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FR2841250B1 - Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant - Google Patents

Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant

Info

Publication number
FR2841250B1
FR2841250B1 FR0207562A FR0207562A FR2841250B1 FR 2841250 B1 FR2841250 B1 FR 2841250B1 FR 0207562 A FR0207562 A FR 0207562A FR 0207562 A FR0207562 A FR 0207562A FR 2841250 B1 FR2841250 B1 FR 2841250B1
Authority
FR
France
Prior art keywords
interferon
preparation
same
binding compounds
medicaments containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0207562A
Other languages
English (en)
Other versions
FR2841250A1 (fr
Inventor
David Bonnaffe
Andre Lubineau
Jocelyne Alais
Olivier Gavard
Anna Dilhas
Jacob Hugues Lortat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Paris Sud
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Commissariat a lEnergie Atomique CEA
Universite Paris Sud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0207562A priority Critical patent/FR2841250B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Commissariat a lEnergie Atomique CEA, Universite Paris Sud filed Critical Centre National de la Recherche Scientifique CNRS
Priority to PCT/FR2003/001860 priority patent/WO2004000887A1/fr
Priority to CA002489561A priority patent/CA2489561A1/fr
Priority to AU2003260601A priority patent/AU2003260601A1/en
Priority to JP2004514944A priority patent/JP2005533881A/ja
Priority to US10/518,177 priority patent/US20060166927A1/en
Priority to EP03760740A priority patent/EP1521779A1/fr
Publication of FR2841250A1 publication Critical patent/FR2841250A1/fr
Application granted granted Critical
Publication of FR2841250B1 publication Critical patent/FR2841250B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR0207562A 2002-06-19 2002-06-19 Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant Expired - Fee Related FR2841250B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0207562A FR2841250B1 (fr) 2002-06-19 2002-06-19 Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant
CA002489561A CA2489561A1 (fr) 2002-06-19 2003-06-18 Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant
AU2003260601A AU2003260601A1 (en) 2002-06-19 2003-06-18 Compounds that bind to the interferon-gamma, preparation method thereof and medicaments containing same
JP2004514944A JP2005533881A (ja) 2002-06-19 2003-06-18 ガンマ・インターフェロン結合性化合物、それらの調製法、およびそれらを含有する薬物
PCT/FR2003/001860 WO2004000887A1 (fr) 2002-06-19 2003-06-18 Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant
US10/518,177 US20060166927A1 (en) 2002-06-19 2003-06-18 Compounds that bind to the interferon-gamma, preparation method thereof and medicaments containing same
EP03760740A EP1521779A1 (fr) 2002-06-19 2003-06-18 Composes se liant a l interferon-gamma, leur procede de preparation, et medicaments les contenant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0207562A FR2841250B1 (fr) 2002-06-19 2002-06-19 Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant

Publications (2)

Publication Number Publication Date
FR2841250A1 FR2841250A1 (fr) 2003-12-26
FR2841250B1 true FR2841250B1 (fr) 2004-07-23

Family

ID=29719874

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0207562A Expired - Fee Related FR2841250B1 (fr) 2002-06-19 2002-06-19 Composes se liant a l'interferon-gamma, leur procede de preparation, et medicaments les contenant

Country Status (7)

Country Link
US (1) US20060166927A1 (fr)
EP (1) EP1521779A1 (fr)
JP (1) JP2005533881A (fr)
AU (1) AU2003260601A1 (fr)
CA (1) CA2489561A1 (fr)
FR (1) FR2841250B1 (fr)
WO (1) WO2004000887A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2904627B1 (fr) * 2006-08-04 2008-11-07 Pasteur Institut Nouveaux peptides actives, purifies et isoles, derives du recepteur cd4 (mini-cd4) et leur procece de preparation
EP2087911A1 (fr) 2008-02-06 2009-08-12 Institut Pasteur Molécules conjuguées comprenant un peptide dérivé du récepteur CD4 couplé à un polyanion pour le traitement du SIDA
CN102702281A (zh) * 2012-05-30 2012-10-03 济南圣泉唐和唐生物科技有限公司 提纯3-O-苄基-1,2-O-异亚丙基-β-L-艾杜呋喃糖醛酸甲酯的方法
CN102675382B (zh) * 2012-05-30 2014-08-13 济南圣泉唐和唐生物科技有限公司 3-O-苄基-1,2-O-异亚丙基-6-氧-α-D-呋喃葡糖酐-6-苯基硫代原酸酯的制备方法
CN111978360B (zh) * 2020-09-02 2022-11-25 华东理工大学 石莼b3s型硫酸寡糖类化合物及其制备方法和应用
CN116251174B (zh) * 2022-12-23 2023-09-29 北京三元基因药业股份有限公司 一种包含人干扰素α1b吸入溶液的药物组件

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2736832B1 (fr) * 1995-07-19 1997-09-19 Pasteur Institut Agent potentialisateur de l'interferon-gamma

Also Published As

Publication number Publication date
AU2003260601A1 (en) 2004-01-06
US20060166927A1 (en) 2006-07-27
EP1521779A1 (fr) 2005-04-13
AU2003260601A8 (en) 2004-01-06
CA2489561A1 (fr) 2003-12-31
JP2005533881A (ja) 2005-11-10
WO2004000887A1 (fr) 2003-12-31
FR2841250A1 (fr) 2003-12-26

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20110228