[go: up one dir, main page]

FR2953832B1 - Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne - Google Patents

Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne

Info

Publication number
FR2953832B1
FR2953832B1 FR0958846A FR0958846A FR2953832B1 FR 2953832 B1 FR2953832 B1 FR 2953832B1 FR 0958846 A FR0958846 A FR 0958846A FR 0958846 A FR0958846 A FR 0958846A FR 2953832 B1 FR2953832 B1 FR 2953832B1
Authority
FR
France
Prior art keywords
acne
cosmetics
prevention
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0958846A
Other languages
English (en)
Other versions
FR2953832A1 (fr
Inventor
Peter Claire Bouix
Jean Claude Pascal
Nicolas Rodeville
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Galderma Research and Development SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0958846A priority Critical patent/FR2953832B1/fr
Application filed by Galderma Research and Development SNC filed Critical Galderma Research and Development SNC
Priority to RU2012128869/04A priority patent/RU2588492C2/ru
Priority to JP2012542568A priority patent/JP5696159B2/ja
Priority to PT107909459T priority patent/PT2509944E/pt
Priority to HRP20140793AT priority patent/HRP20140793T1/hr
Priority to KR1020127017791A priority patent/KR101593263B1/ko
Priority to PCT/EP2010/069418 priority patent/WO2011070170A1/fr
Priority to SI201030732T priority patent/SI2509944T1/sl
Priority to DK10790945.9T priority patent/DK2509944T3/da
Priority to US13/514,579 priority patent/US9102607B2/en
Priority to BR112012013538-4A priority patent/BR112012013538B1/pt
Priority to CA2782948A priority patent/CA2782948C/fr
Priority to MX2012006217A priority patent/MX2012006217A/es
Priority to ES10790945.9T priority patent/ES2491640T3/es
Priority to AU2010329840A priority patent/AU2010329840B2/en
Priority to PL10790945T priority patent/PL2509944T3/pl
Priority to CN201080063361.0A priority patent/CN102741225B/zh
Priority to RS20140424A priority patent/RS53463B/sr
Priority to EP10790945.9A priority patent/EP2509944B1/fr
Publication of FR2953832A1 publication Critical patent/FR2953832A1/fr
Application granted granted Critical
Publication of FR2953832B1 publication Critical patent/FR2953832B1/fr
Priority to CY20141100693T priority patent/CY1115510T1/el
Priority to SM201400140T priority patent/SMT201400140B/xx
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C409/00—Peroxy compounds
    • C07C409/32—Peroxy compounds the —O—O— group being bound between two >C=O groups
    • C07C409/34—Peroxy compounds the —O—O— group being bound between two >C=O groups both belonging to carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/38—Percompounds, e.g. peracids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C409/00—Peroxy compounds
    • C07C409/40—Peroxy compounds containing nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0958846A 2009-12-10 2009-12-10 Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne Expired - Fee Related FR2953832B1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR0958846A FR2953832B1 (fr) 2009-12-10 2009-12-10 Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne
ES10790945.9T ES2491640T3 (es) 2009-12-10 2010-12-10 Nuevos derivados de peróxido, su procedimiento de preparación y su uso en medicina humana y en cosméticos para el tratamiento o la prevención del acné
PT107909459T PT2509944E (pt) 2009-12-10 2010-12-10 Novos derivados do peróxido, seus processos de preparação e sua utilização em medicina humana e nos cosméticos para tratamento ou prevenção da acne
HRP20140793AT HRP20140793T1 (hr) 2009-12-10 2010-12-10 Novi peroksidni derivati, postupak njihovog dobivanja i njihova upotreba u medicini i kozmetici radi lijeäśenja ili sprjeäśavanja akni
KR1020127017791A KR101593263B1 (ko) 2009-12-10 2010-12-10 신규한 퍼옥시드 유도체, 그의 제조 방법 및 여드름의 치료 또는 예방용 화장품 및 인간 의약에 있어서의 그의 용도
PCT/EP2010/069418 WO2011070170A1 (fr) 2009-12-10 2010-12-10 Nouveaux dérivés de peroxyde, leur procédé de préparation et leur utilisation en médecine humaine et dans des cosmétiques pour le traitement ou la prévention de l'acné
SI201030732T SI2509944T1 (sl) 2009-12-10 2010-12-10 Novi derivati peroksida, postopek za pripravo le-teh ter njih uporaba v humani medicini in v kozmetiki za zdravljenje in preprečevanje aken
DK10790945.9T DK2509944T3 (da) 2009-12-10 2010-12-10 Nye peroxidderivater, fremgangsmåde til fremstilling deraf og anvendelse deraf i menneskelig medicin og i kosmetik til behandling eller forebyggelse af acne
US13/514,579 US9102607B2 (en) 2009-12-10 2010-12-10 Peroxide derivatives, their process of preparation and their use in human medicine and in cosmetics for the treatment or prevention of acne
JP2012542568A JP5696159B2 (ja) 2009-12-10 2010-12-10 新規の過酸化物誘導体、その調製方法、ならびにざ瘡の治療または予防のためのヒト医薬品および化粧品へのその使用
RU2012128869/04A RU2588492C2 (ru) 2009-12-10 2010-12-10 Новые производные пероксида, способ их получения и их применение в медицине и косметике для лечения или профилактики угрей у человека
MX2012006217A MX2012006217A (es) 2009-12-10 2010-12-10 Derivados de peroxido nuevos, su proceso de preparacion y su uso en medicina humana y en cosmeticos para el tratamiento o prevencion de acne.
PL10790945T PL2509944T3 (pl) 2009-12-10 2010-12-10 Nowe pochodne nadtlenkowe, sposób ich wytwarzania i ich zastosowanie w medycynie ludzkiej i w kosmetykach do leczenia lub zapobiegania trądzikowi
CA2782948A CA2782948C (fr) 2009-12-10 2010-12-10 Nouveaux derives de peroxyde, leur procede de preparation et leur utilisation en medecine humaine et dans des cosmetiques pour le traitement ou la prevention de l'acne
AU2010329840A AU2010329840B2 (en) 2009-12-10 2010-12-10 Novel peroxide derivatives, their process of preparation and their use in human medicine and in cosmetics for the treatment or prevention of acne
CN201080063361.0A CN102741225B (zh) 2009-12-10 2010-12-10 新型过氧化物衍生物、其制备方法及其在人类医学中和在用于治疗或防止痤疮的化妆品中的用途
RS20140424A RS53463B (sr) 2009-12-10 2010-12-10 Novi derivati peroksida, njihov postupak dobijanja i njihova upotreba u humanoj medicini u lečenju ili prevenciji akni
EP10790945.9A EP2509944B1 (fr) 2009-12-10 2010-12-10 Nouveaux dérivés de peroxyde, leur procédé de préparation et leur utilisation en médecine humaine et dans des cosmétiques pour le traitement ou la prévention de l'acné
BR112012013538-4A BR112012013538B1 (pt) 2009-12-10 2010-12-10 Compound
CY20141100693T CY1115510T1 (el) 2009-12-10 2014-08-28 Πρωτοτυπα παραγωγα υπεροξειδιου, η διαδικασια παραγωγης τους και η χρηση τους σε ιατρικη και σε καλλυντικα για την θεραπευτικη ή προληπτικη αγωγη ακμης
SM201400140T SMT201400140B (it) 2009-12-10 2014-09-25 Derivati innovativi di perossidi, loro processo dipreparazione e loro uso nella medicina umana e ne lla cosmetica per il trattamento o la prevenzione dell'acne

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0958846A FR2953832B1 (fr) 2009-12-10 2009-12-10 Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne

Publications (2)

Publication Number Publication Date
FR2953832A1 FR2953832A1 (fr) 2011-06-17
FR2953832B1 true FR2953832B1 (fr) 2012-01-13

Family

ID=42358197

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0958846A Expired - Fee Related FR2953832B1 (fr) 2009-12-10 2009-12-10 Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne

Country Status (20)

Country Link
US (1) US9102607B2 (fr)
EP (1) EP2509944B1 (fr)
JP (1) JP5696159B2 (fr)
KR (1) KR101593263B1 (fr)
CN (1) CN102741225B (fr)
AU (1) AU2010329840B2 (fr)
BR (1) BR112012013538B1 (fr)
CA (1) CA2782948C (fr)
CY (1) CY1115510T1 (fr)
DK (1) DK2509944T3 (fr)
ES (1) ES2491640T3 (fr)
FR (1) FR2953832B1 (fr)
HR (1) HRP20140793T1 (fr)
MX (1) MX2012006217A (fr)
PL (1) PL2509944T3 (fr)
PT (1) PT2509944E (fr)
RS (1) RS53463B (fr)
SI (1) SI2509944T1 (fr)
SM (1) SMT201400140B (fr)
WO (1) WO2011070170A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2580003B1 (fr) 2010-06-08 2017-01-25 Coating Management Switzerland GmbH Procédé de production de tuyaux sans soudure
AU2020251030A1 (en) 2019-04-04 2021-12-02 Galderma Holding SA Isopropylcarbonate benzoyl peroxide compositions and methods of use

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL248201A (fr) 1959-02-11 1900-01-01
GB1054124A (fr) 1964-03-31
NL7210300A (fr) * 1971-08-10 1973-02-13
JPS5163147A (ja) * 1974-11-26 1976-06-01 Yoshitomi Pharmaceutical Shinkisarichiruaniraido karubaminsanesuteruno seizoho
HU173047B (hu) * 1975-03-20 1979-02-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh salicilanilidov
US4355028A (en) 1978-04-04 1982-10-19 Westwood Pharmaceuticals, Inc. Composition for treating acne vulgaris
US4505896A (en) 1979-04-19 1985-03-19 Elorac, Ltd. Method of treating acne vulgaris and composition
GB2068228B (en) 1980-01-24 1984-02-29 Janssen Pharmaceutica Nv Anti-microbial compositions for the topical treatment of acne vulgaris
IT1210608B (it) 1980-12-08 1989-09-14 Rorer Int Overseas Composizione per il trattamento topico dell'acne
IT1194790B (it) * 1981-02-06 1988-09-28 Selvi & C Spa Derivati dell'acido salicilico
US4364940A (en) * 1981-02-23 1982-12-21 Usv Pharmaceutical Corporation Compositions for treating acne
US4514385A (en) 1981-10-05 1985-04-30 Alcon Laboratories, Inc. Anti-acne compositions
US4520133A (en) * 1983-08-11 1985-05-28 Richardson-Vicks Inc. Monohydroxy-benzoyl peroxide and compositions for treating acne
FR2581542B1 (fr) 1985-05-07 1988-02-19 Oreal Compositions topiques destinees au traitement de la peau a base de derives de l'acide salicylique
US4762945A (en) * 1985-09-12 1988-08-09 Usv Pharmaceutical Corporation Process for the preparation of aspirin peroxide
FR2604435B1 (fr) * 1986-09-30 1988-12-02 Oreal Peroxydes aromatiques insatures et leur utilisation en therapeutique et cosmetique
FR2607498B1 (fr) 1986-12-01 1991-04-05 Oreal Nouveaux salicylates lipophiles d'ammoniums quaternaires, leur utilisation en cosmetique et en dermopharmacie
US5409917A (en) 1991-03-05 1995-04-25 Marvin S. Towsend Topical treatment of acne with cephalosporins
TW224048B (fr) 1992-03-30 1994-05-21 Hoechst Roussel Pharma
US5439923A (en) 1993-12-21 1995-08-08 Eli Lilly And Company Method of inhibiting seborrhea and acne
EP1219682B1 (fr) 2000-12-21 2003-02-05 ILFORD Imaging Switzerland GmbH Colorants monoazoiques, leur préparation et leur utilisation
NO326916B1 (no) * 2006-11-20 2009-03-16 Visuray As Framgangsmate for nedihulls, ikke-isotopisk framstilling av noytroner samt apparat for anvendelse ved utovelse av framgangsmaten

Also Published As

Publication number Publication date
EP2509944B1 (fr) 2014-06-18
CY1115510T1 (el) 2017-01-04
ES2491640T3 (es) 2014-09-08
WO2011070170A1 (fr) 2011-06-16
KR101593263B1 (ko) 2016-02-11
FR2953832A1 (fr) 2011-06-17
US9102607B2 (en) 2015-08-11
JP5696159B2 (ja) 2015-04-08
RS53463B (sr) 2014-12-31
CN102741225B (zh) 2015-10-21
CA2782948A1 (fr) 2011-06-16
MX2012006217A (es) 2012-07-03
SI2509944T1 (sl) 2014-10-30
HRP20140793T1 (hr) 2014-09-26
JP2013513580A (ja) 2013-04-22
AU2010329840A1 (en) 2012-07-12
BR112012013538A2 (pt) 2016-08-02
AU2010329840B2 (en) 2014-08-21
PL2509944T3 (pl) 2014-11-28
SMT201400140B (it) 2014-11-10
EP2509944A1 (fr) 2012-10-17
US20120323035A1 (en) 2012-12-20
CN102741225A (zh) 2012-10-17
RU2012128869A (ru) 2014-01-20
BR112012013538B1 (pt) 2017-12-12
KR20120089774A (ko) 2012-08-13
CA2782948C (fr) 2015-02-10
DK2509944T3 (da) 2014-09-01
PT2509944E (pt) 2014-08-06

Similar Documents

Publication Publication Date Title
FR2937972B1 (fr) Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2937973B1 (fr) Modulateurs des recepteurs de la melanocortine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
EP2528603A4 (fr) Compositions pharmaceutiques pour le traitement de la douleur et d'autres indications
UA109650C2 (xx) Біс-арилзв'язані арилтриазолони та їх застосування
EP2651407A4 (fr) 3-méthanesulfonylpropionitrile pour le traitement d'une inflammation et de la douleur
EP2532680A4 (fr) Composition médicinale pour le traitement et/ou la prévention du cancer
EP2916827A4 (fr) Procédés et dispositifs pour le traitement de maladies oculaires chez des sujets humains
MX2011009539A (es) 2-acetamido-5-aril-1,2,4-triazolonas sustituidas y su uso.
MA34721B1 (fr) Acides carboxyliques 1-benzylcycloalkyle substitués et leur utilisation
EP2651439A4 (fr) Compositions et procédés pour le traitement ou la prévention d'une infection par l'adénovirus 36 humain
MX356343B (es) Compuestos que inhiben la exocitosis neuronal (ii).
FR2958163B1 (fr) Preparation issue d'une culture in vitro de cellules dedifferencieres non elicitees d'arganier, leur utilisation pour le traitement du vieillissement cutane, de l'inflammation et de la cicatrisation, et leur obtention.
EP2827847A4 (fr) Complexes contenant du strontium administré par voie topique pour le traitement de la douleur, du prurit et de l'inflammation
FR2994386B1 (fr) Inhibition de l'adhesion de micro-organismes pathogenes par un ester de saccharose et/ou de sorbitan dans le traitement cosmetique de l'atopie cutanee
FR2939136B1 (fr) Nouveaux composes 4-(heterocycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
EP2817017A4 (fr) Médicament contenant de l'extrait de racine de taraxacum pour le traitement ou la prévention du cancer, et sa méthode de préparation
FR2935380B1 (fr) Nouveaux composes hexafluoro-2-biphenyl-isopropanol, modulateurs des recepteurs de type lxrs, leur procede de preparation et leur application comme medicaments en medecine humaine ou veterinaire ainsi qu'en cosmetique.
FR2937868B1 (fr) Composes antagonistes des recepteurs de la melanocortine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
FR2922450B1 (fr) Utilisation de bacteries lactique pour la prevention et/ou le traitement de pathologies cutanees
FR2917087B1 (fr) Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique.
EP2548893A4 (fr) Antagoniste double pour le tnf- et l'il-21 dans la prévention et le traitement de maladies auto-immunes
FR2953832B1 (fr) Derives de nouveaux peroxydes, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique pour le traitement ou la prevention de l'acne
FR2917089B1 (fr) Nouveaux 4-heteroaryl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique.
EP2838508A4 (fr) Formulations et procédés pour le traitement de l'acné et d'affections cutanées inflammatoires
UA109359C2 (xx) Лікування захворювань і станів шкіри 7-(1h-імідазол-4-ілметил)-5,6,7,8-тетрагідрохіноліном

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 9

PLFP Fee payment

Year of fee payment: 10

ST Notification of lapse

Effective date: 20200910