GB1264128A - - Google Patents
Info
- Publication number
- GB1264128A GB1264128A GB3123268A GB1264128DA GB1264128A GB 1264128 A GB1264128 A GB 1264128A GB 3123268 A GB3123268 A GB 3123268A GB 1264128D A GB1264128D A GB 1264128DA GB 1264128 A GB1264128 A GB 1264128A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- alkyl
- optionally substituted
- halogen atoms
- phenyl optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 239000002262 Schiff base Substances 0.000 abstract 1
- 150000004753 Schiff bases Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003152 propanolamines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,264,128. Propanolamine derivatives. PFIZER Ltd. 4 Sept., 1969 [29 June, 1968], No. 31232/68. Heading C2C. Compounds of the general formula (Ph = phenyl optionally substituted by one or more halogen atoms or C 1-4 alkyl, C 1-4 alkoxy, CF 3 or benzyloxy groups; Ph<SP>1</SP> = phenyl optionally substituted by one or more halogen atoms or C 1-4 alkyl or alkoxy groups. R<SP>1</SP> = H, C 1-4 alkyl, benzyl; R<SP>2,3</SP> = H or C 1-4 alkyl; n = 1 or 2) and their acid addition salts are prepared by (a) reacting (X = leaving atom or group) with (b) reacting with (c) reacting with or (d) reacting with and catalytically hydrogenating the resulting Schiff base, optionally followed in each case by salt formation. The above compounds are #-adrenergic blocking agents and/or hypotensive agents, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. Reference has been directed by the Comptroller to Specification 1,123,258.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3123268 | 1968-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1264128A true GB1264128A (en) | 1972-02-16 |
Family
ID=10320023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3123268A Expired GB1264128A (en) | 1968-06-29 | 1968-06-29 |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1264128A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2367054A1 (en) * | 1976-10-07 | 1978-05-05 | Haessle Ab | ORTHO AND N- DERIVATIVES OF PHENOXY-AMINO-PROPANOL AND THEIR APPLICATION AS CARDIOTONIC COMPOUNDS |
-
1968
- 1968-06-29 GB GB3123268A patent/GB1264128A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2367054A1 (en) * | 1976-10-07 | 1978-05-05 | Haessle Ab | ORTHO AND N- DERIVATIVES OF PHENOXY-AMINO-PROPANOL AND THEIR APPLICATION AS CARDIOTONIC COMPOUNDS |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |