GB1114083A - Process for producing inosinic acid - Google Patents
Process for producing inosinic acidInfo
- Publication number
- GB1114083A GB1114083A GB3170866A GB3170866A GB1114083A GB 1114083 A GB1114083 A GB 1114083A GB 3170866 A GB3170866 A GB 3170866A GB 3170866 A GB3170866 A GB 3170866A GB 1114083 A GB1114083 A GB 1114083A
- Authority
- GB
- United Kingdom
- Prior art keywords
- inosinic acid
- guanosine
- derivatives
- hypoxanthine
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Inosinic acid is prepared by a fermentation process which comprises culturing an adeninerequiring microorganism capable of producing inosinic acid in an aqueous nutrient medium containing adenine and, at least, a source of carbon and nitrogen in the presence of at least one of the compounds selected from the group consisting of guanine, hypoxanthine, guanosine, inosine, ribonucleic acid hydrolysate, derivatives of guanosine and derivatives of hypoxanthine under aerobic conditions at a temperature of from about 25-38 DEG C. and a pH of about 5.5-8.5. The culture medium may be synthetic or natural and may also contain inorganic compounds such as magnesium sulphate, sodium phosphate, potassium mono- or dihydrogen phosphate, iron sulphate or other iron salts, manganese chloride and calcium chloride. Biotin and/or other appropriate vitamins may also be present. After fermenting, suitably for 2-3 days, the inosinic acid may be recovered by conventional means such as ion exchange treatment, solvent extraction, precipitation with metallic salts or chromatography. Specific micro-organisms used are Micrococcus glutamicus, Brevibacterium ammoniagenes and Bacillus subtilis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4322665 | 1965-07-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1114083A true GB1114083A (en) | 1968-05-15 |
Family
ID=12657983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3170866A Expired GB1114083A (en) | 1965-07-19 | 1966-07-14 | Process for producing inosinic acid |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE1517826B1 (en) |
| GB (1) | GB1114083A (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB979141A (en) * | 1960-11-11 | 1965-01-01 | Kyowa Hakko Kogyo Kk | A method for manufacturing inosinic acid by fermentation |
| FR1307352A (en) * | 1961-09-14 | 1962-10-26 | Kyowa Hakko Kogyo Kk | Process for preparing inosinic acid by fermentation |
-
1966
- 1966-07-14 GB GB3170866A patent/GB1114083A/en not_active Expired
- 1966-07-19 DE DE19661517826 patent/DE1517826B1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE1517826B1 (en) | 1970-04-16 |
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