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FR2877668B1 - Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations - Google Patents

Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations

Info

Publication number
FR2877668B1
FR2877668B1 FR0452591A FR0452591A FR2877668B1 FR 2877668 B1 FR2877668 B1 FR 2877668B1 FR 0452591 A FR0452591 A FR 0452591A FR 0452591 A FR0452591 A FR 0452591A FR 2877668 B1 FR2877668 B1 FR 2877668B1
Authority
FR
France
Prior art keywords
final product
product obtained
intermediate compound
immunogenic molecules
coupling non
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0452591A
Other languages
English (en)
Other versions
FR2877668A1 (fr
Inventor
Michel Geffard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Polyneuros SAS
Original Assignee
GEMAC SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEMAC SA filed Critical GEMAC SA
Priority to FR0452591A priority Critical patent/FR2877668B1/fr
Priority to PCT/FR2005/050942 priority patent/WO2006051241A2/fr
Publication of FR2877668A1 publication Critical patent/FR2877668A1/fr
Application granted granted Critical
Publication of FR2877668B1 publication Critical patent/FR2877668B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR0452591A 2004-11-10 2004-11-10 Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations Expired - Fee Related FR2877668B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0452591A FR2877668B1 (fr) 2004-11-10 2004-11-10 Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations
PCT/FR2005/050942 WO2006051241A2 (fr) 2004-11-10 2005-11-10 Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0452591A FR2877668B1 (fr) 2004-11-10 2004-11-10 Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations

Publications (2)

Publication Number Publication Date
FR2877668A1 FR2877668A1 (fr) 2006-05-12
FR2877668B1 true FR2877668B1 (fr) 2007-07-06

Family

ID=34954138

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0452591A Expired - Fee Related FR2877668B1 (fr) 2004-11-10 2004-11-10 Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations

Country Status (2)

Country Link
FR (1) FR2877668B1 (fr)
WO (1) WO2006051241A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008732B (zh) * 2010-11-08 2012-10-24 武汉华耀生物医药有限公司 一种叶酸偶联抗体药物及其制备方法与应用
EP3568157A4 (fr) * 2017-01-13 2021-01-06 National Research Council of Canada Procédé d'optimisation d'immuno-épitope peptidique par glycosylation, peptide optimisé associé et son utilisation pour des vaccins conjugués

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876727A (en) * 1995-03-31 1999-03-02 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
EP1015028A2 (fr) * 1997-09-19 2000-07-05 Serex, Inc. Procede permettant d'ameliorer l'immunogenicite des antigenes et la specificite des anticorps

Also Published As

Publication number Publication date
WO2006051241A2 (fr) 2006-05-18
FR2877668A1 (fr) 2006-05-12
WO2006051241A3 (fr) 2006-11-09

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Legal Events

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Year of fee payment: 12

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Effective date: 20200311

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Effective date: 20200906