FR2994393A1 - MULTIFUNCTION DERMAL DEVICE, TRANSMITTER OR REFLECTOR FOR OUTDOOR INFRARED RADIATION, IN PARTICULAR FOR MEDICAL PURPOSES, PATCH OR ARTICLE COMPRISING SAID MULTIFUNCTION - Google Patents

Abstract

The aim of the invention is to provide medical or sanitary articles or devices made from films of polymer / ceramic composite material, which make it possible to increase the efficiency and extend the spectrum of activity of the IRLs in the prevention and control of treatment of sanitary and physiological disorders, in the improvement of the physical and / or mental performances of an individual, or in cosmetic treatments. To this end, the invention relates to a multifilette intended to be applied to the body of a living individual to emit and / or return to this body at least one far infrared radiation. This multifilette comprises at least two superimposed sheets each formed by a composite material consisting of a polymer-based matrix in which ceramic particles are dispersed capable of emitting and / or returning at least one far-infrared radiation, at least one part of these particles being preferably MnO-based particles and CoO-based particles. The invention also relates to a patch and other articles comprising the multi-layer referred to above, as well as to their manufacturing processes and their medical or other applications. cosmetics.

Description

TECHNICAL FIELD OF THE INVENTION The invention belongs to the field of medical devices emitters or reflectors of far-infrared radiation IRL, and intended for use in the field of medical devices that emit or reflect far-infrared radiation IRL, and are intended for use in the field of medical devices. be affixed or applied, directly or indirectly, to the body of a living individual, to provide the latter with beneficial health and / or cosmetic effects. It can be among others the prevention or treatment of certain pathologies eg those related to venous return or sleep disorder, improvement of sports performance, control of balance, healing, pain .

These devices may be IRL-charged ceramic polymer multifolds, body-fixable patches comprising these multifilettes, or articles such as technical textile materials carrying these multifilettes, particularly textile materials having improved comfort properties. Such a textile material finds its application particularly in the field of the manufacture of indoor or outdoor clothing, for humans or animals, household linen and other textile articles. These clothing articles are designed so that the IRL transmitter / receiver manifolds are arranged facing and / or in direct or indirect contact and / or near specific areas of the body of the individual to be treated. The invention also relates to the manufacture of these devices and the processing methods implementing them. Technological background and technical problem Infrared is generally considered to have a wavelength of between 0.76 and 1000 μm. They are classified between near infrared, average infrared and far infrared (IR), the latter corresponding to the range of wavelengths from 3 μm to 1000 μm inclusive. When irradiated with infrared, water and organic and / or high molecular weight materials may partially absorb them. IRLs whose wavelength is between 4 i.tm and 14 i.tm are particularly interesting. Indeed, this range of wavelengths promotes resonance and activation of water molecules. This is the case with water of animal or vegetable organisms. The effects induced include the following: increase the temperature of the skin and cause a sensation of heat, being absorbed at the level of the skin (epidermis and / or dermis), where the energy of the far infrared radiation is converted into heat, increase the blood flow to the skin through the dilation of the 5 capillaries, which promotes blood circulation, activate the metabolism, reduce the sensation of pain. The IRL presides over all growth and all development of life in nature. IRLs are those emitted predominantly by the human or animal body in the form of heat. The body responds to this phenomenon by dilating the blood vessels to improve circulation at all levels, which revitalizes the tissues and contributes to their repair and regeneration. Most materials emit IRLs. Certain ceramics (for example those chosen from metal oxides) may emit infrared radiation when they receive energy. In particular, metal oxide ceramics have the property of returning IRLs, especially those emitted by the human body when these ceramics are placed on the latter. The state of the art thus includes patent applications which describe articles loaded with ceramics sensitive to IRLs and used for sanitary purposes. European Patent Application EP1504824A1 discloses a polyethylene terephthalate (PET) film coated with a resin and ceramic material useful as a packaging or food protection film. This material is prepared from a paste containing the resin and a solvent, in which is mixed a far infrared emitting ceramic. After coating the PET film with the paste, to a given thickness, it is dried and then all undergoes calendering. The thickness of ceramic material is lower than that of the PET film. It is also indicated in this document that it is possible to replace the PET film with a thin fabric. In addition, this document indicates that the films obtained are useful for improving the keeping warm, the warming and the health of living beings. EP1199400A2 discloses aqueous polyurethane dispersions for textile coating. These dispersions contain 5 to 150 parts by weight of ceramic powder (preferably silicon carbide) per 100 parts by weight of polymer. The coating layers made from this composition are presented as improving the ultraviolet protection and thermal insulation. This latter property results, according to this patent application, from the combination of the effects of the ceramic powder with those of microbubbles.

The products according to these patent applications are perfectible in terms of the efficiency of the IRL (emission levels), the protection and comfort of users of articles such as clothing, coated with IRL coating EP1816254B1 discloses in particular a film of composite material comprising 30% by weight of ceramic dispersed in 70% by weight of polyurethane (polymer matrix). The ceramic used has the average composition indicated below in% by mass TiO 2: 30 to 40%; SiO2: 10 to 20%; MnO2: 10 to 20% Al2O: 10 to 20%; Fe 2 O 3: 5 to 10%; MgO: 3 to 7%; Co203: 3 to 7%; ZrO2 <5%. This film is then bonded or directly coated onto a polyamide fabric treated with a hydrophobic / oleophobic compound (e.g. Teflon) by padding. The films of polymer / ceramic composite material according to EP1816254B1, are fixed on woven fabrics, nonwoven fabrics, knitted fabrics, so as to form a textile material for the manufacture, for example, of interior and exterior garments, of various accessories. clothing, or bed linen or mattresses. EP1816254B1 does not disclose other articles or devices made from these films of polymer / ceramic composite material. The EP1816254B1 therefore leaves room for the optimization of articles or devices made from these polymer / ceramic composite material films, which make it possible to improve the efficiency and extend the spectrum of IRL activity. for the prevention and treatment of health and physiological disorders, as well as the physical and / or mental performance of an individual. OBJECTS OF THE INVENTION In this context, the invention aims to satisfy at least one of the following objectives: i) to provide medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material , said articles or devices making it possible to increase the efficiency and extend the spectrum of activity of the IRLs in the prevention and treatment of an individual's health and physiological disorders, in the improvement of the physical performances and / or of an individual or in cosmetic treatments; ii) providing medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material according to EP1816254B1, said articles or devices making it possible to increase the efficiency and to extend the spectrum of activity IRLs in the prevention and treatment of an individual's sanitary and physiological disorders, in improving the physical and / or mental performance of an individual or in cosmetic treatments; iii) providing medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material intended to be applied to the body of an individual to emit and / or return to that body at least one IRL radiation for preventive and / or therapeutic and / or cosmetic purposes and / or for the purpose of improving one or more of its physiological functions; iv) providing medical, sanitary or cosmetic articles or devices made from composite material films; polymer / ceramic satisfying at least one of the objectives (i) to (iii) above, while providing the individual with satisfactory comfort; (v) providing medical, sanitary or cosmetic articles or devices made from polymer / ceramic composite material films that meet at least one of the objectives (i) to (iv) above and that have one or more of the following characteristics: waterproofness in liquid form, permeability to water vapor, possibility of being permeable or impermeable to air; vi) providing medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material meeting at least one of the objectives (i) to (v) above and potentially enabling improvement at least one of the following functions: - venous return; - rest and sleep; analgesia and / or analgesia, in particular against periarticular and muscular pain / stiffness; lowering of the heart rate by regulation of the autonomic nervous system (ortho and para sympathetic equilibration); - scarring; - increase in muscle strength; - increase in endurance; - accelerated repairs of body cells; 30 - reduction of stress and muscle fatigue; - relief of muscle spasms; - regulation of the peripheral circulation; - regulation of the heat of an organ; - specific regulation of an organ; 35 - calming and anti-stress effect; - activation of the metabolism; - increase of the feeling of well-being; vii) providing medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material meeting at least one of the objectives (i) to (vi) above and consisting of a multifilette, a patch comprising at least one multifilette, articles or sets of articles selected from the group consisting of and ideally consisting of: clothing; the bedding ; sleeping bags, bandages, dressings; (viii) provide an industrial, economical and efficient process for the manufacture of medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material meeting at least one of the objectives (i) to (viii) ) above; (ix) provide a method of preventing and treating the health and physiological disorders of an individual; using medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material to increase efficiency and extend the spectrum of IRL activity; (x) providing a method for improving the physical and / or mental performance of an individual by using medical, sanitary or cosmetic articles or devices made from films of polymer / ceramic composite material, and for the purpose of increase efficiency and expand the spectrum of IRL activities. BRIEF DESCRIPTION OF THE INVENTION The above objectives, among others, are satisfied by the invention, which concerns first and foremost a multifilette device, here called "multifilette", intended to be applied to the body of an individual. living to emit and / or return to this body at least one far-infrared radiation, for preventive and / or therapeutic and / or cosmetic purposes and / or to improve one or more of its physiological functions, this multifilette comprising at least two superposed sheets each formed by a composite material consisting of a polymer-based matrix in which are dispersed ceramic particles capable of emitting and / or returning at least one far-infrared radiation, at least a portion of these particles being preferably, MnO2-based particles and Co203-based particles. According to an advantageous embodiment of the invention, the sheets of the multi-millet are present in a number -n- included, in increasing order of preference, between 2 and 500; 2 and 250; 2 and 150; 2 and 100; 2 and 80; 2 and 60; 2 and 50.

According to a remarkable feature of the invention, the sheets of the multifilette have thicknesses -el-1 to n- identical or different from each other, - e1-1 to n- lying between, in iam and in increasing order of preference, 0.1 and 400; 0.5 and 300; 1 and 200; 2 and 150; 3 and 100; 4 and 80; 5 and 60. Preferably, the sheets of the multifilette are assembled to each other: - preferably discontinuously via discrete zones advantageously distributed uniformly at the interface of two contiguous sheets, so that these two sheets are not attached to each other on their entire interface, and, more preferably, at least by their edges. Advantageously, at least one sheet, preferably each sheet is provided with a water vapor permeability (P), according to ASTM E96 BW at 20 ° C with 35% relative humidity, P expressed in g / m2 / 24h being in ascending order preferably between 500 to 50,000, 1,000 to 30,000; 5,000 to 12,000. According to a preferred embodiment of the invention, at least one of the sheets of the multifilette comprises particles based on carbon, preferably particles based on activated carbon and / or based on graphite. According to an advantageous particle size characteristic of the invention, the ceramic-based particles have a mean diameter D 501, measured according to the sedimentometric method such that (in iam and in a preferably increasing order): 1 <D501 <500; 1 <D501 <400; 1 <D501 <300; 1 <D501 <100; 1 <D501 <50; 2 <D501 <20; 3 <D501 <10; D501 5; The carbon-based particles have a mean diameter D 502, measured as indicated above, such that (in iam and in increasing order of preference): 1 <D 502 <500; 1 <D502 <400; 1 <D502 <300; 1 <D502 <100; 1 <D502 <50; 2 <D502 <20; <D502 <10; D 502 5; In particular, it has been found advantageous in accordance with a preferred feature of the invention to substantially increase the emissivity of the polymer / ceramic composite material, to ensure that the multi-mill comprises at least 10% by weight of of MnO 2 and at least 1% (or even at least 5%) by weight of particles based on Co 2 O 3, (% by weight relative to the total mass of the particles).

Preferably, the multifilette according to the invention comprises ceramic particles based on at least one of the following oxides: Al 2 O 3, Fe 2 O 3, TiO 2, Cr 2 O 3, SiO 2, MgO, ZrO 2, Y 2 O 3. The mixtures of several of these oxides are conceivable. According to an advantageous arrangement of the invention, the multifilette comprises at least 5%, preferably from 5% to 40%, of particles based on 5iO 2 (% by weight relative to the total mass of the particles). According to a remarkable feature of the invention, the ceramic-based particles of the multi-mill have: - either the following composition (in% by weight relative to the total mass of the particles): TiO 2 30 to 40% 5iO 2 10 to 20% MnO 2 10 to 20% Al 2 O 3 10 to 20% Fe 2 O 3 5 to 10% MgO 1 to 5% Co 2 O 3 1 to 5% ZrO 2, Cr 2 O 3, Y 2 O 3 5% each, the sum of the percentages being equal to 100%. Or the following composition (in% by weight relative to the total mass of the particles): TiO 2 from 10 to 60%, 5% from 5 to 40%, MnO 2 from 5 to 40%, Al 2 O 3 from 5 to 40%, Co203 from 1 to 10%, Fe 2 O 3 from 1 to 20%, MgO from 0 to 10%, ZrO 2, Cr 2 O 3, Y 2 O 3 5% each. The sum of the percentages being equal to 100%; The emissivity can further be substantially increased by incorporating into at least one of the sheets the carbon-based particles, preferably activated carbon and / or graphite-based particles.

The invention relates, secondly, a dermal device or patch, sticker or not. According to an advantageous characteristic of the invention, this patch comprises a support fixed on the outer face of the multifiliter, said support being provided with fixing means - preferably adhesive - on the skin of an individual and, optionally, said patch comprising in addition and preferably a protective film at least on the adhesive fixing means when they are present, and possibly on the inner face of the multifilette. The invention relates, thirdly, to an article comprising at least one patch 15 according to the invention, said article being chosen from the group comprising, or more preferably consisting of: clothing; the bedding ; sleeping bags, bandages, dressings. According to a particular embodiment of the invention, this article is a compression stocking, preferably at least a portion of the members of an individual, and more preferably still, a calf. Fourthly, the use of the above-mentioned multi-leaflet, patch and article for cosmetic purposes or for preventive and / or therapeutic and / or cosmetic medical purposes and / or for to improve one or more of its physiological functions, and in particular for at least one of the following purposes: improvement of venous return; - improvement of rest and sleep; analgesia and / or analgesia, in particular against periarticular and muscular pain / stiffness; - improving flexibility; Lowering of the heart rate, by regulation of the autonomic nervous system (ortho and para sympathetic equilibration); - improvement of healing; - increase in muscle strength; - increase in endurance; Accelerated repair of body cells; - reduction of stress and muscle fatigue; - relief of muscle spasms; - regulation of the peripheral circulation; - regulation of the heat of an organ; - specific regulation of an organ; - calming and anti-stress effect; - activation of the metabolism; - increase the feeling of well-being. The multifile (s), the patches and the articles according to the invention are used in such a way that the multifilette (s) is (are) applied to one or more zones. ) specific and determined body (s) of a living individual to emit and / or return to this body at least a far infrared radiation, to produce on this individual the aforementioned beneficial effects. The application of a multifibril to the body of an individual preferably consists in placing one of its faces facing and / or in direct or indirect contact and / or near one or more specific and determined zones. of the skin of the individual concerned. In the case where one of the faces of the multifilette is not in direct contact with the skin, but facing and / or in indirect contact and / or in the vicinity, it can be provided at least one intermediate piece, such as a textile layer, a film or a polymer foam, a dressing. Definitions Throughout this presentation, any singular denotes indifferently a singular or a plural. The definitions given hereinafter by way of example may be used for the interpretation of the present disclosure: - "X-based particles" means that the particles concerned each comprise at least 50% and up to 100% of the X. - "far infrared radiation, or IRL", is an infrared radiation whose wavelength is for example included, in jam and in increasing order preferably between 3 and 100; between 3 and 20; between 4 and 15; 4 to 14. DETAILED DESCRIPTION OF THE INVENTION The following description of details of the invention and preferred exemplary embodiments will provide a better understanding of the invention and highlight all its advantages and alternative embodiments.

Figure 1 is a schematic perspective view of a multifunctional according to the invention. FIG. 2 is a schematic representation of a patch (dressing) according to the invention integrating the multifiliter of FIG. 1.

FIGS. 3 and 4 are emissivity diagrams (E) as a function of the wavelength (λ) of the composite material constituting the multi-mill according to the invention and manufactured according to Example 1 without activated carbon (FIG. with activated charcoal (Figure 4). Figures 5A; 5B; 5C; 5D are histograms illustrating the results of 10 comparative measurements of tele-diastolic diameter (DTD). Figures 6A; 6B; 6C; 6D are histograms illustrating the results of comparative measurements of the peak of the E wave. FIGS. 7A; 7B; 7C are histograms illustrating the results of comparative measurements of the actual flow of the common femoral vein. Figures 8 & 9 are photographs of the heel of a patient before and after application of a device according to the invention to accelerate the healing of a wound. The multifilette 1 shown in FIG. 1 consists of a plurality of sheets 2 superimposed and each formed by a composite material consisting of a matrix based on polymer in which ceramic particles 20 are dispersed that are capable of emitting and / or returning at least one IRL radiation. The number n of leaflets is between 2 and 40, for example 10. The leaflets 2 are joined by their edges 3 and 4, respectively left and right, in FIG. 1. This assembly is for example made by ultrasonic welding or gluing. . The respectively anterior and posterior edges 6 in FIG. 1 are not attached to each other. The same is true of the faces facing the sheets 2, so that the latter are not secured to each other on all of their respective interfaces. According to one variant, it is conceivable for the various superimposed sheets constituting the multi-wall 1 to be assembled to one another by discontinuous fixing points distributed homogeneously or otherwise, and disposed inside and / or on the edges of the multi-wallet. 1. These sheets 2 have thicknesses -e, -1 to 30- identical or different to each other, e1-1 to 30- being between 5 and 601.1.m. Each sheet 2 is provided with a water vapor permeability P equal to 7000 g / m2 / 24h, for example. The polymer of the matrix of the leaflets 2 is preferably chosen from thermoplastic or thermosetting polymers, and even more preferably from the group comprising and ideally constituted by the following polymers: polyurethanes, acrylics, polyvinyl chlorides ( PVC), polystyrene / butadiene copolymers (SBS), natural or artificial latices (polyisoprene), polyesters, optionally halogenated polyolefins, for example fluorinated (PolyTetrafluoroethylene PTFE).

The ceramic-based particles dispersed in the matrix represent, in increasing order of preference, from 1 to 60, from 5 to 50, from 10 to 40, from 20 to 35% by weight of the composite material. In this example, the particle concentration is 30% by weight of the composite material. In this example, the ceramic-based particles of the multi-millet have the following composition (in% by weight based on the total mass of the particles). ZrO 2, Cr 2 O 3, Y 2 O 3 5% each, the sum of the percentages being equal to 100%. These ceramic-based particles have an average diameter D501, measured according to the 5 micron sedimentometric method. In addition to the ceramic-based particles, particles of activated carbon are also dispersed in the matrix of the sheets 2 in a concentration, expressed in% by weight of the composite material and given in increasing order preferably from 1 to 60, from 5 to 50, from 10 to 40, from 20 to 35, and for example in the case of 10% by weight of the composite material. These activated carbon-based particles have a mean diameter D501, measured according to the sedimentometric method of 5 microns. According to one variant, the polymer / ceramic particles (optionally activated carbon particles) composite matrix of the layers 2 is in the form of a foam. Manufacture Multifeuillet 1 In a first embodiment of the multifeuillet manufacturing process, the mother composition of the polymer of the matrix is in liquid form: dispersion of polymer or a precursor thereof in an aqueous liquid or organic, TiO 2 30 to 40% SiO 2 10 to 20% MnO 2 10 to 20% Al 2 O 3 10 to 20% Fe 2 O 3 5 to 10% MgO 1 to 5% Co 2 O 3 1 to 5% - total or partial solution of polymer or precursor of it in an organic liquid. The ceramic particles and possibly activated carbon are dispersed in this liquid mother composition.

A thin layer of this mother-compound / particle dispersion is then deposited, for example on a silicone transfer paper, according to a technique known elsewhere. To achieve this step, it is known to use a line-type coating apparatus with a squeegee fixed on a cylinder. The silicone transfer paper flows between the doctor blade and the cylinder. The parent / particle dispersion is deposited in front of the squeegee, the gap between the squeegee and the silicone transfer paper allows the deposition of the parent composition / particle dispersion and the control of the thickness of the dispersion layer. After having applied a layer of mother-compound / particle dispersion on the silicone transfer paper, the carrier liquid is removed, for example by evaporation.

In the case of removal of the carrier liquid by evaporation, the composition is heated, for example using an infrared bench, to a suitable temperature that depends on the nature of the carrier liquid. The evaporation temperature is, for example, about 60 ° C in the case of an organic phase, or about 100 ° C when the carrier liquid is an aqueous phase. Then, the polymer or its precursor is crosslinked in order to form the matrix of the composite material, increasing the temperature to about 160 ° C., preferably progressively. In doing so, the ceramic and carbon particles are homogeneously trapped in the matrix. To ensure crosslinking of the polymer or its precursor, a crosslinking agent is provided in the composition.

The thickness of the composite material film depends on the amount of mother-compound / particle dispersion deposited on the silicone transfer paper. In order to obtain a film with a thickness ranging from about 3 μm to about 60 μm dry, about 5 g / m 2 is deposited at 70 g / m 2 of the parent composition / particle dispersion. For example, for a 20 μm film, use is made between 25 g / m 2 and 30 g / m 2 of composition. The exact amount of mother / particle dispersion required for a desired film thickness varies depending on the polymer, or its precursor, the matrix, the amount of ceramic-based particles and, optionally, carbon particles in the composition. Tests within the reach of the skilled person to determine this amount.

The composite material film is then separated from the silicone transfer paper and then cut into strips which are then superposed and assembled to each other, for example by ultrasonic welding or by discontinuous bonding.

In a second embodiment of the multifilette manufacturing process, the mother composition of the polymer of the matrix is obtained by extrusion techniques. The polymer may be in the form of granules or powder for extrusion. These products are commercial products.

Briefly, to obtain the composite material film, ceramic particles, and possibly ceramic particles, are dispersed in the molten polymer. For this purpose, a sieved ceramic is used and optionally activated carbon in a very fine and homogeneous particle size. (for example D501 = D502 = 51.1m) and homogeneous. Indeed, it is preferable to use homogeneous materials in the extrusion dies. Then, the ceramic and any activated carbon are intimately mixed with the polymer, or its precursor, as solid granules. This mixture is passed through an extrusion head. The mixture based on ceramic, activated carbon and thermoplastic polymer is heated to the point of softening and melting of the thermoplastic polymer, due to the rise in temperature in the extrusion head. The mixture is advanced through the heating compartments and the extrusion head, for example by means of the worm. At the outlet of the extrusion head, the film of composite material can be obtained by calendering, blowing or stretching, according to techniques known to those skilled in the art. In both cases, the mixture is cooled until solidification to obtain a film of composite material. The film of extruded composite material is cut into strips which are then superimposed and assembled to each other, for example by ultrasonic welding or by discontinuous bonding. FIG. 2 represents a patch 8 comprising a multifiliter 1 according to the invention. This patch 8 comprises a support 9 fixed, for example by gluing, on the outer face 10 of the multifilette 1. This gluing may be provided by an adhesive film 11 applied to the inner face 12 of the support 9. In this example embodiment of the adhesive film 11 also constitutes the fastening means 13 of the support 9 on the skin of an individual, directly or indirectly (for example on at least one intermediate piece, for example another dressing without multifilette this intermediate piece being directly applied to the skin). These means 13 are placed on either side of the multifilette 1, each of these parts of the means 13 is covered with a protective film 14, 15, intended to be removed for use just before gluing the patch on the skin of the individual to be treated. Each protective film 14, 15 has, in its zone 35 at the inner end end, flaps 141 and 151, arranged opposite and above the multi-leaf 1. The support 9 can be a textile material (eg a fabric) or a fabric. polymer film.

With regard to the fabric, it may be selected from nonwoven fabrics (for example, felts), woven fabrics (warp and weft fabrics) and knitted fabrics (knitted fabrics). The fabric consists of fibers, filaments or yarns of natural and / or synthetic origin. For the record, a fiber is a filamentary element of a natural or artificial material of relatively short length. A filament is a filiform element of a natural or artificial material, of indefinite or almost indefinite length. Within the meaning of the invention, a wire will indifferently designate an elementary wire, that is to say the unitary assembly of fibers normally resulting from spinning, or a wire in the proper sense, that is to say the assembly of elementary yarns or filaments normally resulting from twisting. Among the filaments, fibers and / or yarns of natural origin, animal fibers and vegetable fibers can be distinguished. Animal fibers include silk produced by a variety of insects, including the mulberry moth, or the hairs of various mammals (sheep, goats, llamas, for example) used to make wool. Among the fibers of vegetable origin, mention may be made, for example, of cotton, linen, hemp or viscose. Mixtures of these different fibers of animal and / or vegetable origin can also be adapted. Among the synthetic or artificial fibers, filaments and threads, mention may be made, for example, of polyamides, polyesters, polyacrylics, polyethylenes, chlorofibers, polypropylenes, aramids, glasses, polyurethanes, carbons, polybenzimidazole, polyetheretherketone, phenylene polysulfide and phenolic. Mixtures of these different fibers of synthetic and / or artificial origin can also be adapted. Those skilled in the art have a wide variety of synthetic materials useful in the textile field, whose applications vary depending on the intended use. Flame-retardant additives may be added in the fabric. These flame retardant additives may be chosen from the group comprising and ideally constituted by the compounds: aramids, glasses, carbons, polybenzimidazole, polyetheretherketone, phenylene polysulfide and phenolic. With regard to the polymer film that may constitute the support, this may be a thermoplastic or thermosetting polymer which may or may not be hydrophilic. As regards the adhesive film 11, it may consist of elastomer-based adhesives with or without a tackifying agent. These elastomers may be selected from the group consisting of: acrylics, butyl rubber, vinyl acetate, natural rubber, nitrile rubber, silicone elastomer, styrene block copolymer, styrene butadiene styrene, styrene-ethylene / butylene-styrene styrene ethylene / propylene, styrene isoprene styrene, vinyl ethers, and mixtures thereof. This patch 8 shown in Figure 2, is comparable to a dressing.

According to an alternative, the patch 8 could consist of a multifilette 1 having only an adhesive film on its inner face intended to be fixed on the skin of the individual to be treated. This adhesive film is advantageously covered with a removable protective film before use.

According to another alternative, the patch 8 could consist of a multifilette 1 having no adhesive film on its inner face, which is intended to be brought into contact with the skin of the individual to be treated, directly or indirectly ( for example on at least one intermediate piece, for example another dressing without multifilette, this intermediate piece being directly applied to the skin). This contacting can be carried out in different ways. First, this patch 8 can be applied and fixed on the skin with a sparadrap® or other suitable means of attachment to the skin. Secondly, such a patch 8 may be fixed by its external face, for example by gluing, sewing or welding on a garment, a cloth, a sheet, a blanket, a sleeping bag ... Patches can have many shapes and sizes, for example, rectangular shapes with standard dimensions of 8 cm by 3 cm, 3 cm by 1 cm or 40 cm by 20 cm. It may be longer 20 strips of 20 cm wide, the length of which is adapted to the length of a bedding mattress on which the multifibre patch strips can be fixed. The dimensions of the patch can be adjusted to any other type of medium each having a specific use. Manufacture patch 8 In a first embodiment of the process for manufacturing a patch according to the invention, a film is produced for example according to the method described in the first or second embodiment described above. the process for manufacturing a multifilette I. This film is directly coated or extrusion deposited on at least one of the faces of a support, for example the support 9 of Figure 2 eg a fabric. This film directly coated on the support 9, for example a fabric, is superimposed and then assembled with several sheets 2, for example by ultrasonic welding or by discontinuous bonding. The composition of the directly coated or extrusion coated film is prepared in a manner similar to that used for the preparation of a composite material film according to the first or second embodiment described above of the manufacturing process of a multifreillet 1.

In the case where the composition of the film is a coating composition, the latter has the consistency of a paste, that is to say that it is much more viscous than the composition used to prepare a film of composite material. according to the first embodiment described above of the method of manufacturing a multifiliter 1.

After having coated the fabric with the coating composition, for example with a coating head which may be a doctor blade or a rotating frame, the composition is dried and the polymer, or its precursor, is crosslinked. to form the layer of composite material. Drying and crosslinking are carried out in a drying oven, on a conventional coating line in the technical field. Drying eliminates the carrier liquid. In doing so, the ceramic particles and possibly activated carbon are trapped in the matrix homogeneously. To ensure crosslinking of the polymer or its precursor, a crosslinking agent is provided in the coating composition.

The thickness of the layer of composite material depends on the amount of material deposited on the fabric. Since the coating composition used is more viscous, it is easier to obtain a layer of thicker composite material than in the first embodiment described above of the method of manufacturing a multi-sheet 1. The exact amount of composition required for a target thickness varies depending on the polymer, or its precursor, the matrix, the amount of ceramic in the coating composition. Tests within the reach of the skilled person to determine this amount. In the case where the composition of the film is deposited by extrusion, it may be flat die extrusion or extrusion blow molding. In this case, a liquid dispersion mother-composition / particles is used. Generally, the polymer, or its precursor, is in the molten state. The liquid dispersion is then deposited on the fabric by extrusion. The polymer is then solidified to form the matrix of the composite material. The solidification can be carried out for example by natural cooling, or by forced cooling (in particular by ventilation or by means of a cooling installation). As in the preparation of a film of composite material by extrusion according to the second embodiment described above of the manufacturing process of the multi-mill, a ceramic and screened active carbon are used to obtain a particle size distribution. very fine is regular. Then the ceramic and the activated carbon are intimately mixed with a thermoplastic polymer, or its precursor, in the form of solid granules. This mixture is passed through an extrusion head. The mixture based on ceramic, activated carbon and thermoplastic polymer is heated to the point of softening and melting of the thermoplastic polymer, due to the rise in temperature in the extrusion head. A dispersion of ceramic and activated carbon in the polymer or its precursor is obtained in the liquid state. This dispersion is advanced through the heating compartments and the extrusion head, for example using the worm. At the outlet of the extrusion head, the molten dispersion is deposited on the fabric, for example by means of a perforated cylinder. The molten dispersion is pushed through the perforations of the perforated cylinder and then flattened with a doctor blade to form a film of uniform thickness. The molten dispersion may also be deposited on the fabric 10 by means of a cylinder set on a doctor blade. The cylinder will charge molten dispersion, which is transferred onto the fabric, in the form of a film whose thickness depends on the spacing between the cylinder and the doctor blade. As mentioned above, the mixture is cooled until solidification to obtain a film of composite material. Leaflets 2 are then assembled by their edges on the film of composite material fixed on the support, for example made of fabric, for example by ultrasonic welding or by discontinuous bonding. Preferably, these sheets 2 already form a multifilette 1. Making a 1st variant of the patch 8 In this variant, a support is coated or extruded onto a support, for example a fabric, a film on these two faces, as described above in the manufacture of the patch 8. This support coated on both sides with a film of polymer / ceramic composite material and possibly activated carbon, can be assembled with one or more identical supports so as to form a variant of the patch 8, the 25 comprising a multifilette according to the invention. These supports are for example fixed to each other discontinuously, in particular by their edges, ultrasonic welding or gluing. Manufacture of a second variant of the patch 8 In this second variant, the patch 8 is obtained at the end of a process comprising a step of coating a support made of fabric or open-cell foam, based on Thermoplastic or thermosetting polymer-Al-layer, with a precursor coating composition of the composite material-Bi-layer. This fabric-composite material assembly is adhesively bonded to another layer A2 of the same nature as Al. A tricouche A1B1A2 is thus obtained. A new layer B2 for coating the precursor composition of the composite material can be applied to the layer A2 of the trilayer A1B1A2, to obtain a laminate 4 layers A1B1A2B2. It is thus possible to multiply the layers B of the composite material by interleaving between each layer B, a layer A formed by a woven or non-woven textile material or for example an open-cell foam based on thermoplastic or thermosetting polymer. The final step of obtaining this 2 "variant of the patch 8, is a step of application for example by full-surface coating or by partial surface coating of permanent-adhesive glue on the multilayer.A removable protective film before use can It is a multilayer A 1 BlA2B2 similar to that corresponding to the 2 "variant of the patch 8 described above, with the difference that it can be applied to the glue coating. that the layers BI, B2... are applied on the supports A1, A2..., not by coating but by extrusion. Manufacture of a 1st variant of patch 8 This is a multilayer A 1 BlA2B2 similar to that corresponding to the 2 "and the 3 'variant of patch 8 described above, with the difference that the layers B 1, B2 ... are applied to the supports A1, A2 ..., not only by coating or only by extrusion, but by coating or by extrusion Fabrication of a fifth variant of the patch 8 a multilayer Al B1A2B2 similar to that corresponding to the 2 ", the 3 'and the 4" variant of the patch 8 described above, with the difference that it is not planned for a final step of application, for example, by full-surface coating or by partial surface coating of permanent-adhesive glue on the multilayer, or by setting up a removable protective film before use, patch 8 according to this fifth variant can be put and maintained in direct or indirect contact with the skin of an individual to be treated, of different This contacting can be carried out in different ways. First, this patch can be applied and attached to the skin using a sparadrap® or other suitable means of attachment to the skin. In the second place, such a patch 8 can be fixed by its external face, for example by gluing, by sewing or by welding on a garment, a cloth, a blanket, a sleeping bag ... Manufacture of a variant Foam leaflets 2 It is also possible to prepare the film of composite material constituting each sheet 2, in the form of a foam. This foam can be obtained either by a physical process, a chemical process, or a combination of both. In the case of a physical process, an apparatus is used which subjects the coating composition or precursor composition of the composite material film to intense mechanical agitation. This is for example a mechanical aerator. In this case, a foam is obtained which is coated directly on the support, for example the support 9 (e.g. fabric), or deposited on a silicone transfer film. After drying and polymerization, the foam is stabilized. In a chemical process, the composition-5-mother / particle dispersion from which the film of composite material is obtained is integrated into the dispersion, foaming agents which can degrade in the form of a gas, under the effect of the temperature, in particular at the time of crosslinking of the composite material. A layer of composite foam material may have a thickness greater than the thickness of the support, for example new support which may be fabric. For example, the thickness of the layer of composite material in the form of foam can reach up to 3 mm, or even 5 mm. In an industrial production purpose, the multifilette, the patch and the other articles comprising the multifilette according to the invention can be in the form of 15 bands placed in rolls. These strips can be cut into segments that can be used for the manufacture of the multifilette, the patch, and other articles comprising the multifilette. The resulting strips or segments may be subjected to assembly operations by welding / gluing. The invention also relates to the use of the multi-leaflet, the patches and the articles, for cosmetic purposes or for purposes preventive and / or therapeutic medical and / or to improve one or more of its physiological functions. For each need (pathology, sport, balance, scarring, venous return, sleep), it is important to determine particular positions on the body of the patient, or the multifilettes and therefore the patches and articles that carry them. There are therefore accurate maps that determine the effectiveness of medical or cosmetic devices according to the invention, for each need. These positions may be for example: peripheral vascular-peripheral junctions; - Particular points of the muscle to increase the effect of contraction or relaxation; - Specific points of the tendon to increase relaxation, plyometrics, proprioception - Special points nervous (brain spinal cord, nerve plexus of the belly) in order to have effects on the heart, global relaxation, balance, ortho and parasympathetic systems, psyche. Certain maps of positioning of the multi-sheets allow the regulation of the 5 energy reserves. Other maps can have a global effect of regulation and harmonization. The invention also relates to a medical or cosmetic device comprising multifilettes and instructions for use indicating at least one positioning map of the multifeuillets on the body, corresponding to at least one medical or cosmetic treatment. The invention will now be illustrated by the following examples. EXAMPLES Example 1 - Manufacture of a multi-sheet without active carbon particles A composite material film was prepared from the parent composition dispersion of the following ceramic particle polymer (% by weight): 100 parts by weight of aliphatic ether-hydrophilic ester polyurethane dissolved in the organic liquid phase, 30% by weight; Organic liquid phase: 10 parts of toluol and 10 parts of isopropyl alcohol 2.5 parts by weight of crosslinking agent: polyisocyanate ceramic particles (TABLE 1), dispersed in the composition: 7.0 parts TABLE 1 Composition per cent average mass of a far infrared emitting ceramic Oxide% by mass TiO2 30 to 40% SiO2 10 to 20% MnO2 10 to 20% Al203 10 to 20% Fe203 5 to 10% MgO 3 to 7% Co203 3 to 7% Zr02 5% The composition based on polyurethane and ceramic is deposited on a silicone transfer paper. Then, it is dried at a temperature of about 60 ° C before being cured (or polymerized) at a temperature of about 160 ° C. A polyurethane film is obtained comprising the dispersed ceramic. Film 5 contains 30% by weight of ceramic and 70% by weight of polyurethane, which constitutes the polymer matrix of the film. The composite material film thus obtained is separated from the silicone transfer paper and is wound on a cardboard tube. The roll thus obtained is cut diametrically into sections. The sections of composite material film are then positioned / fixed vertically one above the other and parallel to each other. The number of roller sections thus positioned defines the number of layers that make up the composite film multifilette. In this example, 10 roll sections are used, which makes it possible to obtain a multi-layer of 10 layers. These 10 roll sections are unwound simultaneously. The strips from these sequences are superimposed and assembled to each other, for example by ultrasonic welding. The multifeuillet thus produced is then wound from which multi-mill segments can be cut. EXAMPLE 2 Manufacture of a Multi-Cylinder with Activated Carbon Part 20 Example 1 is reproduced by adding 5% of activated carbon particles marketed under the brand activated carbon by the company CHEMVIRON CARBON, in the polymer matrix of the film forming each sheet. EXAMPLE 3 Measurement of the IRL Emissivity of the Multifilets of Examples 1 and 2 For the quality of the composite material, in terms of the emission of far infrared rays, emissivity diagrams as shown in FIGS. the multifilettes of Examples 1 and 2. This measurement is carried out using a spectrometer in accordance with a conventional methodology such as that implemented by the "Department of Fisica - Universita di Pisa" Largo B. Pontecorvo, 3 FIG. 3 shows the curve of the emissivity% (E) as a function of the wavelength (λ), obtained for the multifreillet 1 of example 1 in which the film posite contains only the ceramic. This material has an emissivity which increases by 83% for a wavelength of 4 μm to reach a maximum of the order of 90-93% from 10 to 201 μm.

FIG. 4 shows the curve of the emissivity% (E) as a function of the wavelength (λ) obtained for the multi-sheet 1 of example 1 in which the composite film contains the ceramic and the activated carbon. This material has an emissivity which increases by 85% for a wavelength of 4 μm to reach a maximum of about 96-98% of 10 to 20 μm. The beneficial effect of the activated carbon in terms of increasing the IRL emissivity is clear from the comparison of FIGS. 3 and 4. Example 4 - Fabrication of a patch (dressing) of the type shown in FIG. implement a roll of fabric (support 9) elastic lycrae cotton. This fabric is coated using a conventional coating line with a viscous paste of a precursor elastomer (layer 11) consisting of acrylic ACRONAL V 215 from BASF. The elastomer paste coating is dried and the elastomer-coated fabric is rolled onto a roll of total width equal to 1.55 m. This roll of elastic fabric coated with an elastomer is then cut into thirty four sections of roll each having a width equal to 4.5 cm. The multifilette is first produced from composite material film of a total width of 1.55 m and then cut diametrically into 10 sections of roll each having a width equal to 15 cm. The multi-sheet is manufactured in a second step from these ten sections of roll. A set of 10 pieces of roll of composite material film? overlapping and parallel is cut longitudinally into four strips of 3.5 cm and simultaneously ultrasonically welded by their longitudinal edges, as described in Example 1. The embodiment of the dressings is done on a machine well known to man business. On one side is a rolled roll of elastomer coated fabric forming the adhesive film 11 as obtained above and on the other side a roll of composite material film multifilette as obtained above, as well as two rolls of removable polyethylene protective film before use. The roll of fabric coated with elastomer forming the adhesive film 11 is then unrolled on the machine, it is unwound / first place in the center the composite material film multifilette and then in a second time the two removable protective films before are rolled / laid across the full width and edge to edge with the roll of elastomeric coated fabric forming the adhesive film 11. One of the two removable protective films before use overlaps the other removable protective film before use in order to be able to remove the protective films removable before use before sticking the dressing on the skin. The dressing roll consisting of a first portion of elastomeric coated fabric forming the adhesive film 11, a second portion of the composite material film multifilament 5 centered on the elastomeric coated fabric forming the adhesive film 11 and a third part of the two removable protective films before use is then calendered between two cylinders to adhere the composite film multifilette and the two removable protective films before use. The last step is to cut the dressing roll continuously using a punch 10 formed of cutting blades fixed on a rotating cylinder. The dressings thus cut are packaged in boxes. Example 5 - Medical Use of Patches (Dressings) Manufactured in Example 4 Clinical Tests 1. Measurement of venous return. The protocol used is as follows: Protocol Evaluation of venous return by a central cardiac index at rest, during exercise and during post-exercise recovery in 15 healthy subjects successively carrying 20 different compression stockings between the ankle and the knee. The compression stockings give sufficient elasticity to compress the leg, thus replacing the deficiency of the walls of the veins and thus preventing the dilation of the veins and facilitating the venous return. In France, the pressure expressed in Pascal hectoliters (hPa) or millimeter mercury (mmHg), exerted by a compression stocking at the ankle, is measured according to the AFNOR G130 102B standard. The prescribed pressure varies according to the severity of the pathology. and is divided into 4 classes of compression: from the lowest class 1 to the highest class 4. 30 - class 1: 10 to 15 mm Hg - class 2: 15 to 20 mm Hg - class 3: 20 to 36 mm Hg - class 4:> to 36 mm Hg 35 (1.33 mm Hg = 1 hPa) Compression exercises degressively on the leg. Maximum at the ankle, it gradually decreases back to the thigh.

The stockings used are the following: - 6 pairs of stockings made according to the AFNOR G130 102B compression standard, with 4 levels of compression (HC, class 1, 2, 3, 4) whose compression levels are as follows: class 0 out of compression HC (control), class 1 (minimal compression), class 2 (compression medium), class 3 (strong compression) and class 4 (very large compression) - 2 pairs of low compression (class 0 without compression HC) low compression class 0 are constructed as follows: Bottom without compression HC The textile support used for the realization of these stockings is a mesh polyester fiber and lycra.

Low compression green HC green The textile support used for the realization of these stockings is a mesh polyester fiber and lycra. Patches according to Example 4 (green stockings) (1 to 1/3 upper calf, 1 upper anterointerne leg, 1 lower antero inner side of the leg, 1 outer anterolateral surface on the muscular body of the anterior tibialis) , were placed on these stockings by sewing Evaluations made: - at standing rest - at rest sitting on a Kettler X3 ergometer - during a submaximum exercise (50 Watts) - during post exercise recovery (between 30s and 2min after stopping 7) Experimental situations: - Without socks - With 5 socks with 5 levels of compression from 0 to 4 - With low green patches Indices measured by cardiac and vascular ultrasound-Doppler at rest, sitting, exercise and during recovery -> Tele-diastolic diameter (DTD) that reflects the overall filling of the heart -> Peak of the E-wave: reflects the early filling of the left ventricle 5 -> Actual flow of the femoral vein common Femoral flow = surfacevein * Vit avg (femoral venous flow) The results are shown in: Figures SA; 5B; 5C; 5D: Tele-diastolic diameter (DTD) FIGS. 6A; 6B; 6C; 6D: E wave peak FIGS. 7A; 7B; 7C: Actual flow rate of the common femoral vein The legend of the colors of the rectangles of the histograms of the figures is as follows: (white): control without bottom: class 0 out of compression HC (control) 15: class 1: class 2: class 3: class 4: low *, ie low comprising the patches according to the invention These figures show: FIGS. 5B; SC; 5D: show a similar tele-diastolic diameter (DTD) for the class 1 to 4 lows and the lows *, under the 4 experimental conditions whatever the situations studied. A trend towards DTD improvement for class 1 to 4 lows and lows, in parallel with compression level, at rest and exercise - Figs. 6A; 6B; 6C; 6D: show an improvement of the peak E in parallel with the increase of the level of compression whatever the experimental conditions. The stockings are at least as good as the class 3 or 4 compression stockings. FIGS. 7A; 7B; 7C show an improvement in the femoral flow rate in parallel with the increase in the level of compression whatever the experimental conditions. The stockings comprising the patches according to the invention have a femoral flow rate of 19% relative to the wearer without compression stockings and the compression stockings of class 3, + 22% femoral flow rate relative to the wearer without compression stockings.

The lows * comprising the patches according to the invention have a favorable effect with regard to venous return, especially in unfavorable positions for venous return (standing position and especially post-exercise) on the early filling rates of the left ventricle (strongly dependent index). preload conditions and venous return). 2. Measurement of rest and sleep. The protocol used is as follows: Application of patches of Example 4 glued on different points of the body 24/24 for a week, except the points around the skull that are placed about an hour before falling asleep and removed on waking. 30 people between the ages of 22 and 67 complaining of problems falling asleep, night awakenings, difficulty falling asleep or recurring nightmares. None are affected by sleep apnea.

The patches are deposited on the following points: - Pose of a patch: on the temples - Pose of a patch: between the two eyes - Pose of a patch: back of the head on the occiput Choice between these points: 20 - Pose of a patch: On the sternum (lower third) - Pose of a patch: Under the feet - Pose of a patch: between vertebrae T8 and T9 People are questioned about the conditions of their sleep The results obtained are as follows: Improvement of rest and sleep. In more than 75% of cases of various insomnia (21 of the thirty people tested) there is a marked improvement ranging from falling asleep to non-awakening following the laying of patches on the aforementioned places. 3. Heart rate measurement. The protocol used is as follows: The measurements are made from an ear sensor, connected to a computer with the Heartmath software (Freeze Framer). The patients are lying down, the sensor on the right ear. They are asked to relax, and Heartmath (Freeze Framer) cardiac coherence software is observed if people are able to truly relax, ie to balance the heartbeat, to create a wave. regular oscillating between an active orthosympathetic phase and an active parasympathetic phase. The orthosympathetic part is ergotropic, that is to say, it assumes the expenditure of energy. The parasympathetic part is toohotrope, that is to say animator of metabolic functions, restorers of energy. There exists therefore between the two parts, a variable equilibrium according to the physical or psychological circumstances of existence. The severe disturbance of this balance is responsible for neuro-vegetative disorders in the sense of hyper-sympathicotonia or hyper-parasympathicotonia (hyper-vagotonia).

Once this phase of 10 minutes of measurement passed, we apply patches of Example 4 on the following points: - A sternal point located between the nipples, - At three centimeters above the navel - Between the two eyes - Between the vertebrae C7 and Ti Once these bandages deposited, one looks at whether the curve evolves towards more coherence between the ortho and parasympathetic phases.

The results obtained are as follows: Drop in heart rate by approximately 5% after patches are applied and better regulation of the amplitudes between the ortho and parasympathetic phases. 4. Healing study The protocol used is as follows: 17 people injured due to accidents with life and having an open wound have either received stitches for their wound or have been treated with bandages and adhesives healing healing . In all cases, once the wounds are protected by conventional dressings, a patch completely covering the conventional dressing is applied throughout the healing period. Ex: Heel notched 3 mm deep. Wound covered with a healing bandage type compeede, so that the athlete can continue to run, itself covered by a patch according to Example 4 for 12 days. In all cases, there was no observed worsening (pus, granulocyte, wound degeneration). All wounds healed faster than the average is between 12 and 19 days depending on the case. All wounds were properly closed and none had adhesions two months later.

The photographs of FIGS. 5 & 6 show the very positive effect of the patch according to the invention on the rate of healing of the cut in the heel. 5. Study of flexibility.

The protocol used is as follows: Test on the flexibility Panel of 40 patients (20 men / 20 women) aged 18 to 70 years in underwear, in a room at room temperature (21 degrees Celsius). Single operator. This test consists in measuring the hand-ground distance by anterior flexion of the trunk. 5 patches according to Example 4 were applied directly to the following points of the body of patients: - Pose a patch below the vertebra T1 - Pose a patch between vertebrae T8 and T9 - Laying a patch between vertebrae T12 and Li - Pose of a patch on the anterior aspect of the sternum (1/3 inferior) - Pose of a patch on the lumbosacral hinge The results obtained are as follows: Improvement of the flexibility in 80% of the Patients tested, with 2 to 5 cm increase in hand-to-ground distance.

Claims (10)

REVENDICATIONS1. Multifilette intended to be applied to the body of a living individual to emit and / or return to this body at least one far infrared radiation for preventive and / or therapeutic and / or cosmetic purposes and / or to improve one or more of its physiological functions, this multifilette comprising at least two superimposed leaflets and each formed by a composite material consisting of a polymer-based matrix in which ceramic particles are dispersed capable of emitting and / or returning to the 10 less far-infrared radiation, at least a portion of these particles being preferably MnO2-based particles and Co203-based particles, Multifeed according to claim 1, wherein the leaflets are present in a number ranging from -in, preferably in increasing order, between 2 and 15,500; 2 and 250; 2 and 150; 2 and 100; 2 and 80; 2 and 60; 2 and 50. 3. Multifeed according to claim 1 or 2, wherein the sheets have thicknesses -ei.1 to n- identical or different from each other, -ei.i to n- being between, in i.tm and in ascending order. preferably, 0.1 and 400; 0.5 and 300; 1 and 200; 2 and 150; 3 and 100; 4 and 80; 5 and 60. 4. Multifeed according to at least one of the preceding claims, wherein the sheets are assembled to each other: - preferably discontinuously via discrete zones 25 advantageously distributed uniformly at the interface of two sheets contiguous, so that these two sheets are not fixed to each other on their entire interface, and, more preferably, at least by their edges. 30 5. Multifeed according to at least one of the preceding claims, wherein at least one sheet, preferably each sheet has a permeability to water vapor (P) according to ASTM E96 BW at 20 ° C with 35% relative humidity, P expressed in g / m2 / 24h being in ascending order preferably between 500 to 50,000, 1,000 to 30,000; 5,000 to 12,000. 35.3 0 6. Multifeed according to at least one of the preceding claims, wherein at least one of the sheets comprises particles based on carbon, preferably particles based on activated carbon and / or based on graphite. 7. Patch comprising at least one multifilette according to at least one of the preceding claims. 8. The patch of claim 7 comprising a support fixed on the outer face of the multifilette, said support being provided with fixing means - preferably adhesive 10 on the skin of an individual and, optionally, said patch further comprising and preferably a protective film at least on the adhesive fixing means when they are present, and possibly on the internal face of the multifilette. An article comprising at least one patch according to claim 7, said article being selected from the group consisting of, or more preferably consisting of: clothing - preferably a compression stocking; the bedding ; sleeping bags, bandages, dressings. 10. A medical or cosmetic device comprising multifilets according to at least one of claims 1 to 6 and a user guide indicating at least one positioning map multifeuillets on the body, corresponding to at least one medical or cosmetic treatment.