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GB1035092A - Improvements relating to herbicides and novel 3-substituted uracils - Google Patents

Improvements relating to herbicides and novel 3-substituted uracils

Info

Publication number
GB1035092A
GB1035092A GB619166A GB619166A GB1035092A GB 1035092 A GB1035092 A GB 1035092A GB 619166 A GB619166 A GB 619166A GB 619166 A GB619166 A GB 619166A GB 1035092 A GB1035092 A GB 1035092A
Authority
GB
United Kingdom
Prior art keywords
radical
carbon atoms
radical containing
alkyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB619166A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US217521A external-priority patent/US3235357A/en
Priority claimed from US221890A external-priority patent/US3235358A/en
Priority claimed from US232311A external-priority patent/US3235360A/en
Priority claimed from US233952A external-priority patent/US3235361A/en
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of GB1035092A publication Critical patent/GB1035092A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Novel compounds of the general formula <FORM:1035092/C2/1> or the corresponding isomeric formula <FORM:1035092/C2/2> wherein R1 represents a cycloalkyl alkyl radical containing 4 to 13 carbon atoms, a cycloalkenyl alkyl radical containing 5 to 13 carbon atoms, a (substituted cycloalkyl)alkyl radical containing 5 to 14 carbon atoms or a (substituted cycloalkenyl)alkyl radical containing 5 to 14 carbon atoms; R2 represents a hydrogen, chlorine, fluorine, bromine or iodine atom, a methyl radical, an ethyl radical, a propyl radical, a butyl radical, a methoxy radical, an ethoxy radical, a propoxy radical, a butoxy radical, a nitro radical, an alkoxymethyl radical containing 2 to 6 carbon atoms, a hydroxy alkyl radical containing 1 to 6 carbon atoms, an alkenyl radical containing 3 to 6 carbon atoms, a thiocyanato radical, a cyano radical, a mercaptomethyl radical, a methylthiomethyl radical, a phenylthiomethyl radical, an alkylthio radical containing 1 to 4 carbon atoms, a bromomethyl radical, a fluoromethyl radical, a chloromethyl radical or a carboxymethylthiomethyl radical; R3 represents a hydrogen, chlorine or bromine atom, an alkyl radical containing 1 to 5 carbon atoms, a chloroalkyl radical containing 1 to 4 carbon atoms, a bromoalkyl radical containing 1 to 4 carbon atoms, or an alkoxy radical containing 1 to 5 carbon atoms; or R2 and R3 together represent a divalent alkylene radical of formula (CH2)n, where n is 3, 4 or 5; with the proviso that if R2 represents hydrogen, R3 represents hydrogen or C1- 5 alkyl; and X represents an oxygen or sulphur atom or a metal salt thereof, are prepared by methods known for the production of uracils, e.g. those disclosed in 968,661. These compounds are herbicides (see Division A5). Intermediates. - Ethyl 2 - (3 - cyclopropylmethylureido) - 1 - cycloheptene - 1 - carboxylate is prepared from cyclopropylmethyl urea and ethyl 2 - cycloheptanone - 1 - carboxylate. 6 - Carboxy -3 - (4 - methoxycyclohexylmethyl)-5-methyluracil is prepared from 1-(4-methoxycyclohexylmethyl) urea and diethyl 2-methyloxalacetate. [(3 - Norbornenylmethylureido)-methylene]malononitrile is prepared from norbornenylmethylurea, malononitrile and triethyl orthoformate; with methanolic NaOMe, followed by acetic acid, it gives 3-norbornenylmethyl-5-cyanocytosine.ALSO:Compounds of the general formula: <FORM:1035092/A5-A6/1> or the corresponding isomeric formula: <FORM:1035092/A5-A6/2> wherein R1 represents a cycloalkyl alkyl radical containing 4 to 13 carbon atoms, a cycloalkenyl alkyl radical containing 5 to 13 carbon atoms, a (substituted cycloalkyl)alkyl radical containing 5 to 14 carbon atoms or a (substituted cycloalkenyl) alkyl radical containing 5 to 14 carbon atoms; R2 represents a hydrogen, chlorine, fluorine, bromine or iodine atom, a methyl radical, an ethyl radical, a propyl radical, a butyl radical, a methoxy radical, an ethoxy radical, a propoxy radical, a butoxy radical, a nitro radical, an alkoxymethyl radical containing 2 to 6 carbon atoms, a hydroxy alkyl radical containing 1 to 6 carbon atoms, an alkenyl radical containing 3 to 6 carbon atoms, a thiocyanato radical, a cyano radical, a mercaptomethyl radical, a methylthiomethyl radical, a phenylthiomethyl radical, an alkylthio radical containing 1 to 4 carbon atoms, a bromomethyl radical, a fluoromethyl radical, a chloromethyl radical or a carboxymethylthiomethyl radical; R3 represents a hydrogen, chlorine or bromine atom, an alkyl radical containing 1 to 5 carbon atoms, a chloroalkyl radical containing 1 to 4 carbon atoms a bromoalkyl radical containing 1 to 4 carbon atoms, or an alkoxy radical containing 1 to 5 carbon atoms; or R2 and R3 together represent a divalent alkylene radical of formula (CH2)n, where n is 3, 4 or 5; with the proviso that if R2 represents hydrogen, R3 represent hydrogen or C1-5 alkyl; and X represents an oxyten or sulphur atom or a metal salt thereof, are used to control the growth of weeds, e.g. in a composition containing additionally (i) a diluent which is at least in part an oil (defined as a liquid immiscible with water and soluble in ether, and boiling at not below 125 DEG C), with or without a surface-active agent; (ii) a diluent which is at least in part a solid, with or without a surface-active agent; (iii) a surface-active agent and a diluent which is a liquid other than an oil, e.g. water; or (iv) a surface-active agent. The compositions may be in the form of solutions, dispersions, powders or dusts, granules or pellets, and may contain adhesives, corrosion inhibitors, antifoam agents, dyes, pigments, anticaking agents, hard water stabilizers and other herbicides, e.g. those of Specifications 1,035,091, 1,035,093, 1,035,094, 1,035,095, 1,035,096, 1,035,097 or 1,035,098, or substituted ureas, substituted triazines, phenols, chloro-carboxylic acids and their derivatives, substituted carbamic acid derivatives, maleic hydrazide, inorganic salts, mixed inorganic-organic salts, or other specified herbicides.
GB619166A 1959-08-14 1962-12-07 Improvements relating to herbicides and novel 3-substituted uracils Expired GB1035092A (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US83370459A 1959-08-14 1959-08-14
US83370559A 1959-08-14 1959-08-14
US1295660A 1960-03-07 1960-03-07
US1295860A 1960-03-07 1960-03-07
US1295760A 1960-03-07 1960-03-07
US1295960A 1960-03-07 1960-03-07
US1296760A 1960-03-07 1960-03-07
US1296860A 1960-03-07 1960-03-07
US4883760A 1960-08-11 1960-08-11
US8498061A 1961-01-26 1961-01-26
US8967461A 1961-02-16 1961-02-16
US12363661A 1961-07-13 1961-07-13
US15974661A 1961-12-15 1961-12-15
US16743462A 1962-01-19 1962-01-19
US217521A US3235357A (en) 1959-08-14 1962-08-17 Method for the control of undesirable vegetation
US221890A US3235358A (en) 1962-09-06 1962-09-06 Control of undesirable vegetation
US232311A US3235360A (en) 1959-08-14 1962-10-22 Control of undesirable vegetation
US233952A US3235361A (en) 1962-10-29 1962-10-29 Method for the control of undesirable vegetation
US284835A US3254082A (en) 1959-08-14 1963-06-03 Process for preparing substituted uracils

Publications (1)

Publication Number Publication Date
GB1035092A true GB1035092A (en) 1966-07-06

Family

ID=27586287

Family Applications (1)

Application Number Title Priority Date Filing Date
GB619166A Expired GB1035092A (en) 1959-08-14 1962-12-07 Improvements relating to herbicides and novel 3-substituted uracils

Country Status (1)

Country Link
GB (1) GB1035092A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077297A (en) * 1988-04-22 1991-12-31 Imperial Chemical Industries Plc Novel compounds
US5104878A (en) * 1989-04-17 1992-04-14 Imperial Chemical Industries Plc 1-phenyl-6-one-pyrimidine derivatives
US5149810A (en) * 1988-04-22 1992-09-22 Imperial Chemical Industries Plc Pyrimidine compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077297A (en) * 1988-04-22 1991-12-31 Imperial Chemical Industries Plc Novel compounds
US5149810A (en) * 1988-04-22 1992-09-22 Imperial Chemical Industries Plc Pyrimidine compounds
US5104878A (en) * 1989-04-17 1992-04-14 Imperial Chemical Industries Plc 1-phenyl-6-one-pyrimidine derivatives

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