FR2916971A1 - Slimming kit, useful for slim the body to treat bags under the eyes, comprises substrate comprising biocellulose, and composition impregnating the substrate, comprising active slimming agent containing e.g. caffeine and its derivatives - Google Patents

Abstract

Slimming kit comprises a substrate comprising biocellulose, and a composition impregnating the substrate, comprising an active slimming agent containing caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethyltheophylline, diprophylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, combination of caffeine and silanol, natural origin compounds containing xanthic bases comprising extract of tea, coffee, guarana, cocoa, mate or cola. Slimming kit comprises a substrate comprising biocellulose, and a composition impregnating the substrate, comprising at least an active slimming agent comprising caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethyltheophylline, diprophylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, combination of caffeine and silanol, natural origin compounds containing xanthic bases comprising extract of tea, coffee, guarana, cocoa, mate or cola ( Cola nitida). Independent claims are included for: (1) a slimming treatment comprising applying the substrate comprising biocellulose and impregnated of the composition containing the active slimming agent, on the skin; and (2) a process of cosmetic treatment of bags under the eyes comprising applying the substrate containing biocellulose and the impregnated composition containing the active agent on the bags.

Description

The present invention relates to slimming compositions and sets.

  Numerous publications disclose slimming compositions, for example EP 0 493 151 or WO 02/066000. In addition, a number of articles to be arranged around the body in order to exert a slimming action have already been proposed. The patents FR 2 119 105, FR 2 051 052, FR 1 559 230 and FR 1 525 914 disclose elastic slimming bands. US Patent 4,946,453 discloses a thin Lycra Neoprene garment.

  The patent application FR 2 865 905 discloses a sportswear intended to fight against cellulite, comprising microencapsulated active substances. The microencapsulation technique is relatively complex to implement and moreover, once the assets released, the garment loses effectiveness. US Pat. No. 4,829,987 discloses a method for combating cellulite and losing weight, in which the user wraps himself before an exercise session with an elastic bandage which is impregnated with a mineral solution. Such a method is reserved for an activity in which the user may not have clothing covering the region surrounded by the bandage or may tolerate having the possible clothing wetted by the mineral solution impregnating the bandage.

  Many slimming compositions are known, for example having a draining action, that is to say reducing the retention of water in the epidermis and / or the superficial dermis, and / or acting by limiting the lipogenesis or promoting the lipolysis. There is a need to enhance the action of slimming compositions. According to one of its aspects, the invention achieves this through a slimming assembly comprising: a substrate comprising biocellulose; a composition comprising a slimming active agent impregnating the substrate. The slimming active agent is selected from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives. derivatives, etofylline, proxyphylline, ephedrine and its derivatives, combinations of caffeine and silanol, compounds of natural origin containing xanthine bases such as tea, coffee, guarana, mate extracts, cocoa or cola (Cola Nitida). Biocellulose promotes the diffusion of such a slimming active through the skin. In addition, biocellulose is relatively simple to obtain, chemically pure, does not require the use of specific chemical synthesis methods and in addition is completely biodegradable. The subject of the invention is also an assembly comprising a substrate comprising biocellulose and a composition comprising a slimming active agent, preferably one of those indicated above, this composition being packaged separately and intended to be applied to the substrate. and / or the body, before the substrate is applied thereto. The subject of the invention is also a slimming treatment method, in which a substrate comprising biocellulose and impregnated with a composition containing at least one slimming active agent, preferably one of those indicated above, is applied to the skin. . The composition can be applied to the substrate and then the thus impregnated substrate can be applied to the skin. It is also possible to apply the composition to the skin and then to apply the substrate to the skin.

  The invention also relates to a set of treatment bags under the eyes, comprising: - a substrate comprising biocellulose, - a composition impregnating the substrate, containing at least one active ingredient selected from caffeine and its derivatives, the citrate of caffeine, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, combinations of caffeine and silanol, naturally occurring compounds containing xanthine bases such as tea, coffee, guarana, cocoa, mate, cola (Cola Nitida) extracts.

  The invention also relates to a set of treatment bags under the eyes, comprising: - a substrate comprising biocellulose, and -a composition containing at least one active ingredient selected from caffeine and its derivatives, caffeine citrate, the theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine combinations and silanol, compounds of natural origin containing xanthine bases such as tea, coffee, guarana, cocoa, mate, cola (Cola Nitida) extracts, this composition being packaged separately and being intended to be applied to the substrate and / or the body. The invention further relates, in another of its aspects, to a process for the cosmetic treatment of bags under the eyes, comprising the step of applying to the bags a substrate comprising biocellulose and impregnated with a composition containing the less an active ingredient selected from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, combinations of caffeine and silanol, naturally occurring compounds containing xanthine bases such as tea, coffee, guarana, cocoa, mate, cola (Cola Nitida). In both the slimming treatment process and the pouch treatment method, the substrate may be left in place on the skin for a period of time greater than or equal to 5 minutes, for example a duration of between 5 minutes and 12 hours. , better a duration ranging from 15 minutes to 8 hours. Substrate The substrate contains biocellulose. Biocellulose is a material obtained by aerobic fermentation in a nutritious aqueous medium of bacteria of the genus Acetobacter (also called Gluconacetobacter) (Z. Gromet-Elhanan, S. Hestrin, Synthesis of cellulose by Acetobacter Xylinum, J. Bacteriol 85, 284- 292, 1963, US 5,962,277). The main species used is Acetobacter xylinum, although others may also produce biocellulose, for example Acetobacter pasteurianus.

  The culture conditions of this bacterium for producing biocellulose are well known, particularly from the publication Factors affecting the yield and properties of bacterial cellulose, A. Krystynowicz et al., J. Indus. Microbiol. Biotech. 29, 189-195, 2002. Biocellulose can be used in pure form or in a form combined with other types of fibers, for example fibers of natural origin, for example fibers derived from corn, hemp fibers , flax, cotton, jute, kenaf, raffia, ramie, paja toquilla, sisal, rush, alfalfa, phormium, coconut, wool, silk, soya, abaca, kumazasa, persimmon, kapok, burdock, cereal or bamboo. The biocellulose fibers may be free or bonded together and / or bound to other fibers.

  The biocellulose may be used as a sheet, obtained for example by compacting a culture of biocellulose fibers after rinsing them. The thickness of the sheet is for example between 50 and 4000 m. The substrate may comprise at least 10% by weight, based on the total mass of substrate, of biocellulose. The substrate may also consist entirely of biocellulose. The substrate may optionally be bonded to a support, especially a support for holding it in place on the skin. The substrate may be a sheet for example and the treatment device comprising the substrate may constitute a patch, a mask, a belt for the body or an article of clothing. FIG. 2 shows an assembly comprising a band 3 to be closed on itself around the body, having inner and outer faces 6 and 7 as well as attachment means 30 such as for example a hook and loop fastener or an adhesive fixation.

  The inner face 6 may be defined by a biocellulose substrate 8 and the outer face 7 by a support 9 which may be impermeable to the composition impregnating the biocellulose, as shown in FIG. 3. The support may optionally comprise a textile. The substrate 8 may be fixed permanently or not to the support 9, which may for example allow to replace a used substrate while retaining the support. The substrate may have received an impregnation of an adhesive, for example in the form of dots or a weft.

  The biocellulose substrate may be provided to the user already impregnated with the composition, the user having only to apply it to the region to be treated. Alternatively, the biocellulose substrate is impregnated at the time of use by pouring the active-containing composition thereon or by depositing the composition on a skin region and then applying the substrate to that skin region. The region treated with the composition may be for example a region of the arms, legs or bust, as shown in Figure 4, or neck. The bags under the eyes can still be treated. By way of illustration, FIG. 5 shows a reniform patch for the treatment of bags under the eyes. Slimming active The slimming active agent has for example a draining action and / or promoting lipolysis and / or limiting lipogenesis. Such an asset may especially have a draining action on the bags under the eyes, which can improve their appearance. The slimming active agent may be selected from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine and silanol combinations, naturally occurring compounds containing xanthine bases such as tea, coffee, guarana, mate extracts , cocoa or cola (Cola Nitida). The mtotal ratio of the slimming or pouch / msubstrate active agents may be greater than or equal to 0.001, for example from 0.001 to 0.05, where mtotal slimming or bagging agents refers to the total mass of active ingredients (s). ) slimming (s) or bag treatment and msubstrate means the mass of the substrate. The impregnating or impregnating composition may further comprise an active ingredient selected from vegetable extracts of Garcinia Cambogia, extracts of Bupleurum chinensis, extracts of climbing ivy (Hedera Helix), arnica (Arnica Montana L), Rosemary (Rosmarinus officinalis L), Marigold (Calendula officinalis), Sage (Salvia officinalis L), Ginseng (Panax ginseng), St. John's Wort (Hypericum Perforatum), Butcher's broom (Ruscus aculeatus L), Ulmaria (Filipendula ulmaria) L), orthosiphon (Orthosiphon Stamincus Benth), birch (Betula alba), cecropia and argan, ginkgo biloba extracts, horsetail extracts, escin extracts, phospholipid and proanthocyanidins of chestnut bark, cangzhu extracts, chrysanthemum indicium extracts, sapogenins such as diosgenin or hecogenin, their derivatives and natural extracts containing them, in particular Wild Yam, extracts thereof s plants of the genus Armeniacea, Atractylodis Platicodon, Sinom-menum, Pharbitidis, Flemingia, extracts of Coleus such as C.

  Forskohlii, C. blumei, C. esquirolii, C. scutellaroides, C. xanthantus and C. Barbatus, extracts of Ballot, extracts of Guioa, Davallia, Terminalia, Barringtonia, Trema, Antirobia, extracts algae or phytoplankton such as rhodysterol or Laminaria Digitata extract, skeletonema algae and diatoms, Dioscorea extracts rich in diosgenin, for example from wild yam roots.

  Other compounds The composition impregnating the biocellulose substrate may contain all the usual adjuvants used in the cosmetic and / or dermatological field, such as surfactants, polymers, oils, emollients, thickeners, preservatives, antioxidants, solvents , complexing agents, perfumes, dyestuffs, this list not being limiting. The composition impregnating the biocellulose may be in various forms, in particular in the form of an aqueous or alcoholic solution, in anhydrous form such as, for example, an oil or a balm, or O / W or W / O emulsions having for example the appearance of a cream or a milk or in the form of emulsified or limpid gels, hydroalcoholic or not, or also in particulate form (vesicles, capsules, micro and nano particles). Comparative Examples A biocellulose sheet is obtained by aerobic static fermentation of a strain of Acetobacter Xylinum (strain ATCC 23767) according to the method described in Factors affecting the yield and properties of bacterial cellulose, A. Krystynowicz et al., J. Indus. Microbiol. Biotech. 29, 189-195, 2002, incorporated herein by reference. The mass of biocellulose obtained after fermentation is rinsed with distilled water, washed with a dilute sodium hydroxide solution and then neutralized with a solution of acetic acid. After rinsing with distilled water, the mass of biocellulose is pressed to obtain a sheet about 1 mm thick.

  The biocellulose sheet is then immersed in 100 ml of an aqueous caffeine solution at 10 mg / ml for 16 hours. The cellulose sheet is then quickly wiped with absorbent paper to remove excess solution.

  A 3 cm round is cut with a punch in the thus impregnated biocellulose sheet and placed on excised human skin, dermatomed at about 500 m and maintained in survival on a Franz diffusion cell. At the same time, the caffeine solution is also placed on the skin in Franz's cell and serves as a control. The same amount of caffeine per Franz cell, 2.5 mg, is applied for biocellulose or solution alone. The caffeine concentration in the receptor phase is measured by HPLC at 6h, 12het24h. The results given in FIG. 1 are obtained. In all the times studied, a caffeine concentration in the receiving phase is observed approximately 10 times higher, when the solution is impregnated in the biocellulose sheet with respect to the solution alone. The in vitro penetration into Franz cells of the caffeine impregnated into the biocellulose was also compared to that obtained either by a commercial emulsion (PerfectSlim Gel, L'OREAL PARIS, containing 1.5% of caffeine), or by a patch. slimming (hydrogel patch based on sodium polyacrylate containing 1.5% caffeine). The following results are obtained: Biocellulose Gel PerfectSlim Hydrogel patch Amount of caffeine in the 33.79 3.25 5.07 1.79 17.21 6.40 receptor phase at 12 h (tg) Biocellulose induces in vitro a caffeine penetration higher than that obtained either by an emulsion or by a hydrogel patch Examples of sets Decongestant product, anti-pockets for the eye contour. A biocellulose patch in the form of an eye contour is impregnated in a 1: 1 mass ratio by an aqueous solution containing 0% of caffeine.The impregnated patch is put in sachet then it is sterilized by autoclaving at 121 ° C. for 20 minutes. The patch is intended to be applied for 20 minutes on the underside of the eye at the level of the pockets to obtain a decongestant effect Body product intended to exert a slimming, lipolytic and firming action.

  A 20 cm x 40 cm biocellulose strip is impregnated in a ratio of 1: 0.5 by weight of the following formula (in%): CAFEIN: 2.0000 -TRIETHANOLAMINE: 0.2200 EXTRACT OF HYDROLYZED SOY FIBERS : 1.0000 - SALICYLIC ACID: 0.1900 - ALCOHOL DENATURE: 20.0000 - WATER QSP -GLYCERIN: 3.0000 - HYDROGENATED OIL OIL: 0.6000 The impregnated biocellulose strip is intended to be applied for 30 minutes on the thighs to obtain a slimming and firming effect. The expression containing one must be understood as being synonymous with at least one, unless the opposite is specified.

Claims (23)

  1. Slimming assembly comprising: a substrate (8) comprising biocellulose, a composition impregnating the substrate, containing at least one slimming active agent chosen from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethyltheophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine and silanol combinations, of natural origin containing xanthine bases such as extracts of tea, coffee, guarana, cocoa, mate, cola (Cola Nitida).   2. Slimming assembly comprising a substrate (8) comprising biocellulose and a composition containing at least one slimming active agent, this composition being packaged separately and intended to be applied to the substrate and / or the body.   3. Set of treatment bags under the eyes, comprising: - a substrate (8) comprising biocellulose, - a composition impregnating the substrate, containing at least one active ingredient selected from caffeine and its derivatives, caffeine citrate, the theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine combinations and silanol, naturally occurring compounds containing xanthine bases such as tea, coffee, guarana, cocoa, mate, cola (Cola Nitida) extracts.   4. Set of treatment bags under the eyes, comprising biocellulose and a composition containing at least one active ingredient selected from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine and silanol combinations, naturally occurring compounds containing bases xanthines such as extracts of tea, coffee, guarana, cocoa, mate, cola (ColaNitida), this composition being packaged separately and intended to be applied to the substrate and / or the face.   5. The assembly according to claim 2, the composition containing at least one slimming active agent chosen from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine and silanol combinations, naturally occurring compounds containing xanthine bases such as tea extracts , coffee, guarana, cocoa, mate, cola (Cola Nitida).   6. An assembly according to any one of claims 1 to 3, further comprising an active ingredient selected from plant extracts of Garcinia Cambogia, extracts of Bupleurum chinensis, extracts of climbing ivy (Hedera Helix), arnica (Arnica Montana L), Rosemary (Rosmarinus officinalis L), Marigold (Calendula officinalis), Sage (Salvia officinalis L), Ginseng (Panax ginseng), St. John's Wort (Hypericum Perforatum), Butcher's broom (Ruscus aculeatus L), larch (Filipendula ulmaria L), orthosiphon (Orthosiphon Stamincus Benth), birch (Betula alba), cecropia and argan tree, ginkgo biloba extracts, horsetail extracts, escin extracts, phospholipid and proanthocyanidins of chestnut bark, extracts of cangzhu, chrysanthemum indicium extracts, sapogenins such as diosgenin or hecogenin, their derivatives and natural extracts containing them, in particular Wild Yam, plant extracts s of the genus Armeniacea, Atractylodis Platicodon, Sinom-menum, Pharbitidis, Flemingia, extracts of Coleus such as C. Forskohlii, C. blumei, C. esquirolii, C. scutellaroides, C. xanthantus and C. Barbatus, extracts of Ballote extracts of Guioa, Davallia, Terminalia, Barringtonia, Trema, Antirobia, extracts of algae or phytoplankton such as rhodysterol or Laminaria Digitata extract, skeletonema algae and diatoms, dioscorea extracts rich in diosgenin, for example from roots of wild yam.   7. An assembly according to any one of claims 1 to 6, the substrate comprising caffeine.   8. An assembly according to any one of the preceding claims, the mtotal ratio slimming assets or impregnated pouches treatment / msubstrate being greater than or equal to 0.001, wheremtotal slimming assets or bag treatment designates the total mass of active (s) ) slimming (s) and msubstrate means the mass of the impregnated substrate.   9. Assembly according to the preceding claim, the mtotal ratio slimming assets or treatment of bags / msubstrate impregnated from 0.001 to 0.05.   10. An assembly according to any one of the preceding claims, the substrate being made of biocellulose.   11. An assembly according to any one of claims 1 to 7, the substrate comprising at least 10% by weight of biocellulose.   12. An assembly according to any one of the preceding claims, the substrate (8) being in sheet form.   13. An assembly according to any one of the preceding claims, the substrate being bonded to a support (9).   14. The assembly of claim 11, the support (9) for holding the substrate in place on the skin.   15. An assembly according to any one of claims 1 to 12, the substrate being kidney-shaped.   16. A slimming treatment method, wherein is applied to the skin a substrate comprising biocellulose and impregnated with a composition containing at least one slimming active.   17. The method of claim 16, the composition containing at least one slimming active agent selected from caffeine and its derivatives, caffeine citrate, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, the diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, caffeine and silanol combinations, naturally occurring compounds containing xanthine bases such as tea extracts , coffee, guarana, cocoa, mate, cola (Cola Nitida).   18. The method of claim 16 or 17, wherein the composition is applied to the substrate, and the substrate thus impregnated is applied to the skin.   19. The method of claim 16 or 17, wherein the composition is applied to the skin and then applied to the skin substrate.   20. A method according to any one of claims 16 to 19, the substrate being applied to the body other than on the face.   21. A method of cosmetic treatment of bags under the eyes, comprising the step of applying to the bags a substrate comprising biocellulose and impregnated with a composition containing at least one active agent selected from caffeine and its derivatives, the citrate of caffeine, theophylline and its derivatives, theobromine, acefylline, aminophylline, chloroethylthéophylline, diprofylline, diniprophylline, etamiphylline and its derivatives, etofylline, proxyphylline, ephedrine and its derivatives, combinations of caffeine and silanol, naturally occurring compounds containing xanthine bases such as tea, coffee, guarana, cocoa, mate, cola (Cola Nitida) extracts.   22. Method according to any one of claims 16 to 21, the substrate being left in place on the skin for a period of between 5 minutes and 12 hours.   23. Use of a set as defined in any one of claims 1 to 15 for thinning the body or cosmetically treat bags under the eyes.