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FR2730734B1 - Nouveaux composes manifestant des proprietes inhibitrices de farnesyl transferase et microorganisme du genre chrysosporium susceptible d'etre utilise pour les preparer - Google Patents

Nouveaux composes manifestant des proprietes inhibitrices de farnesyl transferase et microorganisme du genre chrysosporium susceptible d'etre utilise pour les preparer

Info

Publication number
FR2730734B1
FR2730734B1 FR9501866A FR9501866A FR2730734B1 FR 2730734 B1 FR2730734 B1 FR 2730734B1 FR 9501866 A FR9501866 A FR 9501866A FR 9501866 A FR9501866 A FR 9501866A FR 2730734 B1 FR2730734 B1 FR 2730734B1
Authority
FR
France
Prior art keywords
inhibitoring
microorganism
prepare
new compounds
farnesyl transferase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9501866A
Other languages
English (en)
Other versions
FR2730734A1 (fr
Inventor
Jean Jacques Debernard
Jean Leboul
Der Pyl Didier Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Priority to FR9501866A priority Critical patent/FR2730734B1/fr
Priority to CA002211167A priority patent/CA2211167A1/fr
Priority to JP8524700A priority patent/JPH11500615A/ja
Priority to EP96901418A priority patent/EP0809707A1/fr
Priority to US08/894,038 priority patent/US5849724A/en
Priority to PCT/FR1996/000089 priority patent/WO1996025512A1/fr
Publication of FR2730734A1 publication Critical patent/FR2730734A1/fr
Application granted granted Critical
Publication of FR2730734B1 publication Critical patent/FR2730734B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9501866A 1995-02-17 1995-02-17 Nouveaux composes manifestant des proprietes inhibitrices de farnesyl transferase et microorganisme du genre chrysosporium susceptible d'etre utilise pour les preparer Expired - Fee Related FR2730734B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9501866A FR2730734B1 (fr) 1995-02-17 1995-02-17 Nouveaux composes manifestant des proprietes inhibitrices de farnesyl transferase et microorganisme du genre chrysosporium susceptible d'etre utilise pour les preparer
CA002211167A CA2211167A1 (fr) 1995-02-17 1996-01-19 Microorganisme du genre chrysosporium utile pour preparer des inhibiteurs de farnesyl transferase
JP8524700A JPH11500615A (ja) 1995-02-17 1996-01-19 ファルネシルトランスフェラーゼ阻害剤の調製における使用のためのクリソスポリウム（Ｃｈｒｙｓｏｓｐｏｒｉｕｍ）属の微生物
EP96901418A EP0809707A1 (fr) 1995-02-17 1996-01-19 Microorganisme du genre chrysosporium utile pour preparer des inhibiteurs de farnesyl transferase
US08/894,038 US5849724A (en) 1995-02-17 1996-01-19 Microorganism of genus chrysosporium for use in preparing farnesyl transferase inhibitors
PCT/FR1996/000089 WO1996025512A1 (fr) 1995-02-17 1996-01-19 Microorganisme du genre chrysosporium utile pour preparer des inhibiteurs de farnesyl transferase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9501866A FR2730734B1 (fr) 1995-02-17 1995-02-17 Nouveaux composes manifestant des proprietes inhibitrices de farnesyl transferase et microorganisme du genre chrysosporium susceptible d'etre utilise pour les preparer

Publications (2)

Publication Number Publication Date
FR2730734A1 FR2730734A1 (fr) 1996-08-23
FR2730734B1 true FR2730734B1 (fr) 1997-03-28

Family

ID=9476268

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9501866A Expired - Fee Related FR2730734B1 (fr) 1995-02-17 1995-02-17 Nouveaux composes manifestant des proprietes inhibitrices de farnesyl transferase et microorganisme du genre chrysosporium susceptible d'etre utilise pour les preparer

Country Status (6)

Country Link
US (1) US5849724A (fr)
EP (1) EP0809707A1 (fr)
JP (1) JPH11500615A (fr)
CA (1) CA2211167A1 (fr)
FR (1) FR2730734B1 (fr)
WO (1) WO1996025512A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2306480A (en) * 1995-10-30 1997-05-07 Merck & Co Inc Antifungal agents
US5770587A (en) * 1995-10-30 1998-06-23 Merck & Co., Inc. Antifungal agents
EP1363594B1 (fr) * 2001-03-02 2007-11-21 MERCK PATENT GmbH Formulations cosmetiques renfermant des derives de flavonoides
US20050130256A1 (en) * 2001-09-26 2005-06-16 Northeastern University Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
US7011957B2 (en) * 2001-09-26 2006-03-14 Northeastern University Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
US20030059866A1 (en) * 2001-09-26 2003-03-27 Kim Lewis Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
CN109503696A (zh) * 2019-01-04 2019-03-22 云南中烟工业有限责任公司 一种具有抗菌功能的三萜类化合物及其制备方法与在电子烟中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641537A1 (fr) * 1989-01-09 1990-07-13 Centre Nat Rech Scient Phosphates d'oxysteryle, synthese et utilisation comme agent pharmaceutique
GB9118465D0 (en) * 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
JPH07316145A (ja) * 1994-05-25 1995-12-05 Kobe Steel Ltd 新規な６−オキサビシクロ［３．２．０ヘプタンのスピロ誘導体、抗腫瘍剤、ヒト腫瘍細胞に対する選択的細胞障害剤、該誘導体の生産菌及びその製造方法

Also Published As

Publication number Publication date
CA2211167A1 (fr) 1996-08-22
EP0809707A1 (fr) 1997-12-03
JPH11500615A (ja) 1999-01-19
US5849724A (en) 1998-12-15
WO1996025512A1 (fr) 1996-08-22
FR2730734A1 (fr) 1996-08-23

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Legal Events

Date Code Title Description
ST Notification of lapse