GB1264197A - - Google Patents
Info
- Publication number
- GB1264197A GB1264197A GB1264197DA GB1264197A GB 1264197 A GB1264197 A GB 1264197A GB 1264197D A GB1264197D A GB 1264197DA GB 1264197 A GB1264197 A GB 1264197A
- Authority
- GB
- United Kingdom
- Prior art keywords
- salts
- esters
- compositions
- hypolipemic
- inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- -1 alkali metal salts Chemical class 0.000 abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 2
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000004856 capillary permeability Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000000810 peripheral vasodilating agent Substances 0.000 abstract 1
- 229960002116 peripheral vasodilator Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
1,264,197. Anti-inflammatory, hypolipemic &c. medicines. ROUSSEL UCLAF. 18 July, 1969 [11 June, 1969], No. 36382/69. Heading A5B. [Also in Division C2] Pharmaceutical compositions comprise thiazolecarboxylic acids of the formula: wherein R<SP>2</SP> is a straight chain alkyl group containing from 1 to 12 carbon atoms and/or salts and/or esters thereof, the said salts being alkali metal salts or acid addition salts with organic bases and the said esters being esters of substituted or unsubstituted alkanols, in association with pharmaceutical carriers or excipients. The compositions are in a form suitable for oral, rectal or transcutaneous administration and have hypolipemic, anti-inflammatory and sustained vasodilatory activities. In addition to the above active ingredients the compositions may contain further physiologically active ingredients, for example, peripheral vasodilators, regulators of capillary permeability or spasmolytics.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR696919339A FR2047876B1 (en) | 1969-06-11 | 1969-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1264197A true GB1264197A (en) | 1972-02-16 |
Family
ID=9035547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1264197D Expired GB1264197A (en) | 1969-06-11 | 1969-07-18 |
Country Status (11)
| Country | Link |
|---|---|
| BE (1) | BE736219A (en) |
| BR (1) | BR6910855D0 (en) |
| CA (1) | CA943545A (en) |
| CH (1) | CH513909A (en) |
| DE (1) | DE1966948C2 (en) |
| DK (1) | DK140256B (en) |
| ES (1) | ES369646A1 (en) |
| FR (1) | FR2047876B1 (en) |
| GB (1) | GB1264197A (en) |
| IL (1) | IL32616A (en) |
| NL (1) | NL157801B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2228483A2 (en) * | 1973-05-11 | 1974-12-06 | Roussel Uclaf | Esters and salts of 2-propylthiazole-5-carboxylic acid - vasodilators and hypolipidaemics |
| FR2289189A1 (en) * | 1974-10-29 | 1976-05-28 | Roussel Uclaf | NEW DERIVATIVES OF 2-HYDROXYALKYL THIAZOL 5-CARBOXYL ACIDS, THEIR PROCESS FOR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
-
1969
- 1969-06-11 FR FR696919339A patent/FR2047876B1/fr not_active Expired
- 1969-07-14 IL IL32616A patent/IL32616A/en unknown
- 1969-07-16 CA CA057,213*7A patent/CA943545A/en not_active Expired
- 1969-07-17 BE BE736219D patent/BE736219A/xx not_active IP Right Cessation
- 1969-07-17 ES ES369646A patent/ES369646A1/en not_active Expired
- 1969-07-17 CH CH1095569A patent/CH513909A/en not_active IP Right Cessation
- 1969-07-17 DK DK387269AA patent/DK140256B/en not_active IP Right Cessation
- 1969-07-18 GB GB1264197D patent/GB1264197A/en not_active Expired
- 1969-07-18 BR BR210855/69A patent/BR6910855D0/en unknown
- 1969-07-18 DE DE1966948A patent/DE1966948C2/en not_active Expired
- 1969-07-18 NL NL6911060.A patent/NL157801B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL157801B (en) | 1978-09-15 |
| IL32616A (en) | 1974-03-14 |
| BR6910855D0 (en) | 1973-05-10 |
| IL32616A0 (en) | 1969-09-25 |
| NL6911060A (en) | 1970-12-15 |
| DK140256B (en) | 1979-07-16 |
| DK140256C (en) | 1979-12-17 |
| DE1966948C2 (en) | 1983-04-21 |
| ES369646A1 (en) | 1971-06-01 |
| FR2047876A1 (en) | 1971-03-19 |
| FR2047876B1 (en) | 1973-03-16 |
| CH513909A (en) | 1971-10-15 |
| BE736219A (en) | 1970-01-19 |
| CA943545A (en) | 1974-03-12 |
| DE1966948A1 (en) | 1975-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |