GB1235589A - Improvements relating to sensing when viscosity of a fluid has risen to a given level - Google Patents
Improvements relating to sensing when viscosity of a fluid has risen to a given levelInfo
- Publication number
- GB1235589A GB1235589A GB30360/69A GB3036069A GB1235589A GB 1235589 A GB1235589 A GB 1235589A GB 30360/69 A GB30360/69 A GB 30360/69A GB 3036069 A GB3036069 A GB 3036069A GB 1235589 A GB1235589 A GB 1235589A
- Authority
- GB
- United Kingdom
- Prior art keywords
- viscosity
- sample
- relay
- reagent
- ball
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000012530 fluid Substances 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 4
- PGOHTUIFYSHAQG-LJSDBVFPSA-N (2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O PGOHTUIFYSHAQG-LJSDBVFPSA-N 0.000 abstract 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical group [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 102000002262 Thromboplastin Human genes 0.000 abstract 1
- 108010000499 Thromboplastin Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 230000000881 depressing effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Ecology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1,235,589. Testing viscosity. BAXTER LABORATORIES Inc. June 16, 1969 [June 17, 1968], No. 30360/69. Heading G1S. [Also in Division G4] In order to measure the time taken for the viscosity of a sample Fig. 1 to rise to a predetermined level after a reagent is added, a spherical ball 18 is magnetically 14, 16 suspended in the sample, the sample is reciprocated 12 in a vertical direction, and constant frequency clock-pulses are counted from the instant of adding the reagent until the viscosity has risen to the predetermined level, this being detected photo-electrically 20, 22 (or by inductive means, not described). As described the sample is blood to which thromboplastin has already been added, and the reagent is calcium chloride. In operation the sample, containing the ball, is placed in a well 40, Fig.2, of atemperature controlled block 30. The ball then rises to the level of the magnet 14, 16 and blocks the light path 20, 22, Figs.2, 6, thereby energizing a relay K1 (shown de-energized) to start a reciprocating drive motor 44 and a 10c/s clock-pulse generator motor 108 details Fig. 5 (not shown). Addition of a measured quantity of reagent is effected by depressing a cylinder 54, Fig.2, to thereby close a switch 66, Figs.2, 6, and energize a second relay K2, which holds over its lower contact and allows clock-pulses to pass over its upper contacts to a counter 250. Eventually, when the viscosity has risen, the ball is dragged from its position between the magnets 14, 16, the light path 20, 22 is cleared, and relay K1 is de-energized to break the hold circuit for relay K2 and the counting is stopped. Dimensions and components of a preferred embodiment are given in the Specification.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73838268A | 1968-06-17 | 1968-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1235589A true GB1235589A (en) | 1971-06-16 |
Family
ID=24967756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB30360/69A Expired GB1235589A (en) | 1968-06-17 | 1969-06-16 | Improvements relating to sensing when viscosity of a fluid has risen to a given level |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5014919B1 (en) |
| BE (1) | BE734598A (en) |
| DE (1) | DE1930270C3 (en) |
| FR (1) | FR2011058A1 (en) |
| GB (1) | GB1235589A (en) |
| IL (1) | IL32423A (en) |
| SE (1) | SE366117B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0970742A3 (en) * | 1998-07-09 | 2002-01-23 | Ral Tecnica para el Laboratorio, S.A. | Improved agitator device |
| RU2265204C2 (en) * | 2003-04-14 | 2005-11-27 | Муниципальное общеообразовательное учреждение лицей № 11 | Viscosity meter |
| WO2006125057A1 (en) * | 2005-05-16 | 2006-11-23 | Haemoscope Corporation | Hemostasis analysis device and method |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5169062U (en) * | 1974-11-28 | 1976-06-01 | ||
| JPS5312517U (en) * | 1976-07-15 | 1978-02-02 | ||
| FR2383444A1 (en) * | 1977-03-11 | 1978-10-06 | Laborgeraete Analysensyst Gmbh | MEASURING BLOOD COAGULATION TIME |
| DE3127560C2 (en) * | 1981-07-11 | 1993-01-14 | Jochimsen, Siegfried, 2300 Kiel | Device for recording and measuring blood clotting time with a temperature-controlled metal block for holding the measuring cuvette, a stirring device and a light-optical turbidity measuring device |
| EP0083617A1 (en) * | 1981-07-11 | 1983-07-20 | JOCHIMSEN, Siegfried | Apparatus for measuring the bloot clotting time and method for taking and measuring the time |
| FR2516658B1 (en) * | 1981-11-19 | 1987-06-26 | Behnk Holger | APPARATUS AND METHOD FOR DETECTING AND MEASURING BLOOD COAGULATION TIME |
| AT375191B (en) * | 1982-08-10 | 1984-07-10 | Foissy Helmut Dipl Ing Dr | COAGULOMETER FOR DETERMINING THE HEAT STABILITY OF MILK |
| FR3030048B1 (en) * | 2014-12-15 | 2016-12-23 | Immunodiagnostic Systems France | METHOD AND DEVICE FOR DETERMINING THE COAGULATION TIME OF A BLOOD SAMPLE AND REACTION CUP |
| EP3685064B1 (en) * | 2017-09-19 | 2024-03-27 | Renault s.a.s | Protective bellows for the clutch housing of a motor vehicle supporting the hydraulic drive connector of a clutch slave cylinder |
| KR102773544B1 (en) * | 2020-05-11 | 2025-02-25 | 현대모비스 주식회사 | Method And Apparatus for Use in Vehicle Brake System |
-
1969
- 1969-06-04 JP JP44043935A patent/JPS5014919B1/ja active Pending
- 1969-06-13 DE DE1930270A patent/DE1930270C3/en not_active Expired
- 1969-06-16 BE BE734598D patent/BE734598A/xx unknown
- 1969-06-16 GB GB30360/69A patent/GB1235589A/en not_active Expired
- 1969-06-16 FR FR6919897A patent/FR2011058A1/fr not_active Withdrawn
- 1969-06-16 SE SE08572/69A patent/SE366117B/xx unknown
- 1969-06-19 IL IL32423A patent/IL32423A/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0970742A3 (en) * | 1998-07-09 | 2002-01-23 | Ral Tecnica para el Laboratorio, S.A. | Improved agitator device |
| RU2265204C2 (en) * | 2003-04-14 | 2005-11-27 | Муниципальное общеообразовательное учреждение лицей № 11 | Viscosity meter |
| WO2006125057A1 (en) * | 2005-05-16 | 2006-11-23 | Haemoscope Corporation | Hemostasis analysis device and method |
Also Published As
| Publication number | Publication date |
|---|---|
| BE734598A (en) | 1969-12-01 |
| FR2011058A1 (en) | 1970-02-27 |
| DE1930270B2 (en) | 1975-04-03 |
| SE366117B (en) | 1974-04-08 |
| IL32423A0 (en) | 1969-08-27 |
| IL32423A (en) | 1974-09-10 |
| DE1930270C3 (en) | 1975-11-13 |
| DE1930270A1 (en) | 1969-12-18 |
| JPS5014919B1 (en) | 1975-05-31 |
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