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GB0801674D0 - Compounds having CRTH2 antagonist activity - Google Patents

Compounds having CRTH2 antagonist activity

Info

Publication number
GB0801674D0
GB0801674D0 GBGB0801674.3A GB0801674A GB0801674D0 GB 0801674 D0 GB0801674 D0 GB 0801674D0 GB 0801674 A GB0801674 A GB 0801674A GB 0801674 D0 GB0801674 D0 GB 0801674D0
Authority
GB
United Kingdom
Prior art keywords
compounds
antagonist activity
crth2 antagonist
crth2
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB0801674.3A
Other versions
GB2457040A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROBERTS ALISON C
Original Assignee
ROBERTS ALISON C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROBERTS ALISON C filed Critical ROBERTS ALISON C
Priority to GB0801674A priority Critical patent/GB2457040A/en
Publication of GB0801674D0 publication Critical patent/GB0801674D0/en
Publication of GB2457040A publication Critical patent/GB2457040A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB0801674A 2008-01-30 2008-01-30 1-Acetic acid indole derivatives with PGD2 activity Pending GB2457040A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB0801674A GB2457040A (en) 2008-01-30 2008-01-30 1-Acetic acid indole derivatives with PGD2 activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0801674A GB2457040A (en) 2008-01-30 2008-01-30 1-Acetic acid indole derivatives with PGD2 activity

Publications (2)

Publication Number Publication Date
GB0801674D0 true GB0801674D0 (en) 2008-03-05
GB2457040A GB2457040A (en) 2009-08-05

Family

ID=39186569

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0801674A Pending GB2457040A (en) 2008-01-30 2008-01-30 1-Acetic acid indole derivatives with PGD2 activity

Country Status (1)

Country Link
GB (1) GB2457040A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
WO2014026959A1 (en) * 2012-08-13 2014-02-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for treatment of cystic fibrosis
CN103588697B (en) * 2012-08-14 2017-09-15 中国科学院上海药物研究所 Disubstituted benzenes sulfamide compound of one class 2,5 and its production and use
JP7763510B2 (en) * 2021-09-03 2025-11-04 深▲セン▼零一生命科技有限責任公司 Indole compounds, their preparation and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557142A (en) * 1968-02-20 1971-01-19 Sterling Drug Inc 4,5,6,7-tetrahydro-indole-lower-alkanoic acids and esters
KR100584650B1 (en) * 1998-03-31 2006-05-30 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 Substituted indolalkanoic acids
EP2046740B1 (en) * 2006-07-22 2012-05-23 Oxagen Limited Compounds having crth2 antagonist activity

Also Published As

Publication number Publication date
GB2457040A (en) 2009-08-05

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