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FR3047012B1 - PRIMARY CELL MICROCAPSULE - Google Patents

PRIMARY CELL MICROCAPSULE Download PDF

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Publication number
FR3047012B1
FR3047012B1 FR1650638A FR1650638A FR3047012B1 FR 3047012 B1 FR3047012 B1 FR 3047012B1 FR 1650638 A FR1650638 A FR 1650638A FR 1650638 A FR1650638 A FR 1650638A FR 3047012 B1 FR3047012 B1 FR 3047012B1
Authority
FR
France
Prior art keywords
primary cell
microcapsule
cell microcapsule
present
liquid core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1650638A
Other languages
French (fr)
Other versions
FR3047012A1 (en
Inventor
Noushin Dianat
Nicolas Bremond
Jerome Bibette
Andrew Griffiths
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Ecole Superieure de Physique et Chimie Industrielles de Ville de Paris ESPCI
Original Assignee
Ecole Superieure de Physique et Chimie Industrielles de Ville de Paris ESPCI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecole Superieure de Physique et Chimie Industrielles de Ville de Paris ESPCI filed Critical Ecole Superieure de Physique et Chimie Industrielles de Ville de Paris ESPCI
Priority to FR1650638A priority Critical patent/FR3047012B1/en
Priority to PCT/FR2017/050178 priority patent/WO2017129907A1/en
Publication of FR3047012A1 publication Critical patent/FR3047012A1/en
Application granted granted Critical
Publication of FR3047012B1 publication Critical patent/FR3047012B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

La présente invention concerne une microcapsule comprenant au moins une cellule primaire de type II étant formée d'un cœur liquide et d'une enveloppe gélifiée encapsulant le cœur liquide. La présente invention concerne en outre l'utilisation de cette microcapsule pour la culture in vitro 3D, la fabrication d'organe artificiel, le criblage de composés tests.The present invention relates to a microcapsule comprising at least one type II primary cell being formed of a liquid core and a gelled envelope encapsulating the liquid core. The present invention further relates to the use of this microcapsule for 3D in vitro culture, the manufacture of artificial organs, the screening of test compounds.

FR1650638A 2016-01-26 2016-01-26 PRIMARY CELL MICROCAPSULE Expired - Fee Related FR3047012B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1650638A FR3047012B1 (en) 2016-01-26 2016-01-26 PRIMARY CELL MICROCAPSULE
PCT/FR2017/050178 WO2017129907A1 (en) 2016-01-26 2017-01-26 Microcapsule containing primary cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1650638A FR3047012B1 (en) 2016-01-26 2016-01-26 PRIMARY CELL MICROCAPSULE

Publications (2)

Publication Number Publication Date
FR3047012A1 FR3047012A1 (en) 2017-07-28
FR3047012B1 true FR3047012B1 (en) 2020-07-31

Family

ID=56008680

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1650638A Expired - Fee Related FR3047012B1 (en) 2016-01-26 2016-01-26 PRIMARY CELL MICROCAPSULE

Country Status (2)

Country Link
FR (1) FR3047012B1 (en)
WO (1) WO2017129907A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2939012B1 (en) * 2008-12-01 2015-03-27 Capsum PROCESS FOR MANUFACTURING A SERIES OF CAPSULES, AND ASSOCIATED SERIES OF CAPSULES
FR2986165B1 (en) * 2012-01-31 2015-07-24 Capsum PROCESS FOR PREPARING RIGIDIFIED CAPSULES
FR3014691B1 (en) * 2013-12-13 2016-02-05 Ets Francais Du Sang CAPSULES CONTAINING CELLS WITH HEMATOPOIETIC POTENTIALITY

Also Published As

Publication number Publication date
WO2017129907A1 (en) 2017-08-03
FR3047012A1 (en) 2017-07-28

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Year of fee payment: 2

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Effective date: 20170728

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Effective date: 20180622

Owner name: ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDU, FR

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