304 A GB 1380304A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hcn
- reaction
- formula
- imidazole derivatives
- quimco
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002460 imidazoles Chemical class 0.000 title abstract 2
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1380304 Disubstituted imidazoles QUIMCO GmbH 3 Feb 1972 5045/72 Heading C2C The invention comprises compounds of formula wherein R<SP>1</SP>, R<SP>11</SP> are each (possibly substituted) aliphatic or aromatic radicals, and a process for making them by reacting R<SP>1</SP>R<SP>11</SP>CHCHO under reflux with NH 3 to give which is reacted at below 15‹ C. with HCN giving an iminonitrile this being cyclized by reaction in a polar inert solvent with HCl. If the reaction with HCN is effected at 30-35‹ C., products of formula are obtained.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB504572A GB1380304A (en) | 1972-02-03 | 1972-02-03 | Imidazole derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB504572A GB1380304A (en) | 1972-02-03 | 1972-02-03 | Imidazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380304A true GB1380304A (en) | 1975-01-15 |
Family
ID=9788711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB504572A Expired GB1380304A (en) | 1972-02-03 | 1972-02-03 | Imidazole derivatives |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1380304A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4289905A (en) | 1977-07-19 | 1981-09-15 | Ciba-Geigy Corporation | 2-Aza-1,3-dienes |
| US5359082A (en) * | 1992-03-26 | 1994-10-25 | Basf Aktiengesellschaft | Preparation of 4-substituted imidazoles from N-formyl-α-aminonitrile |
-
1972
- 1972-02-03 GB GB504572A patent/GB1380304A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4289905A (en) | 1977-07-19 | 1981-09-15 | Ciba-Geigy Corporation | 2-Aza-1,3-dienes |
| US5359082A (en) * | 1992-03-26 | 1994-10-25 | Basf Aktiengesellschaft | Preparation of 4-substituted imidazoles from N-formyl-α-aminonitrile |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |