[go: up one dir, main page]

FR3080621B1 - Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde - Google Patents

Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde Download PDF

Info

Publication number
FR3080621B1
FR3080621B1 FR1853681A FR1853681A FR3080621B1 FR 3080621 B1 FR3080621 B1 FR 3080621B1 FR 1853681 A FR1853681 A FR 1853681A FR 1853681 A FR1853681 A FR 1853681A FR 3080621 B1 FR3080621 B1 FR 3080621B1
Authority
FR
France
Prior art keywords
igg5
recombinant
gene
encoded
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1853681A
Other languages
English (en)
Other versions
FR3080621A1 (fr
Inventor
Michel Cogne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre Hospitalier Univ De Limoges
Centre National de la Recherche Scientifique CNRS
Etablissement Francais du Sang
Universite de Limoges
Centre Hospitalier Universitaire de Limoges
Original Assignee
Centre Hospitalier Univ De Limoges
Centre National de la Recherche Scientifique CNRS
Etablissement Francais du Sang
Universite de Limoges
Centre Hospitalier Universitaire de Limoges
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Hospitalier Univ De Limoges, Centre National de la Recherche Scientifique CNRS, Etablissement Francais du Sang, Universite de Limoges, Centre Hospitalier Universitaire de Limoges filed Critical Centre Hospitalier Univ De Limoges
Priority to FR1853681A priority Critical patent/FR3080621B1/fr
Priority to CN201980028507.9A priority patent/CN112262154A/zh
Priority to US17/050,403 priority patent/US20210139599A1/en
Priority to EP19725033.5A priority patent/EP3784698A1/fr
Priority to PCT/EP2019/060764 priority patent/WO2019207120A1/fr
Publication of FR3080621A1 publication Critical patent/FR3080621A1/fr
Application granted granted Critical
Publication of FR3080621B1 publication Critical patent/FR3080621B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR1853681A 2018-04-26 2018-04-26 Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde Active FR3080621B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1853681A FR3080621B1 (fr) 2018-04-26 2018-04-26 Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde
CN201980028507.9A CN112262154A (zh) 2018-04-26 2019-04-26 人类重链伪γ基因编码的新型IGG5类重组免疫球蛋白
US17/050,403 US20210139599A1 (en) 2018-04-26 2019-04-26 Recombinant immunoglobulins of a new igg5 class, encoded by the human heavy chain pseudo-gamma gene
EP19725033.5A EP3784698A1 (fr) 2018-04-26 2019-04-26 Immunoglobulines recombinées d'une nouvelle classe d'igg5, codées par le gène pseudo-gamma de chaîne lourde humaine
PCT/EP2019/060764 WO2019207120A1 (fr) 2018-04-26 2019-04-26 Immunoglobulines recombinées d'une nouvelle classe d'igg5, codées par le gène pseudo-gamma de chaîne lourde humaine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1853681A FR3080621B1 (fr) 2018-04-26 2018-04-26 Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde
FR1853681 2018-04-26

Publications (2)

Publication Number Publication Date
FR3080621A1 FR3080621A1 (fr) 2019-11-01
FR3080621B1 true FR3080621B1 (fr) 2022-12-09

Family

ID=65031194

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1853681A Active FR3080621B1 (fr) 2018-04-26 2018-04-26 Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde

Country Status (5)

Country Link
US (1) US20210139599A1 (fr)
EP (1) EP3784698A1 (fr)
CN (1) CN112262154A (fr)
FR (1) FR3080621B1 (fr)
WO (1) WO2019207120A1 (fr)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
WO1993006217A1 (fr) 1991-09-19 1993-04-01 Genentech, Inc. EXPRESSION DANS L'E. COLI DE FRAGMENTS D'ANTICORPS POSSEDANT AU MOINS UNE CYSTEINE PRESENTE SOUS FORME D'UN THIOL LIBRE, ET LEUR UTILISATION DANS LA PRODUCTION D'ANTICORPS BIFONCTIONNELS F(ab')¿2?
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5840523A (en) 1995-03-01 1998-11-24 Genetech, Inc. Methods and compositions for secretion of heterologous polypeptides
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
JP2003512821A (ja) 1999-10-04 2003-04-08 メディカゴ インコーポレイテッド 外来性遺伝子の転写調節方法
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
WO2003087324A2 (fr) * 2002-04-09 2003-10-23 Children's Hospital, Inc. Transfert de gene d'anticorps et virus recombinants adeno-associes utilises a cet effet
WO2008062904A1 (fr) * 2006-11-21 2008-05-29 Riken Procédé permettant l'expression stable de transgène
EP2281845B1 (fr) * 2008-04-25 2020-09-02 Kyowa Kirin Co., Ltd. Anticorps polyvalent stable
GB201107170D0 (en) * 2011-04-28 2011-06-15 Clark Michael Binding molecules with biased recognition
EP2900696A1 (fr) * 2012-09-25 2015-08-05 Glenmark Pharmaceuticals S.A. Purification d'immunoglobulines hétérodimères

Also Published As

Publication number Publication date
EP3784698A1 (fr) 2021-03-03
US20210139599A1 (en) 2021-05-13
FR3080621A1 (fr) 2019-11-01
CN112262154A (zh) 2021-01-22
WO2019207120A1 (fr) 2019-10-31

Similar Documents

Publication Publication Date Title
EP3827151A4 (fr) Mécanisme d'embrayage modulaire
ZA202104357B (en) Monoclonal antibodies against the beta chain region of human trbv9
IL279144A (en) Tetrahydro-1H-pyrazino[2,1-azisoindolylquinoline compounds for the treatment of immune system disease
MA54521A (fr) Dérivés d'oxopyridine substitués
IL282375A (en) 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione for suppressing and treating α-synucleinopathies, tauopathies, and other disorders
IL286696A (en) Humanized anti-claudin 18.2 chimeric antigen receptors and uses thereof
MA53857A (fr) Réacteur continu d'inactivation virale
EP3840756A4 (fr) Synthèse améliorée de la 1,4-diazaspiro[5.5]undécan-3-one
MA53875A (fr) Traitement avec des compositions d'igg hautement sialylées
EP3836801A4 (fr) Immunothérapie orale de désensibilisation à l'arachide avec dose d'entretien
MA52019A (fr) Schéma posologique de modulateur d'assemblage de capside
EP4241729A4 (fr) Attachement de prothèse dentaire
EP3793550A4 (fr) Composés 2,2'-bipyrimidinyl substitués, analogues de ceux-ci, et procédés les utilisant
EP3903723A4 (fr) Combiné d'implant dentaire
EP3989978A4 (fr) Préparation d'un lyophilisat d'annamycine préliposomique
EP4001298A4 (fr) Composition polyvalente induisant l'immunogénicité pour papillomavirus humain
FR3080621B1 (fr) Nouvelle classe d'immunoglobuline recombinante de type g : igg5, codee par le pseudo-gene gamma humain de chaine lourde
EP3964192A4 (fr) Procédé de blanchiment des dents
EP4048188C0 (fr) Système de blanchiment des dents
EP4008404A4 (fr) Récepteur d'antigène
JP1667983S (ja) 子供用椅子の保護枠
IL291640A (en) Compounds of 1,8-naphthyridin-2-one for the treatment of autoimmune disease
EP4003219C0 (fr) Irrigateur buccal à prévention du reflux
KR102090101B9 (ko) 구강 질환 예방 또는 치료용 조성물
GB201820756D0 (en) MJ's-vimana

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 2

PLSC Publication of the preliminary search report

Effective date: 20191101

PLFP Fee payment

Year of fee payment: 3

ST Notification of lapse

Effective date: 20201209

RN Application for restoration

Effective date: 20210127

FC Decision of inpi director general to approve request for restoration

Effective date: 20210205

PLFP Fee payment

Year of fee payment: 4

PLFP Fee payment

Year of fee payment: 5

PLFP Fee payment

Year of fee payment: 6

PLFP Fee payment

Year of fee payment: 7