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FR2840611B1 - Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations - Google Patents

Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations

Info

Publication number
FR2840611B1
FR2840611B1 FR0206948A FR0206948A FR2840611B1 FR 2840611 B1 FR2840611 B1 FR 2840611B1 FR 0206948 A FR0206948 A FR 0206948A FR 0206948 A FR0206948 A FR 0206948A FR 2840611 B1 FR2840611 B1 FR 2840611B1
Authority
FR
France
Prior art keywords
oligonucleotide
functional group
covalently associated
fluorescent entity
fluorophore covalently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0206948A
Other languages
English (en)
Other versions
FR2840611A1 (fr
Inventor
Eric Trinquet
Fabrice Maurin
Herve Bazin
Gerard Mathis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Priority to FR0206948A priority Critical patent/FR2840611B1/fr
Priority to AU2003242733A priority patent/AU2003242733A1/en
Priority to EP03757066A priority patent/EP1525211A2/fr
Priority to US10/516,744 priority patent/US20050239073A1/en
Priority to PCT/EP2003/006459 priority patent/WO2003104685A2/fr
Priority to JP2004511721A priority patent/JP2005529219A/ja
Publication of FR2840611A1 publication Critical patent/FR2840611A1/fr
Application granted granted Critical
Publication of FR2840611B1 publication Critical patent/FR2840611B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
FR0206948A 2002-06-06 2002-06-06 Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations Expired - Fee Related FR2840611B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0206948A FR2840611B1 (fr) 2002-06-06 2002-06-06 Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations
AU2003242733A AU2003242733A1 (en) 2002-06-06 2003-06-06 Fluorescent entity comprising a fluorophore covalently attached to at least one oligonucleotide and comprising at least one functional group, and uses thereof
EP03757066A EP1525211A2 (fr) 2002-06-06 2003-06-06 Entite fluorescente comprenant un fluorophore en liaison covalente avec au moins un oligonucleotide et comprenant au moins un groupe fonctionnel, et ses applications
US10/516,744 US20050239073A1 (en) 2002-06-06 2003-06-06 Fluorescent entity comprising a fluorophore covalently attached to at least one oligonucleotide and comprising at least one functional group, and uses thereof
PCT/EP2003/006459 WO2003104685A2 (fr) 2002-06-06 2003-06-06 Entite fluorescente comprenant un fluorophore en liaison covalente avec au moins un oligonucleotide et comprenant au moins un groupe fonctionnel, et ses applications
JP2004511721A JP2005529219A (ja) 2002-06-06 2003-06-06 少なくとも１のオリゴヌクレオチドに共有結合するフルオロフォアを含みかつ少なくとも１の官能基を含む蛍光物質、並びにその使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0206948A FR2840611B1 (fr) 2002-06-06 2002-06-06 Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations

Publications (2)

Publication Number Publication Date
FR2840611A1 FR2840611A1 (fr) 2003-12-12
FR2840611B1 true FR2840611B1 (fr) 2005-09-09

Family

ID=29559003

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0206948A Expired - Fee Related FR2840611B1 (fr) 2002-06-06 2002-06-06 Entite fluorescente comportant un fluorophore lie de maniere covalente a au moins un oligonucleotide et comportant au moins un groupe fonctionnel et ses utilisations

Country Status (6)

Country Link
US (1) US20050239073A1 (fr)
EP (1) EP1525211A2 (fr)
JP (1) JP2005529219A (fr)
AU (1) AU2003242733A1 (fr)
FR (1) FR2840611B1 (fr)
WO (1) WO2003104685A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2890446B1 (fr) 2005-09-05 2008-04-18 Cis Bio Internat Sa Methode de detection d'interaction intracellulaire entre bio-molecules
WO2007135368A2 (fr) 2006-05-18 2007-11-29 Solexa Limited Composés de type teinte et application de leurs conjugués marqués
DE202008009713U1 (de) * 2008-06-26 2009-08-06 InBio Prof. Jürgen Büddefeld Dr. Peter Klauth Prof. Manfred Rietz GbR (vertretungsberechtigter Gesellschafter: Dr. Peter Klauth, 41189 Mönchengladbach) Abstandsgesteuerte Energietransfer-Farbstoffkomplexe
CN102702768B (zh) * 2012-06-04 2013-12-04 天津理工大学 一种新型红光bodipy荧光染料及其制备方法和应用
KR102292609B1 (ko) * 2017-04-13 2021-08-23 미시간 테크놀로지컬 유니버시티 고-휘도 형광단

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3143566A (en) * 1959-10-08 1964-08-04 Sterling Drug Inc Nu, nu'-di-[halogenated-(lower-alkanoyl)]-diamine compositions and their preparation
US4849513A (en) * 1983-12-20 1989-07-18 California Institute Of Technology Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
DE3642939A1 (de) * 1986-06-03 1987-12-10 Europ Lab Molekularbiolog Verfahren zur dna-markierung
AU7579991A (en) * 1990-02-20 1991-09-18 Gilead Sciences, Inc. Pseudonucleosides and pseudonucleotides and their polymers
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
US5994063A (en) * 1995-06-23 1999-11-30 Metzker; Michael L. Substituted 4,4-difluoro-4-bora-3A,4A-diaza-s-indacene compounds for homogenous amplification/detection assays
US5650334A (en) * 1995-08-31 1997-07-22 First Medical, Inc. Fluorescent labelling compositions and methods for their use
US5853992A (en) * 1996-10-04 1998-12-29 The Regents Of The University Of California Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels
FR2757162B1 (fr) * 1996-12-12 1999-03-26 Cis Bio Int Conjugues fluorescents non agreges
EP0998577B1 (fr) * 1997-07-24 2004-10-27 Perseptive Biosystems, Inc. Conjugues de peptides transporteurs et analogues d'acides nucleiques ainsi que leur utilisation
US6342326B1 (en) * 2000-05-10 2002-01-29 Beckman Coulter, Inc. Synthesis and use of acyl fluorides of cyanine dyes

Also Published As

Publication number Publication date
AU2003242733A1 (en) 2003-12-22
AU2003242733A8 (en) 2003-12-22
FR2840611A1 (fr) 2003-12-12
JP2005529219A (ja) 2005-09-29
WO2003104685A3 (fr) 2004-04-01
EP1525211A2 (fr) 2005-04-27
US20050239073A1 (en) 2005-10-27
WO2003104685A2 (fr) 2003-12-18

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20140228