[go: up one dir, main page]

FR2874612A1 - Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications - Google Patents

Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications

Info

Publication number
FR2874612A1
FR2874612A1 FR0409140A FR0409140A FR2874612A1 FR 2874612 A1 FR2874612 A1 FR 2874612A1 FR 0409140 A FR0409140 A FR 0409140A FR 0409140 A FR0409140 A FR 0409140A FR 2874612 A1 FR2874612 A1 FR 2874612A1
Authority
FR
France
Prior art keywords
hla
totes
restricted hiv
hiv
restricted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR0409140A
Other languages
English (en)
Inventor
William Cohen
Moratille Sandra Pouvelle
Gaetan Munier
Bernard Maillere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0409140A priority Critical patent/FR2874612A1/fr
Priority to PCT/FR2005/002152 priority patent/WO2006027468A2/fr
Publication of FR2874612A1 publication Critical patent/FR2874612A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente Invention est relative à des peptides antigéniques du virus de l'immunodéficience humaine (VIH) comprenant au moins un épitope T CD4+ qui est restreint à une molécule HLA-DP4, et à leurs applications vaccinales et diagnostiques.
FR0409140A 2004-08-27 2004-08-27 Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications Withdrawn FR2874612A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0409140A FR2874612A1 (fr) 2004-08-27 2004-08-27 Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications
PCT/FR2005/002152 WO2006027468A2 (fr) 2004-08-27 2005-08-26 Epitopes t cd4+ du vih restreints a hla-dp4 et leurs applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0409140A FR2874612A1 (fr) 2004-08-27 2004-08-27 Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications

Publications (1)

Publication Number Publication Date
FR2874612A1 true FR2874612A1 (fr) 2006-03-03

Family

ID=34948781

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0409140A Withdrawn FR2874612A1 (fr) 2004-08-27 2004-08-27 Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications

Country Status (2)

Country Link
FR (1) FR2874612A1 (fr)
WO (1) WO2006027468A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830940B1 (fr) 2001-10-17 2007-06-15 Commissariat Energie Atomique Procede de selection de ligands d'hla-dp4 et ses applications
WO2007039458A2 (fr) * 2005-09-21 2007-04-12 Cytos Biotechnology Ag Conjugues peptidiques du vih et leurs utilisations
CN104427991A (zh) * 2012-06-27 2015-03-18 耶达研究与发展有限公司 用于治疗t细胞介导的病理的来源于hiv gp41 的肽

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998032456A1 (fr) * 1997-01-23 1998-07-30 Epimmune, Inc. Identification d'epitopes a restriction dr largement reactifs
WO2001024810A1 (fr) * 1999-10-05 2001-04-12 Epimmune Inc. Induction de reponses immunitaires cellulaires au virus de l'immunodeficience humaine de type 1 a l'aide de compositions de peptides et d'acides nucleiques
US20040001851A1 (en) * 2001-11-07 2004-01-01 Haynes Barton F. Polyvalent immunogen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330359A3 (fr) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Composition utile pour le diagnostic et le traitement de l'infection par le HIV-I
EP0339504A3 (fr) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Virus d'immunodéficience humaine (HIV) peptide env-codé capable de provoquer les anticorps inhibiteurs du HIV dans les mammifères
US5696238A (en) * 1991-08-20 1997-12-09 Chiron Corporation Purified GP120 composition retaining natural conformation
EP0572737B1 (fr) * 1992-06-04 2001-02-28 The Research Foundation For Microbial Diseases Of Osaka University Antigène fusion gag-env de HIV
NZ544011A (en) * 2003-06-10 2009-02-28 Univ Melbourne Immunomodulating compositions uses therefor and processes for their production

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998032456A1 (fr) * 1997-01-23 1998-07-30 Epimmune, Inc. Identification d'epitopes a restriction dr largement reactifs
WO2001024810A1 (fr) * 1999-10-05 2001-04-12 Epimmune Inc. Induction de reponses immunitaires cellulaires au virus de l'immunodeficience humaine de type 1 a l'aide de compositions de peptides et d'acides nucleiques
US20040001851A1 (en) * 2001-11-07 2004-01-01 Haynes Barton F. Polyvalent immunogen

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
NAKAMURA Y ET AL: "A chain section containing epitopes for cytotoxic T, B and helper T cells within a highly conserved region found in the human immunodeficiency virus type 1 Gag protein", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 15, no. 5, 5 April 1997 (1997-04-05), pages 489 - 496, XP004059887, ISSN: 0264-410X *
NISHINO Y ET AL: "IN VIVO INDUCTION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1-SPECIFIC CYTOTOXIC T LYMPHOCYTES AND DELAYED-TYPE HYPERSENSITIVITY BY A 23-AMINO ACID PEPTIDE FROM THE HIGHLY CONSERVED REGION IN MAJOR CORE PROTEIN P24", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 12, no. 6, May 1994 (1994-05-01), pages 485 - 491, XP000882395, ISSN: 0264-410X *
PANCRÉ V ET AL.: "Novel promiscuous HLA-DQ HIV Nef peptide that induces IFN-gamma-producing memory CD4+ T cells", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 129, 2002, pages 429 - 437, XP002321844 *
SONG YUB SHIN ET AL: "CHARACTERIZATION OF KI-24, A NOVEL MURINE MONOCLONAL ANTIBODY WITH SPECIFIC REACTIVITY FOR THE HUMAN IMMUNODEFICIENCY VIRUS-1 P24 PROTEIN", JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. 33, no. 1, 31 January 2000 (2000-01-31), pages 92 - 95, XP009040726, ISSN: 1225-8687 *

Also Published As

Publication number Publication date
WO2006027468A2 (fr) 2006-03-16
WO2006027468A3 (fr) 2006-06-29

Similar Documents

Publication Publication Date Title
PL397776A1 (pl) Kompleks rozpuszczalny obejmujący retrowirusową glikoproteinę powierzchniową oraz kompozycja obejmująca ten kompleks
CY1108299T1 (el) Πεπτιδια του ιου ανθρωπινης ανοσοανεπαρκειας (hiv), αντιγονα και συνθεσεις εμβολιου
SG155206A1 (en) Vaccine for prevention and treatment of hiv-infection
CY1107146T1 (el) Μεθοδοι για προληψη και θεραπεια ασθενειας alzheimer (ad)
MY136081A (en) Modified hiv - 1gag p17 peptide and immunogenic composition
EA200200724A1 (ru) Вакцина для профилактической или терапевтической иммунизации против вируса иммунодефицита человека (вич)
BR9814487A (pt) "vacina"
BR0211296A (pt) Peptìdeo imunogênico derivado da proteìna g do vrs do sub-grupo a ou b, sequência de ácido nucleico, composição farmacêutica, anticorpos policlonais ou monoclonais, kit de diagnóstico, utilização de um peptìdeo imunogênico, e, conjugado
BR0108210A (pt) Vacina contra o vìrus da imunodeficiência humana
ATE306938T1 (de) Verwendung von cpg als adjuvans für hivimpstoff
DK1255815T3 (da) Porcint reproduktivt og respiratorisk syndromvirus til fremgangsmåder til anvendelse
DE602006011859D1 (de) T-cd4+-epitope der latenzantigene typ i und ii des epstein-barr-virus, die bei der mehrzahl von individuen in der kaukasischen bevölkerung erkannt werden können, und anwendungen davon
CY1111567T1 (el) Ενδιαμεσα διβενζο (b,f) αζεπινης
FR2647810B1 (fr) Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
NO20014841D0 (no) Anti-HIV-1 vaksine som omfatter hele eller del av HIV-1 TAT proteinet
FR2874612A1 (fr) Epitotes t cd4+ du vih restreints a hla-dp4 et leurs applications
MA34215B1 (fr) Traitement d'association comprenant un antagoniste du récepteur ccr5, un inhibiteur de la protéase du vih-1 et un accélérateur pharmacocinétique
DK1765337T3 (da) Kombination af tenofovir, ritonavir og TMC114
FR2868318B1 (fr) Antigene tat stabilise et ses applications pour la vaccination anti-vih
JP2007516701A5 (fr)
CA2519012C (fr) Procede pour evaluer in vitro l'etat de progression d'une infection par le virus vih chez un individu
WO2003029285A3 (fr) Identification de nouveaux epitopes cd8 des proteines du vih-1 presentant des proprietes therapeutiques et vaccinales contre les infection par le vih
WO2002026785A3 (fr) Epitopes du virus de l'hepatite c specifiques des lymphocytes t cd4?+¿
CY1105629T1 (el) Πολυπεπτιδιο που επαγει αντισωματα εξουδετερωσης του ηιv
WO2004108886A3 (fr) Composes anti-vih-1 a base de sequences d'acides amines conserves partages par gp160 et la proteine humaine cd4

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20080430