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FR2881436B1 - Procede de determination de la diversite des lymphocytes t dans un echantillon biologique - Google Patents

Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Info

Publication number
FR2881436B1
FR2881436B1 FR0501073A FR0501073A FR2881436B1 FR 2881436 B1 FR2881436 B1 FR 2881436B1 FR 0501073 A FR0501073 A FR 0501073A FR 0501073 A FR0501073 A FR 0501073A FR 2881436 B1 FR2881436 B1 FR 2881436B1
Authority
FR
France
Prior art keywords
lymphocytes
diversity
determining
biological sample
biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0501073A
Other languages
English (en)
Other versions
FR2881436A1 (fr
Inventor
Serge Candeias
Cedric Touvrey
Marche Evelyne Jouvin
Patrice Marche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0501073A priority Critical patent/FR2881436B1/fr
Priority to US11/883,633 priority patent/US20080286777A1/en
Priority to EP06709239A priority patent/EP1846574A1/fr
Priority to JP2007553658A priority patent/JP2008528049A/ja
Priority to PCT/FR2006/000247 priority patent/WO2006082324A1/fr
Priority to CA002596389A priority patent/CA2596389A1/fr
Publication of FR2881436A1 publication Critical patent/FR2881436A1/fr
Application granted granted Critical
Publication of FR2881436B1 publication Critical patent/FR2881436B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR0501073A 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique Expired - Fee Related FR2881436B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0501073A FR2881436B1 (fr) 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
US11/883,633 US20080286777A1 (en) 2005-02-03 2006-02-03 Method of Determining the Diversity of T Lymphocytes in a Biological Sample
EP06709239A EP1846574A1 (fr) 2005-02-03 2006-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
JP2007553658A JP2008528049A (ja) 2005-02-03 2006-02-03 生物学的サンプル中のｔリンパ球の多様性を決定する方法
PCT/FR2006/000247 WO2006082324A1 (fr) 2005-02-03 2006-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique
CA002596389A CA2596389A1 (fr) 2005-02-03 2006-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0501073A FR2881436B1 (fr) 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Publications (2)

Publication Number Publication Date
FR2881436A1 FR2881436A1 (fr) 2006-08-04
FR2881436B1 true FR2881436B1 (fr) 2007-04-27

Family

ID=34953893

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0501073A Expired - Fee Related FR2881436B1 (fr) 2005-02-03 2005-02-03 Procede de determination de la diversite des lymphocytes t dans un echantillon biologique

Country Status (6)

Country Link
US (1) US20080286777A1 (fr)
EP (1) EP1846574A1 (fr)
JP (1) JP2008528049A (fr)
CA (1) CA2596389A1 (fr)
FR (1) FR2881436B1 (fr)
WO (1) WO2006082324A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691510B2 (en) * 2008-11-07 2014-04-08 Sequenta, Inc. Sequence analysis of complex amplicons
US9506119B2 (en) 2008-11-07 2016-11-29 Adaptive Biotechnologies Corp. Method of sequence determination using sequence tags
US8628927B2 (en) 2008-11-07 2014-01-14 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US8748103B2 (en) 2008-11-07 2014-06-10 Sequenta, Inc. Monitoring health and disease status using clonotype profiles
US9365901B2 (en) 2008-11-07 2016-06-14 Adaptive Biotechnologies Corp. Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
CN102272327B (zh) 2008-11-07 2015-11-25 赛昆塔公司 通过序列分析监测状况的方法
US9528160B2 (en) 2008-11-07 2016-12-27 Adaptive Biotechnolgies Corp. Rare clonotypes and uses thereof
DK2387627T3 (en) 2009-01-15 2016-07-04 Adaptive Biotechnologies Corp Adaptive immunity profiling and methods for producing monoclonal antibodies
RU2539032C2 (ru) 2009-06-25 2015-01-10 Фред Хатчинсон Кансэр Рисёч Сентер Способ измерения искусственного иммунитета
US9043160B1 (en) 2009-11-09 2015-05-26 Sequenta, Inc. Method of determining clonotypes and clonotype profiles
US10385475B2 (en) 2011-09-12 2019-08-20 Adaptive Biotechnologies Corp. Random array sequencing of low-complexity libraries
HK1201565A1 (en) 2011-10-21 2015-09-04 Adaptive Biotechnologies Corporation Quantification of adaptive immune cell genomes in a complex mixture of cells
EP2788509B1 (fr) 2011-12-09 2018-07-11 Adaptive Biotechnologies Corporation Diagnostic des malignités lymphoïdes et détection de maladie résiduelle minimale
US9499865B2 (en) 2011-12-13 2016-11-22 Adaptive Biotechnologies Corp. Detection and measurement of tissue-infiltrating lymphocytes
ES2662128T3 (es) 2012-03-05 2018-04-05 Adaptive Biotechnologies Corporation Determinación de cadenas de receptor inmunitario emparejadas a partir de la frecuencia de subunidades coincidentes
US9150905B2 (en) 2012-05-08 2015-10-06 Adaptive Biotechnologies Corporation Compositions and method for measuring and calibrating amplification bias in multiplexed PCR reactions
JP6449160B2 (ja) 2012-10-01 2019-01-09 アダプティブ バイオテクノロジーズ コーポレイション 適応免疫受容体多様性およびクローン性特性決定による免疫能力評価関連出願の相互参照
WO2015160439A2 (fr) 2014-04-17 2015-10-22 Adaptive Biotechnologies Corporation Quantification de génomes de cellules de l'immunité acquise dans un mélange complexe de cellules
US9708657B2 (en) 2013-07-01 2017-07-18 Adaptive Biotechnologies Corp. Method for generating clonotype profiles using sequence tags
ES2741740T3 (es) 2014-03-05 2020-02-12 Adaptive Biotechnologies Corp Métodos que usan moléculas sintéticas que contienen segmentos de nucleótidos aleatorios
US10066265B2 (en) 2014-04-01 2018-09-04 Adaptive Biotechnologies Corp. Determining antigen-specific t-cells
EP3715455A1 (fr) 2014-10-29 2020-09-30 Adaptive Biotechnologies Corp. Détection simultanée hautement multiplexée d'acides nucléiques codant pour des hétérodimères de récepteurs de l'immunité adaptative appariés à partir de nombreux échantillons
US10246701B2 (en) 2014-11-14 2019-04-02 Adaptive Biotechnologies Corp. Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
CA2968543C (fr) 2014-11-25 2024-04-02 Adaptive Biotechnologies Corporation Caracterisation de la reponse immunitaire adaptative a la vaccination ou a l'infection a l'aide du sequencage du repertoire immunitaire
US11047008B2 (en) 2015-02-24 2021-06-29 Adaptive Biotechnologies Corporation Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
WO2016161273A1 (fr) 2015-04-01 2016-10-06 Adaptive Biotechnologies Corp. Procédé d'identification des récepteurs de lymphocytes t spécifiques à compatibilité humaine pour une cible antigénique
US10428325B1 (en) 2016-09-21 2019-10-01 Adaptive Biotechnologies Corporation Identification of antigen-specific B cell receptors
US11254980B1 (en) 2017-11-29 2022-02-22 Adaptive Biotechnologies Corporation Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
CN113640803B (zh) * 2021-09-01 2022-07-22 江西师范大学 一种基于回波强度和回波顶高外推的短时定量降水预报方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235504B1 (en) * 1999-01-11 2001-05-22 The Rockefeller University Methods for identifying genomic equivalent markers and their use in quantitating cells and polynucleotide sequences therein
US20030228586A1 (en) * 1999-06-30 2003-12-11 Rafick-Pierre Sekaly Method for measuring de novo T-cell production in humans
DE60225441T2 (de) * 2001-04-13 2009-02-26 Institut National De La Santé Et De La Recherche Médicale (Inserm) Verfahren zur analyse von t-lymphozyten über die t-lymphozytrezeptoren eines organismus

Also Published As

Publication number Publication date
WO2006082324A1 (fr) 2006-08-10
JP2008528049A (ja) 2008-07-31
CA2596389A1 (fr) 2006-08-10
FR2881436A1 (fr) 2006-08-04
US20080286777A1 (en) 2008-11-20
EP1846574A1 (fr) 2007-10-24

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Effective date: 20111102