GB1350309A - Acetylsalicylic acid derivative method for its preparation and therapeutic composition containing same - Google Patents
Acetylsalicylic acid derivative method for its preparation and therapeutic composition containing sameInfo
- Publication number
- GB1350309A GB1350309A GB5035671A GB5035671A GB1350309A GB 1350309 A GB1350309 A GB 1350309A GB 5035671 A GB5035671 A GB 5035671A GB 5035671 A GB5035671 A GB 5035671A GB 1350309 A GB1350309 A GB 1350309A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acetylsalicylic acid
- preparation
- composition containing
- acid derivative
- therapeutic composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical class CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 4
- 230000001225 therapeutic effect Effects 0.000 title 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N Arginine Chemical compound OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 2
- 229940068372 acetyl salicylate Drugs 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FXXXGQLMXDIPQA-VWMHFEHESA-N 2-acetyloxybenzoic acid;(2s)-2-amino-5-(diaminomethylideneamino)pentanoic acid Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N.CC(=O)OC1=CC=CC=C1C(O)=O FXXXGQLMXDIPQA-VWMHFEHESA-N 0.000 abstract 1
- 239000004475 Arginine Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229960003121 arginine Drugs 0.000 abstract 1
- 229940110377 dl- arginine Drugs 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/12—Acetic acid esters
- C07C69/14—Acetic acid esters of monohydroxylic compounds
- C07C69/145—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols
- C07C69/157—Acetic acid esters of monohydroxylic compounds of unsaturated alcohols containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1350309 Arginine acetylsalicylate METABIO 29 Oct 1971 [26 Nov 1970] 50356/71 Heading C2C A novel salt of acetylsalicylate is formed by reacting acetylsalicylate with D, L or DL arginine. The reaction is preferably carried out at a temperature below 10‹ C. using acetylsalicylic acid in alcohol or ketone solution and arginine in aqueous solution. The salt has analgesic and antipyrelic properties and with a suitable carrier forms a pharmaceutical composition which may be administered orally or intravenously.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7042535A FR2115059B1 (en) | 1970-11-26 | 1970-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1350309A true GB1350309A (en) | 1974-04-18 |
Family
ID=9064777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5035671A Expired GB1350309A (en) | 1970-11-26 | 1971-10-29 | Acetylsalicylic acid derivative method for its preparation and therapeutic composition containing same |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE2156806C2 (en) |
| FR (1) | FR2115059B1 (en) |
| GB (1) | GB1350309A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0936899A4 (en) * | 1996-06-27 | 2002-01-02 | Procter & Gamble | Cosmetic compositions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1295304A (en) * | 1956-05-07 | 1962-06-08 | Equilibre Biolog L | New salt of acetyl-salicylic acid and its preparation process |
| GB883331A (en) * | 1959-08-28 | 1961-11-29 | Mead Johnson & Co | Stable water-soluble acetylsalicylic acid derivative |
-
1970
- 1970-11-26 FR FR7042535A patent/FR2115059B1/fr not_active Expired
-
1971
- 1971-10-29 GB GB5035671A patent/GB1350309A/en not_active Expired
- 1971-11-16 DE DE19712156806 patent/DE2156806C2/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0936899A4 (en) * | 1996-06-27 | 2002-01-02 | Procter & Gamble | Cosmetic compositions |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2115059B1 (en) | 1974-08-30 |
| DE2156806C2 (en) | 1983-04-28 |
| DE2156806A1 (en) | 1972-05-31 |
| FR2115059A1 (en) | 1972-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |