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GB1242863A - 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF - Google Patents

2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF

Info

Publication number
GB1242863A
GB1242863A GB2222368A GB2222368A GB1242863A GB 1242863 A GB1242863 A GB 1242863A GB 2222368 A GB2222368 A GB 2222368A GB 2222368 A GB2222368 A GB 2222368A GB 1242863 A GB1242863 A GB 1242863A
Authority
GB
United Kingdom
Prior art keywords
signify
alkoxy
alkyl
quinazolines
thiazolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2222368A
Inventor
Kurt Rubinstein
Erik Falch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia AS
Original Assignee
Pharmacia AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AS filed Critical Pharmacia AS
Priority to GB2222368A priority Critical patent/GB1242863A/en
Publication of GB1242863A publication Critical patent/GB1242863A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/16—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

1,242,863. Anti-inflammatory &c. medicines. PHARMACIA AS. 9 May, 1969 [10 May, 1968], No. 22223/68. Heading A5B. [Also in Division C2] Pharmaceutical preparations showing, in particular, anti-inflammatory, analgesic, hypothermic and sedative properties, contain as active ingredient compounds I (including salts and hydrates thereof) wherein X is O, S, NH or alkylidene (especially CH 2 ), R 1 and R 2 signify H, alkyl or alkoxy or R 1 and R 3 together signify alkylidene, R 3 and R 4 signify H, OH, alkyl, alkoxy, CO 2 H, alkoxycarbonyl or CONH 2 and R 5 , R 6 , R 7 and R 8 signify H, halogen, CF 3 , OH, alkyl, alkoxy, alkylthio, CO 2 H, alkoxycarbonyl, CONH 2 , NO 2 CN, NH 2 or dialkylamino. Administration may be orally, parenterally or topically and the other actives can be incorporated in the preparations.
GB2222368A 1968-05-10 1968-05-10 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF Expired GB1242863A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2222368A GB1242863A (en) 1968-05-10 1968-05-10 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2222368A GB1242863A (en) 1968-05-10 1968-05-10 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF

Publications (1)

Publication Number Publication Date
GB1242863A true GB1242863A (en) 1971-08-18

Family

ID=10175918

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2222368A Expired GB1242863A (en) 1968-05-10 1968-05-10 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF

Country Status (1)

Country Link
GB (1) GB1242863A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128647A (en) * 1978-03-24 1978-12-05 E. R. Squibb & Sons, Inc. Substituted thiazolo [3,2-a]-thiopyrano[4,3-d]pyrimidines
US4128648A (en) * 1978-03-24 1978-12-05 E. R. Squibb & Sons, Inc. Substituted pyrano[4,3-d]-thiazolo[3,2-a]pyrimidines
US4332802A (en) * 1975-12-19 1982-06-01 Boehringer Ingelheim Kg 11-Oxo-11H-pyrido[2,1-b]quinazoline-2-carboxylic acid and salts thereof, antiallergic compositions containing it and methods of suppressing allergic reactions with it
US4486221A (en) * 1981-10-28 1984-12-04 Basf Aktiengesellschaft Thiazolo[2,3-b]quinazolones and their use for influencing plant growth
US5028705A (en) * 1987-09-11 1991-07-02 Basf Aktiengesellschaft Preparation of pyrazolo[5,1-b]quinazolones
EP0564397A1 (en) * 1992-03-03 1993-10-06 Sandoz Ltd. Antiatherosclerotic substituted phenylquinazoline derivatives
DE10046728C1 (en) * 2000-09-21 2001-09-27 Ibfb Gmbh Privates Inst Fuer B New mercaptomethyl-substituted tricyclic quinazolinone derivatives, are matrix metalloprotease inhibitors useful for treating cancer, rheumatism, inflammatory reactions or allergies
CN108472267A (en) * 2015-12-01 2018-08-31 宝洁公司 Compounds and methods for for inhibiting trimethylamine to generate

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4332802A (en) * 1975-12-19 1982-06-01 Boehringer Ingelheim Kg 11-Oxo-11H-pyrido[2,1-b]quinazoline-2-carboxylic acid and salts thereof, antiallergic compositions containing it and methods of suppressing allergic reactions with it
US4128647A (en) * 1978-03-24 1978-12-05 E. R. Squibb & Sons, Inc. Substituted thiazolo [3,2-a]-thiopyrano[4,3-d]pyrimidines
US4128648A (en) * 1978-03-24 1978-12-05 E. R. Squibb & Sons, Inc. Substituted pyrano[4,3-d]-thiazolo[3,2-a]pyrimidines
US4486221A (en) * 1981-10-28 1984-12-04 Basf Aktiengesellschaft Thiazolo[2,3-b]quinazolones and their use for influencing plant growth
US5028705A (en) * 1987-09-11 1991-07-02 Basf Aktiengesellschaft Preparation of pyrazolo[5,1-b]quinazolones
EP0564397A1 (en) * 1992-03-03 1993-10-06 Sandoz Ltd. Antiatherosclerotic substituted phenylquinazoline derivatives
DE10046728C1 (en) * 2000-09-21 2001-09-27 Ibfb Gmbh Privates Inst Fuer B New mercaptomethyl-substituted tricyclic quinazolinone derivatives, are matrix metalloprotease inhibitors useful for treating cancer, rheumatism, inflammatory reactions or allergies
CN108472267A (en) * 2015-12-01 2018-08-31 宝洁公司 Compounds and methods for for inhibiting trimethylamine to generate

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