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FR3112391B1 - Apparatus for determining the hemoglobin or hematocrit level of a circulating liquid - Google Patents

Apparatus for determining the hemoglobin or hematocrit level of a circulating liquid Download PDF

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Publication number
FR3112391B1
FR3112391B1 FR2007200A FR2007200A FR3112391B1 FR 3112391 B1 FR3112391 B1 FR 3112391B1 FR 2007200 A FR2007200 A FR 2007200A FR 2007200 A FR2007200 A FR 2007200A FR 3112391 B1 FR3112391 B1 FR 3112391B1
Authority
FR
France
Prior art keywords
transmitter
hemoglobin
determining
light source
hematocrit level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2007200A
Other languages
French (fr)
Other versions
FR3112391A1 (en
Inventor
Stéphane Chollet
Gaëtan Coulon
Benoît Decouture
Sylvain Picot
Patricia Forest-Villegas
Francis Gadrat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
I Sep SAS
Original Assignee
I Sep SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR2007200A priority Critical patent/FR3112391B1/en
Application filed by I Sep SAS filed Critical I Sep SAS
Priority to CN202180050925.5A priority patent/CN116324384B/en
Priority to CN202180061668.5A priority patent/CN116249893B/en
Priority to AU2021306678A priority patent/AU2021306678B2/en
Priority to US18/004,547 priority patent/US20230347036A1/en
Priority to EP21746535.0A priority patent/EP4179318B1/en
Priority to BR112023000158A priority patent/BR112023000158A2/en
Priority to ES21746535T priority patent/ES2982479T3/en
Priority to ES21746534T priority patent/ES2994328T3/en
Priority to EP21746534.3A priority patent/EP4178442B1/en
Priority to US18/004,399 priority patent/US20230280331A1/en
Priority to PCT/FR2021/051271 priority patent/WO2022008849A1/en
Priority to PCT/FR2021/051272 priority patent/WO2022008850A1/en
Priority to CA3184950A priority patent/CA3184950A1/en
Priority to BR112023000088A priority patent/BR112023000088A2/en
Publication of FR3112391A1 publication Critical patent/FR3112391A1/en
Application granted granted Critical
Publication of FR3112391B1 publication Critical patent/FR3112391B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3181Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using LEDs
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N21/3151Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using two sources of radiation of different wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3577Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • G01N2201/0627Use of several LED's for spectral resolution
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/063Illuminating optical parts
    • G01N2201/0633Directed, collimated illumination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/066Modifiable path; multiple paths in one sample

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Abrégé descriptif : L’invention concerne un appareil de détermination du taux d’hématocrite et/ou du taux d’hémoglobine d’un liquide en circulation dans une portion tubulaire (2), comprenant : deux ensembles émetteur-récepteur (10 ; 20), chaque ensemble émetteur-récepteur (10 ; 20) comprenant une source lumineuse (11 ; 21) et un capteur lumineux (12 ; 22) prévus pour être agencés de part et d’autre de la portion tubulaire (2) au niveau d’une zone de circulation du liquide pour une mesure en transmission ; la source lumineuse (11 ; 21) de chacun des deux ensembles émetteur-récepteur (10 ; 20) étant configurée pour émettre des faisceaux lumineux selon une longueur d’onde d’émission choisie pour correspondre à un point isobestique de l’hémoglobine ; chaque ensemble émetteur-récepteur (10 ; 20) comprenant en outre un système de collimation (13 ; 23) du faisceau lumineux émis depuis la source lumineuse (11 ; 21) correspondante en direction du capteur lumineux (12 ; 22) correspondant. Figure de référence : figure 6Abstract: The invention relates to an apparatus for determining the hematocrit level and/or the hemoglobin level of a liquid circulating in a tubular portion (2), comprising: two transmitter-receiver assemblies (10; 20), each transmitter-receiver assembly (10; 20) comprising a light source (11; 21) and a light sensor (12; 22) intended to be arranged on either side of the tubular portion (2) at a liquid circulation zone for a transmission measurement; the light source (11; 21) of each of the two transmitter-receiver assemblies (10; 20) being configured to emit light beams according to an emission wavelength chosen to correspond to an isosbestic point of the hemoglobin; each transmitter-receiver assembly (10; 20) further comprising a collimation system (13; 23) of the light beam emitted from the corresponding light source (11; 21) towards the corresponding light sensor (12; 22). Reference figure: figure 6

FR2007200A 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating liquid Active FR3112391B1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR2007200A FR3112391B1 (en) 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating liquid
US18/004,399 US20230280331A1 (en) 2020-07-08 2021-07-08 Device And Method For Determining The Haemoglobin Or Haematocrit Level Of A Flowing Liquid
AU2021306678A AU2021306678B2 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
US18/004,547 US20230347036A1 (en) 2020-07-08 2021-07-08 Device For Determining The Level Of Haemoglobin Or Haematocrit Of A Circulating Liquid
EP21746535.0A EP4179318B1 (en) 2020-07-08 2021-07-08 Device and method for determining the haemoglobin or haematocrit level of a flowing liquid
BR112023000158A BR112023000158A2 (en) 2020-07-08 2021-07-08 APPARATUS AND PROCESS FOR DETERMINING THE HEMOGLOBIN OR HEMATOCRIT RATE OF A FLUID IN CIRCULATION
ES21746535T ES2982479T3 (en) 2020-07-08 2021-07-08 Apparatus and method for determining the level of hemoglobin or hematocrit of a circulating fluid
ES21746534T ES2994328T3 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
CN202180050925.5A CN116324384B (en) 2020-07-08 2021-07-08 Device and method for determining the hemoglobin or hematocrit level of a flowing liquid
CN202180061668.5A CN116249893B (en) 2020-07-08 2021-07-08 Device used to measure hemoglobin levels or hematocrit levels in circulating fluids.
PCT/FR2021/051271 WO2022008849A1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
PCT/FR2021/051272 WO2022008850A1 (en) 2020-07-08 2021-07-08 Device and method for determining the haemoglobin or haematocrit level of a flowing liquid
CA3184950A CA3184950A1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid
BR112023000088A BR112023000088A2 (en) 2020-07-08 2021-07-08 APPARATUS FOR DETERMINING THE HEMOGLOBIN OR HEMATOCRIT RATE OF A FLUID IN CIRCULATION
EP21746534.3A EP4178442B1 (en) 2020-07-08 2021-07-08 Device for determining the level of haemoglobin or haematocrit of a circulating liquid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2007200A FR3112391B1 (en) 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating liquid
FR2007200 2020-07-08

Publications (2)

Publication Number Publication Date
FR3112391A1 FR3112391A1 (en) 2022-01-14
FR3112391B1 true FR3112391B1 (en) 2024-11-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
FR2007200A Active FR3112391B1 (en) 2020-07-08 2020-07-08 Apparatus for determining the hemoglobin or hematocrit level of a circulating liquid

Country Status (1)

Country Link
FR (1) FR3112391B1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5553615A (en) * 1994-01-31 1996-09-10 Minnesota Mining And Manufacturing Company Method and apparatus for noninvasive prediction of hematocrit
US5601080A (en) * 1994-12-28 1997-02-11 Coretech Medical Technologies Corporation Spectrophotometric blood analysis
US6041246A (en) * 1997-10-14 2000-03-21 Transonic Systems, Inc. Single light sensor optical probe for monitoring blood parameters and cardiovascular measurements
WO2011107102A1 (en) * 2010-03-04 2011-09-09 Unisensor A/S Flexible sample container
CA2817148C (en) * 2010-11-17 2017-07-18 Fresenius Medical Care Holdings, Inc. Sensor clip assembly for an optical monitoring system

Also Published As

Publication number Publication date
FR3112391A1 (en) 2022-01-14

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