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FR2959668A1 - Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs - Google Patents

Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs Download PDF

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Publication number
FR2959668A1
FR2959668A1 FR1053504A FR1053504A FR2959668A1 FR 2959668 A1 FR2959668 A1 FR 2959668A1 FR 1053504 A FR1053504 A FR 1053504A FR 1053504 A FR1053504 A FR 1053504A FR 2959668 A1 FR2959668 A1 FR 2959668A1
Authority
FR
France
Prior art keywords
acid
somatostatin
sarcoma
pancreas
melanoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR1053504A
Other languages
English (en)
Other versions
FR2959668B1 (fr
Inventor
Laurent Schwartz
Adeline Guais-Vergne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOREBUS
Original Assignee
BIOREBUS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOREBUS filed Critical BIOREBUS
Priority to FR1053504A priority Critical patent/FR2959668B1/fr
Priority to PCT/FR2011/051025 priority patent/WO2011138565A1/fr
Publication of FR2959668A1 publication Critical patent/FR2959668A1/fr
Application granted granted Critical
Publication of FR2959668B1 publication Critical patent/FR2959668B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Association pharmaceutique contenant l'acide lipoïque, l'acide hydroxycitrique et un analogue de la somatostatine à titre de principes actifs. La présente invention a pour objet une nouvelle association pharmaceutique et son utilisation en tant que composition qu'antitumorale. Selon l'invention, cette association comprend, à titre de principes actifs : - l'acide lipoïque ou l'un de ses sels pharmaceutiquement acceptables ; - l'acide hydroxycitrique ou l'un de ses sels pharmaceutiquement acceptables ; et - la somatostatine ou un de ses analogues ou l'un de leurs sels pharmaceutiquement acceptables.
FR1053504A 2010-05-05 2010-05-05 Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs Expired - Fee Related FR2959668B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1053504A FR2959668B1 (fr) 2010-05-05 2010-05-05 Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs
PCT/FR2011/051025 WO2011138565A1 (fr) 2010-05-05 2011-05-05 Association pharmaceutique contenant l'acide lipoïque, l'acide hydroxycitrique et une somatostatine a titre de principes actifs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1053504A FR2959668B1 (fr) 2010-05-05 2010-05-05 Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs

Publications (2)

Publication Number Publication Date
FR2959668A1 true FR2959668A1 (fr) 2011-11-11
FR2959668B1 FR2959668B1 (fr) 2012-07-13

Family

ID=42735757

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1053504A Expired - Fee Related FR2959668B1 (fr) 2010-05-05 2010-05-05 Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs

Country Status (1)

Country Link
FR (1) FR2959668B1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024734A1 (fr) * 1998-10-26 2000-05-04 The Research Foundation Of State University Of New York Derives d'acide lipoique et utilisation de ces derives pour le traitement de maladies
WO2000048594A1 (fr) * 1999-02-16 2000-08-24 The Center For The Improvement Of Human Functioning International, Inc. Utilisation d'une combinaison d'acide lipoique et d'acide ascorbique afin de traiter le cancer
WO2000061143A1 (fr) * 1999-04-09 2000-10-19 Antibioticos S.P.A. Utilisation d'acide lipoique alpha dans le traitement antimetastatique
WO2004100885A2 (fr) * 2003-05-09 2004-11-25 The Trustees Of The University Of Pennsylvania Compositions et methodes de traitement anticancereux
WO2009008461A1 (fr) * 2007-07-10 2009-01-15 Griffin Biotech, Ltd. Composition pharmaceutique pour une maladie provoquée par une prolifération de cellule sensible aux hormones sexuelles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024734A1 (fr) * 1998-10-26 2000-05-04 The Research Foundation Of State University Of New York Derives d'acide lipoique et utilisation de ces derives pour le traitement de maladies
WO2000048594A1 (fr) * 1999-02-16 2000-08-24 The Center For The Improvement Of Human Functioning International, Inc. Utilisation d'une combinaison d'acide lipoique et d'acide ascorbique afin de traiter le cancer
WO2000061143A1 (fr) * 1999-04-09 2000-10-19 Antibioticos S.P.A. Utilisation d'acide lipoique alpha dans le traitement antimetastatique
WO2004100885A2 (fr) * 2003-05-09 2004-11-25 The Trustees Of The University Of Pennsylvania Compositions et methodes de traitement anticancereux
WO2009008461A1 (fr) * 2007-07-10 2009-01-15 Griffin Biotech, Ltd. Composition pharmaceutique pour une maladie provoquée par une prolifération de cellule sensible aux hormones sexuelles

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200908, Derwent World Patents Index; AN 2009-E00861, XP002602219 *
SCHWARTZ LAURENT ET AL: "A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: Preliminary results", ONCOLOGY REPORTS, vol. 23, no. 5, 31 March 2010 (2010-03-31), pages 1407 - 1416, XP009139111, ISSN: 1021-335X *
WOOD A J J: "Drug therapy", NEW ENGLAND JOURNAL OF MEDICINE, THE, MASSACHUSETTS MEDICAL SOCIETY, WALTHAM, MA, US, vol. 334, no. 4, 1 January 1996 (1996-01-01), pages 246 - 254, XP002522071, ISSN: 0028-4793 *

Also Published As

Publication number Publication date
FR2959668B1 (fr) 2012-07-13

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FR2959668A1 (fr) Association pharmaceutique contenant l'acide lipoique, l'acide hydroxycitrique et une somatostatine a titre de principes actifs

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Effective date: 20140131