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FR2797273B1 - Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique - Google Patents

Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique

Info

Publication number
FR2797273B1
FR2797273B1 FR9910270A FR9910270A FR2797273B1 FR 2797273 B1 FR2797273 B1 FR 2797273B1 FR 9910270 A FR9910270 A FR 9910270A FR 9910270 A FR9910270 A FR 9910270A FR 2797273 B1 FR2797273 B1 FR 2797273B1
Authority
FR
France
Prior art keywords
heart
applications
gene
gene expression
gene therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9910270A
Other languages
English (en)
Other versions
FR2797273A1 (fr
Inventor
Margaret Buckingham
Marguerite Lemonnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur filed Critical Institut Pasteur
Priority to FR9910270A priority Critical patent/FR2797273B1/fr
Priority to CA002381325A priority patent/CA2381325A1/fr
Priority to EP00956629A priority patent/EP1204760A2/fr
Priority to PCT/FR2000/002257 priority patent/WO2001011064A2/fr
Priority to AU68508/00A priority patent/AU6850800A/en
Priority to JP2001515849A priority patent/JP2003506094A/ja
Publication of FR2797273A1 publication Critical patent/FR2797273A1/fr
Application granted granted Critical
Publication of FR2797273B1 publication Critical patent/FR2797273B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Environmental Sciences (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR9910270A 1999-08-06 1999-08-06 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique Expired - Fee Related FR2797273B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9910270A FR2797273B1 (fr) 1999-08-06 1999-08-06 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique
CA002381325A CA2381325A1 (fr) 1999-08-06 2000-08-04 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique
EP00956629A EP1204760A2 (fr) 1999-08-06 2000-08-04 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique
PCT/FR2000/002257 WO2001011064A2 (fr) 1999-08-06 2000-08-04 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique
AU68508/00A AU6850800A (en) 1999-08-06 2000-08-04 Polynucleotides regulating the activation of the expression of a gene in the heart and its uses in gene therapy
JP2001515849A JP2003506094A (ja) 1999-08-06 2000-08-04 心臓における遺伝子発現を活性化するポリヌクレオチドおよび遺伝子治療におけるその使用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9910270A FR2797273B1 (fr) 1999-08-06 1999-08-06 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique

Publications (2)

Publication Number Publication Date
FR2797273A1 FR2797273A1 (fr) 2001-02-09
FR2797273B1 true FR2797273B1 (fr) 2004-01-02

Family

ID=9548982

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9910270A Expired - Fee Related FR2797273B1 (fr) 1999-08-06 1999-08-06 Polynucleotides dirigeant l'activation de l'expression d'un gene dans le coeur et ses applications a la therapie genique

Country Status (6)

Country Link
EP (1) EP1204760A2 (fr)
JP (1) JP2003506094A (fr)
AU (1) AU6850800A (fr)
CA (1) CA2381325A1 (fr)
FR (1) FR2797273B1 (fr)
WO (1) WO2001011064A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2778945A1 (fr) 2009-10-29 2011-05-05 Vib Vzw Elements regulateurs de l'acide nucleique specifique du cƒur et procedes et utilisation de ceux-ci
WO2016123163A2 (fr) 2015-01-27 2016-08-04 Kardiatonos, Inc. Biomarqueurs de maladies vasculaires
AR126407A1 (es) * 2021-07-08 2023-10-11 Tenaya Therapeutics Inc Casetes de expresión optimizada para genoterapia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4849593A (en) * 1992-09-04 1994-03-29 Children's Medical Center Corporation Myocyte-specific transcription enhancing factor 2
US5834306A (en) * 1994-12-23 1998-11-10 Sri International Tissue specific hypoxia regulated therapeutic constructs

Also Published As

Publication number Publication date
WO2001011064A3 (fr) 2001-06-07
EP1204760A2 (fr) 2002-05-15
FR2797273A1 (fr) 2001-02-09
AU6850800A (en) 2001-03-05
WO2001011064A2 (fr) 2001-02-15
JP2003506094A (ja) 2003-02-18
CA2381325A1 (fr) 2001-02-15

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Legal Events

Date Code Title Description
ST Notification of lapse