GB1100267A - 9-amino-5-o-desosaminyl-3,6,11,12-tetrahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide and 9-amino-3,5,6,11,12-pentahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide - Google Patents
9-amino-5-o-desosaminyl-3,6,11,12-tetrahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide and 9-amino-3,5,6,11,12-pentahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olideInfo
- Publication number
- GB1100267A GB1100267A GB4608266A GB4608266A GB1100267A GB 1100267 A GB1100267 A GB 1100267A GB 4608266 A GB4608266 A GB 4608266A GB 4608266 A GB4608266 A GB 4608266A GB 1100267 A GB1100267 A GB 1100267A
- Authority
- GB
- United Kingdom
- Prior art keywords
- olide
- amino
- hexamethylpentadecane
- desosaminyl
- pentahydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PYIZPAMUFWYMAO-UHFFFAOYSA-N 10-amino-14-ethyl-4,6,7,12,13-pentahydroxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one Chemical compound NC1C(CC(C(C(C(C(C(=O)OC(C(C(C1C)O)(C)O)CC)C)O)C)O)(C)O)C PYIZPAMUFWYMAO-UHFFFAOYSA-N 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The novel compounds 9-amino-5-0-desosaminyl - 3,6,11,12 - tetrahydroxy - 2,4,6,8,10-12 - hexamethylpentadecane - 13 - olide (I) and 9 - amino - 3,5,6,11,12 - pentahydroxy-2,4,6,8,10,12 - hexamethyl - pentadecane - 13 - olide (II), are prepared by hydrolysing 9-amino-3 - 0 - cladinosyl - 5 - 0 - desosaminyl - 6,11,12-trihydroxy - 2,4,6,8,10,12 - hexamethyl - pentadecane-13-olide with 1% hydrochloric acid solution in methanol to prepare (I), and with 2N hydrochloric acid to prepare (II).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4608266A GB1100267A (en) | 1966-10-14 | 1966-10-14 | 9-amino-5-o-desosaminyl-3,6,11,12-tetrahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide and 9-amino-3,5,6,11,12-pentahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4608266A GB1100267A (en) | 1966-10-14 | 1966-10-14 | 9-amino-5-o-desosaminyl-3,6,11,12-tetrahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide and 9-amino-3,5,6,11,12-pentahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1100267A true GB1100267A (en) | 1968-01-24 |
Family
ID=10439786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4608266A Expired GB1100267A (en) | 1966-10-14 | 1966-10-14 | 9-amino-5-o-desosaminyl-3,6,11,12-tetrahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide and 9-amino-3,5,6,11,12-pentahydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1100267A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939144A (en) * | 1974-01-14 | 1976-02-17 | Pliva, Pharmaceutical And Chemical Works | Manufacture of N-(benzenesulfonyl)-5-O-desosaminyl-erythromycilamine derivatives |
-
1966
- 1966-10-14 GB GB4608266A patent/GB1100267A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939144A (en) * | 1974-01-14 | 1976-02-17 | Pliva, Pharmaceutical And Chemical Works | Manufacture of N-(benzenesulfonyl)-5-O-desosaminyl-erythromycilamine derivatives |
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