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FR3072875B1 - Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes - Google Patents

Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes Download PDF

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Publication number
FR3072875B1
FR3072875B1 FR1760307A FR1760307A FR3072875B1 FR 3072875 B1 FR3072875 B1 FR 3072875B1 FR 1760307 A FR1760307 A FR 1760307A FR 1760307 A FR1760307 A FR 1760307A FR 3072875 B1 FR3072875 B1 FR 3072875B1
Authority
FR
France
Prior art keywords
glp
receptor agonist
polyaminoacid
composition consisting
carboxylate charges
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1760307A
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English (en)
Other versions
FR3072875A1 (fr
Inventor
Remi Soula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adocia SAS
Original Assignee
Adocia SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adocia SAS filed Critical Adocia SAS
Priority to FR1760307A priority Critical patent/FR3072875B1/fr
Priority to PCT/EP2018/079912 priority patent/WO2019086559A1/fr
Publication of FR3072875A1 publication Critical patent/FR3072875A1/fr
Application granted granted Critical
Publication of FR3072875B1 publication Critical patent/FR3072875B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

[0001] L'invention concerne une composition stable physiquement sous forme d'une solution aqueuse injectable, dont le pH est compris entre 6,0 et 8,0, comprenant au moins : a) un agoniste du récepteur du GLP-2 ou un analogue du GLP-2, ou h[Gly2]GLP-2, et b) un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes Hy, ledit co-polyaminoacide étant constitué d'unités glutamiques ou aspartiques et lesdits radicaux hydrophobes Hy.
FR1760307A 2017-10-31 2017-10-31 Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes Expired - Fee Related FR3072875B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1760307A FR3072875B1 (fr) 2017-10-31 2017-10-31 Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
PCT/EP2018/079912 WO2019086559A1 (fr) 2017-10-31 2018-10-31 Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1760307 2017-10-31
FR1760307A FR3072875B1 (fr) 2017-10-31 2017-10-31 Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes

Publications (2)

Publication Number Publication Date
FR3072875A1 FR3072875A1 (fr) 2019-05-03
FR3072875B1 true FR3072875B1 (fr) 2020-11-06

Family

ID=61521593

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1760307A Expired - Fee Related FR3072875B1 (fr) 2017-10-31 2017-10-31 Composition comprenant un agoniste du recepteur du glp-2 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes

Country Status (1)

Country Link
FR (1) FR3072875B1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9905416D0 (en) * 1999-03-09 1999-05-05 Allelix Biopharma Small molecules having GLP-2 like activity
GB9930882D0 (en) * 1999-12-30 2000-02-23 Nps Allelix Corp GLP-2 formulations
CN113730555A (zh) * 2012-01-09 2021-12-03 阿道恰公司 Ph为7且至少含pi为5.8至8.5之基础胰岛素和取代共聚(氨基酸)的可注射溶液
WO2014096440A2 (fr) * 2012-12-21 2014-06-26 Novozymes Biopharma Dk A/S Composition
FR3052071B1 (fr) * 2016-06-07 2018-09-07 Adocia Compositions sous forme d'une solution aqueuse injectable comprenant du glucagon et un co-polyaminoacide

Also Published As

Publication number Publication date
FR3072875A1 (fr) 2019-05-03

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