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FR2969999B1 - CONJUGATE, PROCESS FOR PREPARING THE SAME AND USES THEREOF - Google Patents

CONJUGATE, PROCESS FOR PREPARING THE SAME AND USES THEREOF

Info

Publication number
FR2969999B1
FR2969999B1 FR1150016A FR1150016A FR2969999B1 FR 2969999 B1 FR2969999 B1 FR 2969999B1 FR 1150016 A FR1150016 A FR 1150016A FR 1150016 A FR1150016 A FR 1150016A FR 2969999 B1 FR2969999 B1 FR 2969999B1
Authority
FR
France
Prior art keywords
conjugate
preparing
same
carbon atoms
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1150016A
Other languages
French (fr)
Other versions
FR2969999A1 (en
Inventor
Mohamed Anis Alouini
Thomas Berthelot
Rubio Sandra Albenque
Gerard Deleris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR1150016A priority Critical patent/FR2969999B1/en
Priority to PCT/EP2011/074234 priority patent/WO2012093064A1/en
Priority to EP11802452.0A priority patent/EP2661469A1/en
Publication of FR2969999A1 publication Critical patent/FR2969999A1/en
Application granted granted Critical
Publication of FR2969999B1 publication Critical patent/FR2969999B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/40—Hydrazines having nitrogen atoms of hydrazine groups being quaternised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/12—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms
    • C07C243/16—Hydrazines having nitrogen atoms of hydrazine groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to a conjugate of the formula A-R1-N (H) -N (CH2-C (=O) -R2-B) 2, in which A is a functional entity, B is a targeting entity, and R1 and R2 are identical or different and each represent a bond or a group of bonds including from 1 to 40 carbon atoms, in particular 1 to 30 carbon atoms. The present invention also relates to a method for preparing such a conjugate, and to the use thereof in medicine or diagnostics.
FR1150016A 2011-01-03 2011-01-03 CONJUGATE, PROCESS FOR PREPARING THE SAME AND USES THEREOF Expired - Fee Related FR2969999B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR1150016A FR2969999B1 (en) 2011-01-03 2011-01-03 CONJUGATE, PROCESS FOR PREPARING THE SAME AND USES THEREOF
PCT/EP2011/074234 WO2012093064A1 (en) 2011-01-03 2011-12-29 Conjugate, method for preparing same and uses thereof
EP11802452.0A EP2661469A1 (en) 2011-01-03 2011-12-29 Conjugate, method for preparing same and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1150016A FR2969999B1 (en) 2011-01-03 2011-01-03 CONJUGATE, PROCESS FOR PREPARING THE SAME AND USES THEREOF

Publications (2)

Publication Number Publication Date
FR2969999A1 FR2969999A1 (en) 2012-07-06
FR2969999B1 true FR2969999B1 (en) 2013-02-08

Family

ID=44543936

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1150016A Expired - Fee Related FR2969999B1 (en) 2011-01-03 2011-01-03 CONJUGATE, PROCESS FOR PREPARING THE SAME AND USES THEREOF

Country Status (3)

Country Link
EP (1) EP2661469A1 (en)
FR (1) FR2969999B1 (en)
WO (1) WO2012093064A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5367080A (en) * 1990-11-08 1994-11-22 Sterling Winthrop Inc. Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
FR2814744B1 (en) 2000-10-04 2002-11-29 Commissariat Energie Atomique CYCLOPEPTIDES, THEIR PREPARATION PROCESS AND THEIR USE AS ANGIOGENESIS INHIBITOR OR ACTIVATOR
EP1221465A1 (en) * 2001-01-03 2002-07-10 Innosense S.r.l. Symmetric, monofunctionalised polymethine dyes labelling reagents

Also Published As

Publication number Publication date
FR2969999A1 (en) 2012-07-06
EP2661469A1 (en) 2013-11-13
WO2012093064A1 (en) 2012-07-12

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Effective date: 20180928